References

• Altaki , M.S. , Santos , F.J. and Galceran , M.T. 2007 . Analysis of furan in foods by headspace solid-phase microextraction-gas chromatography-ion trap mass spectrometry . Journal of Chromatography A , 1146 : 103 – 109 .
   PubMed Web of Science ®Google Scholar
• Becalski , A. and Seaman , S. 2005 . Furan precursors in food: A model study and development of a simple headspace method for determination of furan . Journal of AOAC International , 88 : 102 – 106 .
   PubMed Web of Science ®Google Scholar
• Bianchi , F. , Careri , M. , Mangia , A. and Musci , M. 2006 . Development and validation of a solid phase micro-extraction-gas-chromatography-mass-spectrometry method for the determination of furan in baby-food . Journal of Chromatography A , 110 : 268 – 272 .
   Google Scholar
• Byrns , M.C. , Vu , C. , Neidigh , J.W. , Abad , J.L. , Jones , R.A. and Peterson , L.A. 2006 . Detection of DNA adducts derived from the reactive metabolite of furan, cis-2-butene-1,4-dial . Chemical Research in Toxicology , 19 : 414 – 420 .
   PubMed Web of Science ®Google Scholar
• Carrascosa Lezcano , A. , Fernández García , J.M. , Fernández Ramos , C. , Ferrández Longás , A. , López-Siguero , J.P. , Sánchez González , E. and Yeste Fernández , D. 2008 . Estudio transversal español de crecimiento 2008. Parte II: valores de talla, peso e índice de masa corporal desde el nacimiento a la talla adulta . Anales de Pediatría , 68 : 552 – 569 .
   PubMedGoogle Scholar
• Delgado-Andrade , C. , Rufián-Henares , J.A. and Morales , F.J. 2009 . Hydroxymethylfurfural in commercial biscuits marketed in Spain . Journal of Food and Nutrition Research , 48 : 14 – 19 .
   Web of Science ®Google Scholar
• EFSA (European Food Safety Authority) . 2004 . Report of the scientific panel on contaminants in the Food Chain on provisional findings on furan in food . EFSA Journal , 2 : 137
   Google Scholar
• EFSA (European Food Safety Authority) . 2009 . Scientific document: Results on the monitoring of furan levels in food . EFSA Journal , 7 : 304
   Google Scholar
• EFSA (European Food Safety Authority) . 2010 . Scientific Document: Update of results on the monitoring of furan levels in food . EFSA Journal , 8 : 1702
   Google Scholar
• Fan , X. , Huang , L. and Sokorai , K.J.B. 2008 . Factors affecting thermally induced furan formation . Journal of Agricultural and Food Chemistry , 56 : 9490 – 9494 .
   PubMed Web of Science ®Google Scholar
• FAO/WHO (Food and Agricultural Organization of the United Nations/World Health Organization) . 2010 . Summary and conclusions report of the seventy-second meeting of the Joint FAO/WHO Expert Committee on Food Additives , Rome : Joint FAO/WHO Expert Committee on Food Additives .
   Google Scholar
• Glatt , H. , Schneider , H. and Liu , Y. 2005 . V79-hCYP2E1-hSULT1A1, a cell line for the sensitive detection of genotoxic effects induced by carbohydrate pyrolysis products and other food-borne chemicals . Mutation Research , 580 : 41 – 52 .
   PubMed Web of Science ®Google Scholar
• Guerra-Hernández , E. , García-Villanova , B. and Montilla-Gómez , J. 1992 . Determination of hydroxymethylfurfural in baby cereals by high performance liquid chromatography . Journal of Liquid Chromatography , 15 : 2551 – 2559 .
   Web of Science ®Google Scholar
• IARC (Internacional Agency for Research on Cancer) . 1995 . Dry cleaning, some chlorinated solvents and other industrial chemicals, Monographs on the evaluation of carcinogenic risk to humans , 3194 – 3407 . Lyon , , France : World Health Organization .
   Google Scholar
• Jestoi , M. , Järvinen , T. , Järvenpää , E. and Tapanainen , H. 2009 . Furan in the baby-food samples purchased from the Finnish markets-Determination with SPME-GC-MS . Food Chemistry , 117 : 522 – 528 .
   Web of Science ®Google Scholar
• Kersting , M. , Alexy , U. , Sichhert-Hellert , W. , Manz , F. and Schöch , G. 1998 . Measured consumption of commercial infant food products in German infants: results from the Donald study . Journal of Pediatric Gastroenterology and Nutrition , 27 : 547 – 551 .
