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Commentary

IRGM restrains NLRP3 inflammasome activation by mediating its SQSTM1/p62-dependent selective autophagy

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Pages 1645-1647 | Received 21 Apr 2019, Accepted 03 Jun 2019, Published online: 20 Jun 2019

Reference

  • Mehto S, Jena KK, Nath P, et al. The Crohn’s disease risk factor IRGM limits NLRP3 inflammasome activation by impeding its assembly and by mediating its selective autophagy. Mol Cell. 2019 Feb 7;73(3):429–445.e7.

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