990
Views
17
CrossRef citations to date
0
Altmetric
Research Paper

Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer

, , , &
Pages 163-168 | Received 17 Jun 2015, Accepted 12 Nov 2015, Published online: 20 Jan 2016

References

  • Warburg O, Posener K, Negelein E. Über den Stoffwechsel der Carcinomzelle. Biochem Z 1924; 152:309-44; http://dx.doi.org/10.1007/BF01504608
  • Wittig R, Coy JF. The role of glucose metabolism and glucose-associated signalling in cancer. Perspect Medicin Chem 2008; 1:64-82; PMID:19812737
  • Xu X, Hausen Zur A, Coy JF, Löchelt M. Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells. Int J Cancer 2009; 124:1330-7; PMID:19065656; http://dx.doi.org/10.1002/ijc.24078
  • Langbein S, Zerilli M, Hausen Zur A, Staiger W, Rensch-Boschert K, Lukan N, Popa J, Ternullo MP, Steidler A, Weiss C, et al. Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. Br J Cancer 2006; 94:578-85; PMID:16465194; http://dx.doi.org/10.1038/sj.bjc.6602962
  • Schultz H, Kähler D, Branscheid D, Vollmer E, Zabel P, Goldmann T. TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens. Diagn Pathol 2008; 3:35; PMID:18700018; http://dx.doi.org/10.1186/1746-1596-3-35
  • Sun W, Liu Y, Glazer CA, Shao C, Bhan S, Demokan S, Zhao M, Rudek MA, Ha PK, Califano JA. TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization. Clin Cancer Res 2010; 16:857-66; PMID:20103683; http://dx.doi.org/10.1158/1078-0432.CCR-09-2604
  • Kayser G, Sienel W, Kubitz B, Mattern D, Stickeler E, Passlick B, Werner M, Hausen Zur A. Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression. Pathology 2011; 43:719-24; PMID:22027741; http://dx.doi.org/10.1097/PAT.0b013e32834c352b
  • Krockenberger M, Engel JB, Schmidt M, Kohrenhagen N, Häusler SFM, Dombrowski Y, Kapp M, Dietl J, Honig A. Expression of transketolase-like 1 protein (TKTL1) in human endometrial cancer. Anticancer Res 2010; 30:1653-9; PMID:20592357
  • Schmidt M, Voelker H-U, Kapp M, Krockenberger M, Dietl J, Kammerer U. Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK. J Cancer Res Clin Oncol 2010; 136:219-25; PMID:19655166; http://dx.doi.org/10.1007/s00432-009-0652-y
  • Chen H, Yue J-X, Yang S-H, Ding H, Zhao R-W, Zhang S. Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer. J Exp Clin Cancer Res 2009; 28:43; PMID:19331662; http://dx.doi.org/10.1186/1756-9966-28-43
  • Schwaab J, Horisberger K, Ströbel P, Bohn B, Gencer D, Kähler G, Kienle P, Post S, Wenz F, Hofmann W-K, et al. Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy. BMC Cancer 2011; 11:363; PMID:21854597; http://dx.doi.org/10.1186/1471-2407-11-363
  • Lange CA, Tisch-Rottensteiner J, Böhringer D, Martin G, Schwartzkopff J, Auw-Haedrich C. Enhanced TKTL1 expression in malignant tumors of the ocular adnexa predicts clinical outcome. Ophthalmology 2012; 119:1924-9; PMID:22658715; http://dx.doi.org/10.1016/j.ophtha.2012.03.037
  • Grimm M, Hoefert S, Luz O, Reinert S, Polligkeit J. Transketolase-like protein 1 expression in recurrent oral squamous cell carcinoma after curative resection: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol 2013; 116:e173-8; PMID:22819458; http://dx.doi.org/10.1016/j.oooo.2011.12.022
  • Grimm M, Munz A, Teriete P, Nadtotschi T, Reinert S. GLUT-1(+)/TKTL1(+) coexpression predicts poor outcome in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol 2014; 117:743-53; PMID:24703406; http://dx.doi.org/10.1016/j.oooo.2014.02.007
  • Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2014; 136:359–386; PMID:25220842
  • Böckelman C, Engelmann BE, Kaprio T, Hansen TF, Glimelius B. Risk of recurrence in patients with colon cancer stage II and III: A systematic review and meta-analysis of recent literature. Acta Oncol 2015; 54:5-16; PMID:25430983; http://dx.doi.org/10.3109/0284186X.2014.975839
  • Hu L-H, Yang J-H, Zhang D-T, Zhang S, Wang L, Cai P-C, Zheng J-F, Huang J-S. The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells. Anticancer Drugs 2007; 18:427-33; PMID:17351395; http://dx.doi.org/10.1097/CAD.0b013e328013d99e
  • Bentz S, Cee A, Endlicher E, Wojtal KA, Naami A, Pesch T, Lang S, Schubert P, Fried M, Weber A, et al. Hypoxia induces the expression of transketolase-like 1 in human colorectal cancer. Digestion 2013; 88:182-92; PMID:24193262; http://dx.doi.org/10.1159/000355015
  • Coy JF, Dressler D, Wilde J, Schubert P. Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer. Clin Lab 2005; 51:257-73; PMID:15991799
  • Diaz-Moralli S, Tarrado-Castellarnau M, Alenda C, Castells A, Cascante M. Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation. PLoS ONE 2011; 6:e25323; PMID:21980427; http://dx.doi.org/10.1371/journal.pone.0025323
  • Rieger J, Bähr O, Maurer GD, Hattingen E, Franz K, Brucker D, Walenta S, Kammerer U, Coy JF, Weller M, et al. ERGO: a pilot study of ketogenic diet in recurrent glioblastoma. Int J Oncol 2014; 44:1843-52; PMID:24728273; http://dx.doi.org/10.3892/ijo.2014.2382
  • Kononen J, Bubendorf L, Kallioniemi A, Bärlund M, Schraml P, Leighton S, Torhorst J, Mihatsch MJ, Sauter G, Kallioniemi OP. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 1998; 4:844-7; PMID:9662379; http://dx.doi.org/10.1038/nm0798-844
  • Nocito A, Kononen J, Kallioniemi OP, Sauter G. Tissue microarrays (TMAs) for high-throughput molecular pathology research. Int J Cancer 2001; 94:1-5; PMID:11668471; http://dx.doi.org/10.1002/ijc.1385
  • Kallioniemi OP, Wagner U, Kononen J, Sauter G. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet 2001; 10:657-62; PMID:11257096; http://dx.doi.org/10.1093/hmg/10.7.657
  • Torhorst J, Bucher C, Kononen J, Haas P, Zuber M, Köchli OR, Mross F, Dieterich H, Moch H, Mihatsch M, et al. Tissue microarrays for rapid linking of molecular changes to clinical endpoints. Am J Pathol 2001; 159:2249-56; PMID:11733374; http://dx.doi.org/10.1016/S0002-9440(10)63075-1
  • Böckelman C, Koskensalo S, Hagström J, Lundin M, Ristimäki A, Haglund C. CIP2A overexpression is associated with c-Myc expression in colorectal cancer. Cancer Biol Ther 2012; 13:289-95; PMID:22310977; http://dx.doi.org/10.4161/cbt.18922

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.