   PubMed Web of Science ®Google Scholar
• Kuballa , T. , Stier , S. and Strichow , N. 2005 . Furan in kaffee und kaffeegetränken . Deutsche Lebensmittel-Rundschau , 101 : 229 – 235 .
   Web of Science ®Google Scholar
• Lachenmeier , D.W. , Reusch , H. and Kuballa , T. 2009 . Risk assessment of furan in commercially jarred baby foods, including insights into its occurrence and formation in freshly home-cooked foods for infants and young children . Food Additives and Contaminants , 26 : 776 – 785 .
   Web of Science ®Google Scholar
• Limacher , A. , Kerler , J. , Conde-petit , B. and Blank , I. 2007 . Formation of furan and methylfuran from ascorbic acid in model systems and food . Food Additives and Contaminants , 24 : S122 – S135 .
   PubMed Web of Science ®Google Scholar
• Mercasa. Feeding in Spain 2010 (Alimentación en España 2010) . 2010 . Informe sobre Producción, Industria, Distribución y Consumo de alimentación en España Mercasa , , Spain
   Google Scholar
• Mesías-García , M. , Guerra-Hernández , E. and García-Villanova , B. 2010 . Determination of furan precursors and some thermal damage markers in baby foods: ascorbic acid, dehydroascorbic acid, hydroxymethylfurfural and furfural . Journal of Agricultural and Food Chemistry , 58 : 6027 – 6032 .
   PubMed Web of Science ®Google Scholar
• Morehouse , K.M. , Nyman , P.J. , McNeal , T.P. , Dinovi , M.J. and Perfetti , G.A. 2008 . Survey of furan in heat processed foods by headspace gas chromatography/mass spectrometry and estimated adult exposure . Food Additives and Contaminants , 25 : 259 – 264 .
   Web of Science ®Google Scholar
• NRC (National Research Council) . 2000 . Spacecraft maximum allowable concentrations for selected airborne contaminants , 307 – 329 . Washington , DC : National Academy Press .
   Google Scholar
• Nyman , P.J. , Morehouse , K.M. , McNeal , T.P. , Perfetti , G.A. and Diachenko , G.W. 2006 . Single-laboratory validation of a method for the determination of furan in food by using static headspace sampling and gas chromatography/mass spectrometry . Journal of AOAC International , 89 : 1417 – 1424 .
   PubMed Web of Science ®Google Scholar
• Owczarek-Fendor , A. , De Meulenaer , B. , Scholl , G. , Adams , A. , Van Lancker , F. , Yogendrarajah , P. and De Kimpe , N. 2010 . Furan formation from vitamin C in a starch-based model system: Influence of the reaction conditions . Food Chemistry , 121 : 1163 – 1170 .
   Web of Science ®Google Scholar
• Ruiz , E. , Santillana , M.I. , Nieto , M.T. , Cirugeda , M.E. and Sanchez , J.J. 2010 . Determination of furan in jarred baby food purchased from the Spanish market by headspace gas chromatography-mass spectrometry (HS-GC-MS) . Food Additives and Contaminants , 27 : 1208 – 1214 .
   Web of Science ®Google Scholar
• US Department of Health and Human Services . 2011 . Report on carcinogens , (12th ed. , 499 NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program . Research Triangle Park
   Google Scholar
• US Food and Drug Administration . 2004 . Determination of furan in foods , Department of Health and Human Services . Rockville, MD: FDA, US Food and Drug Administration
   Google Scholar
• Van Lancker , F. , Adams , A. , Owczarek , A. , De Meulenaer , B. and De Kimpe , N. 2009 . Impact of various food ingredients on the retention of furan in foods . Molecular Nutrition and Food Research , 53 : 1505 – 1511 .
   PubMed Web of Science ®Google Scholar
• Vranová , J. , Bednáriková , A. and Ciesarová , Z. 2007 . In-house validation of a simple headspace gas chromatography-mass spectrometry method for determination of furan levels in food . Journal of Food and Nutrition Research , 46 : 123 – 127 .
   Web of Science ®Google Scholar
• Wegener , J.W. and López-Sánchez , P. 2010 . Furan levels in fruit and vegetables juices, nutrition drinks and bakery products . Analytica Chimica Acta , 672 : 55 – 60 .
   PubMed Web of Science ®Google Scholar
• Yaylayan , V.A. 2006 . Precursors, formation and determination of furan in food . Journal für Verbraucherschutz und Lebensmittelsicherheit , 1 : 5 – 9 .
   Google Scholar
• Zoller , O. , Sager , F. and Reinhard , H. 2007 . Furan in food: Headspace method and product survey . Food Additives and Contaminants , 24 : 91 – 107 .
   PubMed Web of Science ®Google Scholar