1,365
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion

, , , , &

References

  • Audia S, Mahévas M, Samson M, et al. Pathogenesis of immune thrombocytopenia. Autoimmun Rev. 2017;16(6):620–632.
  • Kuwana M, Okazaki Y, Kaburaki J, et al. Spleen is a primary site for activation of platelet-reactive T and B cells in patients with immune thrombocytopenic purpura. J Immunol. 2002;168(7):3675–3682.
  • Segal JB, Powe NR. Prevalence of immune thrombocytopenia: analyses of administrative data. J Thromb Haemost. 2006;4(11):2377–2383.
  • Deane S, Teuber SS, Gershwin ME. The geoepidemiology of immune thrombocytopenic purpura. Autoimmun Rev. 2010;9(5):A342–A349.
  • Kühne T. Idiopathic thrombocytopenic purpura in childhood: controversies and solutions. Pediatr Blood Cancer. 2006;47(5 Suppl):650–652.
  • Psaila B, Bussel JB. Immune thrombocytopenic purpura. Hematol Oncol Clin North Am. 2007;21(4):743–759., vii.
  • Geng Y, Sun XL, Su AY, et al. Expression of CD19(+)B cells and involvement of serum breg in pathogenesis of immune thrombocytopenia. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019;27(3):911–915.
  • Alavi S, Aryan Z, Ghazizadeh F, et al. The immunophenotype of bone marrow lymphocytes in children with immune thrombocytopenic purpura. Pediatr Hematol Oncol. 2014;31(6):548–554.
  • Mahévas M, Patin P, Huetz F, et al. B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells. J Clin Invest. 2013;123(1):432–442.
  • Levy-Mendelovich S, Lev A, Aviner S, et al. Quantification of specific T and B cells immunological markers in children with chronic and transient ITP. Pediatr Blood Cancer. 2017;64(12):e26646.
  • Guo L, Kapur R, Aslam R, et al. CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell-mediated immune thrombocytopenia. Blood. 2016;127(6):735–738.
  • Audia S, Rossato M, Trad M, et al. B cell depleting therapy regulates splenic and circulating T follicular helper cells in immune thrombocytopenia. J Autoimmun. 2017;77:89–95.
  • Tsubata T. CD72 is a negative regulator of B cell responses to nuclear lupus self-antigens and development of systemic lupus erythematosus. Immune Netw. 2019;19(1):e1.
  • Venkataraman C, Lu P-J, Buhl AM, et al. CD72-mediated b cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3-kinase. Eur J Immunol. 1998;28(10):3003–3016.
  • Wu Y, Nadler MJS, Brennan LA, et al. The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1. Curr Biol. 1998;8(18):1009–1017.
  • Kumanogoh A, Shikina T, Watanabe C, et al. Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment. Int Immunol. 2005;17(10):1277–1282.
  • Kuklina Е, Nekrasova IV, Valieva YV. Involvement of semaphorin (Sema4D) in T-dependent activation of B cells. Bull Exp Biol Med. 2017;163(4):447–450.
  • Li BJ, He Y, Zhang Y, et al. Interferon-α-induced CD100 on naïve CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction. J Int Med Res. 2017;45(1):89–100.
  • Xu J, Lu S, Tao J, et al. CD72 polymorphism associated with child-onset of idiopathic thrombocytopenic purpura in Chinese patients. J Clin Immunol. 2008;28(3):214–219.
  • Lyu M, Hao Y, Li Y, et al. Upregulation of CD72 expression on CD19(+) CD27(+) memory B cells by CD40L in primary immune thrombocytopenia. Br J Haematol. 2017;178(2):308–318.
  • Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood. 2009;113(11):2386–2393.
  • Jiang X, Björkström NK, Melum E. Intact CD100-CD72 interaction necessary for TCR-induced T cell proliferation. Front Immunol. 2017;8:765.
  • Wu HJ, Bondada S. CD72, a coreceptor with both positive and negative effects on B lymphocyte development and function. J Clin Immunol. 2009;29(1):12–21.
  • Shen Y, Ma Y, Xie J, et al. A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren's syndrome. BMC Immunol. 2020;21(1):21.
  • Asmiyou A, Bakr Ashraf M, Shahin DA, et al. CD40 and CD72 expression and prognostic values among children with systemic lupus erythematosus: a case-control study. Lupus. 2020;29(10):1270–1276.
  • Vadasz Z, Goldeberg Y, Halasz K, et al. Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis. Clin Immunol. 2016;164:114–118.
  • Zhou H, Qi A-P, Li H-Y, et al. CD72 gene expression in immune thrombocytopenia. Platelets. 2012;23(8):638–644.
  • Pan C, Baumgarth N, Parnes JR. CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation. Immunity. 1999;11(4):495–506.
  • Ogimoto M. Impairment of B cell receptor-mediated Ca2 + influx, activation of mitogen-activated protein kinases and growth inhibition in CD72-deficient BAL-17 cells. Int Immunol. 2004;16(7):971–982.
  • Li DH, Tung JW, Tarner IH, et al. CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. J Immunol. 2006;176(9):5321–5328.
  • Wu HJ, Venkataraman C, Estus S, et al. Positive signaling through CD72 induces mitogen-activated protein kinase activation and synergizes with B cell receptor signals to induce X-linked immunodeficiency B cell proliferation. J Immunol. 2001;167(3):1263–1273.
  • Wakabayashi C, Adachi T, Wienands J, et al. A distinct signaling pathway used by the IgG-containing B cell antigen receptor. Science. 2002;298(5602):2392–2395.
  • Nakano S, Morimoto S, Suzuki J, et al. Down-regulation of CD72 and increased surface IgG on B cells in patients with lupus nephritis. Autoimmunity. 2007;40(1):9–15.
  • Yu H, Liu Y, Han J, et al. TLR7 regulates dendritic cell-dependent B-cell responses through BlyS in immune thrombocytopenic purpura. Eur J Haematol. 2011;86(1):67–74.
  • Hou M, Lv B, He Q, et al. Both splenic CD5(+) B and CD5(-) B cells produce platelet glycoprotein-specific autoantibodies in chronic ITP. Thromb Res. 2003;110(1):1–5.
  • Takahashi A, Iwabuchi K, Suzuki M, et al. Antisense macrophage migration inhibitory factor (MIF) prevents anti-IgM mediated growth arrest and apoptosis of a murine B cell line by regulating cell cycle progression. Microbiol Immunol. 1999;43(1):61–67.
  • Li H, Niederkorn JY, Neelam S, et al. Immunosuppressive factors secreted by human amniotic epithelial cells. Invest Ophthalmol Vis Sci. 2005;46(3):900–907.
  • Schmitz C, Noels H, Bounkari OE, et al. Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. Faseb J. 2018;32(8):4428–4443.
  • Rijvers L, Melief M-J, van der Vuurst de Vries RM, et al. The macrophage migration inhibitory factor pathway in human B cells is tightly controlled and dysregulated in multiple sclerosis. Eur J Immunol. 2018;48(11):1861–1871.
  • Wang Y, Wang S, Gong C, et al. iTRAQ-based quantitative proteomics analysis of immune thrombocytopenia patients before and after Qishunbaolier treatment. Rapid Commun Mass Spectrom. 2021;35(3):e8993.
  • Kennedy DE, Knight KL. Inhibition of B lymphopoiesis by adipocytes and IL-1-producing myeloid-derived suppressor cells. J Immunol. 2015;195(6):2666–2674.