In vitro cytotoxicity screening of some 3-substituted-4-oxo-imidazolidin-2-(1H)-thione derivatives as anticancer drug

References

• Senwar K, Reddy T, Thummuri D, et al. Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3′-methoxy-4′-(2-amino-2-oxoethoxy)-benzylidene) indolin-2-ones as potential antitumor agents. Eur J Med Chem. 2016;118:34–46. doi:10.1016/j.ejmech.2016.04.025
   PubMed Web of Science ®Google Scholar
• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality world-wide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424. doi:10.3322/caac.21492
   PubMed Web of Science ®Google Scholar
• Subramanian S, Boggu P, Yun J, et al. Identification of N-aryl sulfonyl-pyrimid ones as anticancer agents. Arch Pharmacal Res A Publ PSK. 2018;41:251–258. doi:10.1007/s12272-018-1003-9
   PubMed Web of Science ®Google Scholar
• Sung H, Ferlay J, Siegel R, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209–249. doi:10.3322/caac.21660
   PubMed Web of Science ®Google Scholar
• Taiwan News. [ accessed on 2020 August 12]. www.taiwannews.com.tw/en/news/3948748
   Google Scholar
• Mourad A, Rizzk Y, Zaki I, et al. Design, synthesis, cytotoxic screening and molecular docking studies of novel hybrid thio-semicarbazone derivatives as anticancer agents. J Mol Struct. 2021;1242:13072. doi:10.1016/j.molstruc.2021.130722
   Google Scholar
• Ahmad A, Varshney H, Rauf A, et al. Synthesis and anticancer activity of long chain substituted 1,3,4-oxadiazol-2-thione, 1,2,4-triazol-3-thione and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives. Arab J Chem. 2017;46(S2):S3347–S3357. doi:10.1016/j.arabjc.2014.01.015
   Google Scholar
• Anant A, Ali A, Ali A, et al. A Computational approach to discover potential quinazoline derivatives against CDK4/6 kinase. J Mol Struct. 2021;1245:131079. doi:10.1016/j.molstruc.2021.131079
   Web of Science ®Google Scholar
• Vitaku E, Smith D, Njardarson J. Analysis of the structural diversity, substitution patterns, and frequency of nitrogen hetero-cycles among US. FDA Approv Pharm J Med Chem. 2014;57:10257–10274. doi:10.1021/jm501100b
   PubMed Web of Science ®Google Scholar
• Salman A, Abdel-Aziem A, Alkubbat M. Design, synthesis of some new thio-substituted imidazole and their biological activity. Am J Org Chem. 2015;5:57–72. doi:10.5923/j.ajoc.20150502.01
   Google Scholar
• Nagalakshmi G. Synthesis and pharmacological evaluation of 2-(4-halosubstituted phenyl)-4,5-diphenyl-1H-imidazoles. J Chem. 2008;5:447–452. doi:10.1155/2008/921256
   Web of Science ®Google Scholar
• Gangadhar S, Ramesh D, Mahajan S. Synthesis, characterization and anticonvulsant activity of 3-substituted 2-thiohydantoin derivatives. Semant Sch IJRPC. 2013;3:793–796.
