Cancer Biology & Therapy, Volume 17, Issue 2 (2016)

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Cancer Biology & Therapy, Volume 17, Issue 2 (2016)

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Journal Club

Article
The promising role of nivolumab in renal cell cancers
Kanika Gupta, Dorenett Yu Tiu, John Tiu & Jeanny B. Aragon-Ching
Pages: 123-124
Published online: 26 Feb 2016
AbstractforThe promising role of nivolumab in renal cell cancers | Full Text | References | PDF (186.4 KB)
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Bedside to Bench Report

How breast cancer chemotherapy increases the risk of leukemia: Thoughts about a case of diffuse large B-cell lymphoma and leukemia after breast cancer chemotherapy
Bin Zhang, Xia Zhang, Minghuan Li, Li Kong, Xiaoqin Deng & Jinming Yu
Pages: 125-128
Published online: 25 Feb 2016
AbstractforHow breast cancer chemotherapy increases the risk of leukemia: Thoughts about a case of diffuse large B-cell lymphoma and leukemia after breast cancer chemotherapy | Full Text | References | PDF (443.6 KB)
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Research Paper

Article
Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor
Christine M. Kivlin, Kelsey L. Watson, Ghadah A. Al Sannaa, Roman Belousov, Davis R. Ingram, Kai-Lieh Huang, Caitlin D. May, Svetlana Bolshakov, Sharon M. Landers, Azad Abul Kalam, John M. Slopis, Ian E. McCutcheon, Raphael E. Pollock, Dina Lev, Alexander J. Lazar & Keila E. Torres
Pages: 129-138
Published online: 26 Jan 2016
AbstractforPoly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
A human IgG-like bispecific antibody co-targeting epidermal growth factor receptor and the vascular endothelial growth factor receptor 2 for enhanced antitumor activity
Zhiguo Chen, Wei Xie, Desmond Omane Acheampong, Menghuai Xu, Hua He, Mengqi Yang, Chenchen Li, Chen Luo, Min Wang & Juan Zhang
Pages: 139-150
Published online: 29 Jan 2016
AbstractforA human IgG-like bispecific antibody co-targeting epidermal growth factor receptor and the vascular endothelial growth factor receptor 2 for enhanced antitumor activity | Full Text | References | PDF (1.7 MB)
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Article
Upregulation of PP2Ac predicts poor prognosis and contributes to aggressiveness in hepatocellular carcinoma
Shao-Juan Gong, Xiao-Jun Feng, Wei-Hua Song, Jian-Ming Chen, Shou-Mei Wang, Dong-Juan Xing, Ming-Hua Zhu, Shu-Hui Zhang & Ai-Min Xu
Pages: 151-162
Published online: 22 Jan 2016
AbstractforUpregulation of PP2Ac predicts poor prognosis and contributes to aggressiveness in hepatocellular carcinoma | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer
Kaisa Ahopelto, Camilla Böckelman, Jaana Hagström, Selja Koskensalo & Caj Haglund
Pages: 163-168
Published online: 20 Jan 2016
AbstractforTransketolase-like protein 1 expression predicts poor prognosis in colorectal cancer | Full Text | References | PDF (503 KB)
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Article
Effects of methylglyoxal and glyoxalase I inhibition on breast cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2
Yi Guo, Yuning Zhang, Xunjun Yang, Panpan Lu, Xijuan Yan, Fanglan Xiao, Huaibin Zhou, Chaowei Wen, Mengru Shi, Jianxin Lu & Qing H. Meng
Pages: 169-180
Published online: 12 Feb 2016
AbstractforEffects of methylglyoxal and glyoxalase I inhibition on breast cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2 | Full Text | References | PDF (1.5 MB)
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Article
E6 viral protein ratio correlates with outcomes in human papillomavirus related oropharyngeal cancer
Angela Hong, Xiaoying Zhang, Deanna Jones, Mei Zhang, C. Soon Lee, J. Guy Lyons, Anne-Sophie Veillard & Barbara Rose
Pages: 181-187
Published online: 22 Feb 2016
AbstractforE6 viral protein ratio correlates with outcomes in human papillomavirus related oropharyngeal cancer | Full Text | References | PDF (379.7 KB)
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Article
Hypoxia regulates ABCG2 activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells
Xiaodan He, Juan Wang, Wei Wei, Meiyan Shi, Beibei Xin, Ti Zhang & Xiaohong Shen
Pages: 188-198
Published online: 22 Feb 2016
AbstractforHypoxia regulates ABCG2 activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells | Full Text | References | PDF (1.4 MB)
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Article
EBI-907, a novel BRAFV600E inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile
Jiayin Zhang, Biao Lu, Dong Liu, Ru Shen, Yinfa Yan, Liuqing Yang, Minsheng Zhang, Lei Zhang, Guoqing Cao, Hu Cao, Beibei Fu, Aishen Gong, Qiming Sun, Hong Wan, Lianshan Zhang, Weikang Tao & Jingsong Cao
Pages: 199-207
Published online: 22 Feb 2016
AbstractforEBI-907, a novel BRAFV600E inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile | Full Text | References | PDF (999.6 KB)
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Article
Radiotherapy diagnostic biomarkers in radioresistant human H460 lung cancer stem-like cells
Hong Shik Yun, Jeong-Hwa Baek, Ji-Hye Yim, Hong-Duck Um, Jong Kuk Park, Jie-Young Song, In-Chul Park, Jae-Sung Kim, Su-Jae Lee, Chang-Woo Lee & Sang-Gu Hwang
Pages: 208-218
Published online: 22 Feb 2016
AbstractforRadiotherapy diagnostic biomarkers in radioresistant human H460 lung cancer stem-like cells | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Dysregulation of splicing proteins in head and neck squamous cell carcinoma
Aneesha Radhakrishnan, Vishalakshi Nanjappa, Remya Raja, Gajanan Sathe, Sandip Chavan, Raja Sekhar Nirujogi, Arun H. Patil, Hitendra Solanki, Santosh Renuse, Nandini A. Sahasrabuddhe, Premendu P. Mathur, T. S. Keshava Prasad, Prashant Kumar, Joseph A. Califano, David Sidransky, Akhilesh Pandey, Harsha Gowda & Aditi Chatterjee
Pages: 219-229
Published online: 22 Feb 2016
AbstractforDysregulation of splicing proteins in head and neck squamous cell carcinoma | Full Text | References | PDF (1.5 MB) | Supplemental
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