   Google Scholar
• Ali I, Lone M, Aboul-Enein H. Imidazoles as potential anticancer agents. RSC Med Chem Commun. 2017;8:1731–1864. doi:10.1039/c7md00067g
   Google Scholar
• Yoshino H, Sato H, Shiraishi T, et al. Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of a castration-resistant prostate cancer. Natl Libr Med. 2010;18:8150–8157. doi:10.1016/j.bmc.2010.10.023
   Google Scholar
• Shih C, Wu J, Liu Y, et al. Anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH) in human vascular endothelial cells. Biochem Pharm. 2004;67:67–75. doi:10.1016/j.bcp.2003.08.018
   PubMed Web of Science ®Google Scholar
• El-Sharief A, Moussa Z. Synthesis, characterization and derivatization of some novel types of mono- and bis-imidazolidine-iminothiones and imidazolidine-iminodithiones with antitumor, antiviral, antibacterial and antifungal activities. Eur J Med Chem. 2009;44:4315–4334. doi:10.1016/j.ejmech.2009.07.019
   PubMed Web of Science ®Google Scholar
• Abadi A, Gary B, Tinsley H, et al. Synthesis, molecular modeling and biological evaluation of novel tadalafil analogs as phosphodiesterase and colon tumor cell growth inhibitors, new stereochemical perspective. Eur J Med Chem. 2010;45:1278–1286. doi:10.1016/j.ejmech.2009.10.046
   PubMed Web of Science ®Google Scholar
• Moussa Z, El-Sharief A, El-Sharief S. Synthesis and characterization of new types of halogenated and alkylated imidazoli-dine-iminothiones and a comparative study of their antitumor, antibacterial, and antifungal activities. Natl Libr Med. 2011;46:2280–2289. doi:10.1016/j.ejmech.2011.03.009
   Google Scholar
• Aziz M, Khoobi M, Ramazani A, et al. A. 2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents. Natl Libr Med. 2013;59:15–22. doi:10.1016/j.ejmech.2012.10.044
   Google Scholar
• El Hady H, El-Sayed R, Al-nathali H. Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties. Chem Cent J. 2018;51:3–12. doi:10.1186/s13065-018-0418-1
   Google Scholar
• Hong-Ping Z, Ke X, Xiang-Hong H, et al. Organocatalytic diastereoselective [3+2] cyclization of MBH carbonates with dinucleophiles: synthesis of bicyclic imidazoline derivatives that inhibit MDM2-p53 interaction. Chem Comm. 2019;3:11374–11377. doi:10.1039/C9CC05916D
   Google Scholar
• Vasir J, Labhasetwar V. Targeted drug delivery in cancer therapy. Technol Cancer Res Treat. 2005;4:363–374. doi:10.1177/153303460500400405
   PubMed Web of Science ®Google Scholar
• Han J, Talorete T, Yamada P, et al. Antiproliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology. 2009;59:45–53. doi:10.1007/s10616-009-9191-2
   PubMed Web of Science ®Google Scholar
• Wu C, Chen Y, Chen J, et al. Terpinen-4-ol induces apoptosis in human non-small cell lung cancer in vitro and in vivo. Evid-Based Complement Altern Med. 2012;2012:818261. doi:10.1155/2012/818261
   PubMed Web of Science ®Google Scholar
• Zaki I, Abdelhameid M, El-Deen I, et al. Design, synthesis and screening of 1,2,4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell lines. Eur J Med Chem. 2018;156:563–579. doi:10.1016/j.ejmech.2018.07.003
   PubMed Web of Science ®Google Scholar
• Khazaei S, Esa N, Ramachandran V, et al. In vitro antiproliferative and apoptosis inducing effect of allium atroviolaceum bulb extract on breast, cervical, and liver cancer cells. Front Pharmacol. 2017;8:1–16. doi:10.3389/fphar.2017.00005
   PubMed Web of Science ®Google Scholar
• Marcotte D, Zeng W, Hus J, et al. Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism. Bioorg Med Chem. 2013;21:4011–4019. doi:10.1016/j.bmc.2013.04.019
   PubMed Web of Science ®Google Scholar
• Thomsen R, Christensen M. A new technique for high accuracy molecular docking. J Med Chem. 2006;49:3315–3321. doi:10.1021/jm051197e
   PubMed Web of Science ®Google Scholar
• Fayed E, Sabour M, Harras A, et al. Design, synthesis, biological evaluation and molecular modeling of new coumarin derivatives as potent anticancer agents. Med Chem Res. 2019;28:1284–1297. doi:10.1007/s00044-019-02373-x.D
   Web of Science ®Google Scholar
• Kheirollahi A, Pordeli M, Safavi M, et al. Cytotoxic and apoptotic effects of synthetic benzochromene derivatives on human cancer cell lines. Naunyn-Schmiedeberg's Arch Pharmacol. 2014;387:1199–1208. doi:10.1007/s00210-014-1038-5
   Google Scholar
• Zhu J, Wang H, Chen F, et al. An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy. Free Radic. Biol. Med. 2016;99:544–556. doi:10.1016/j.freeradbiomed.2016.09.010
   PubMed Web of Science ®Google Scholar