References

• Abbe, M.J., Amin, I., Chong, P.P., Muhajir, H., & Hasbullah, S.K. (2008). Effects of cocoa extract on glucometabolism, oxidative stress, and antioxidant enzymes in obese-diabetic (ob-db) rats. Journal of Agricultural and Food Chemistry, 56(17), 7877–7884. doi:10.1021/jf8015915
   PubMed Web of Science ®Google Scholar
• Abecia-Soria, L., Pezoa-García, N.H., & Amaya-Farfan, J. (2005). Soluble albumin and biological value of protein in cocoa (Theobroma cacao L.) beans as a function of roasting time. Journal of Food Science, 70(4), S294–S298. doi:10.1111/j.1365-2621.2005.tb07205.x
   Web of Science ®Google Scholar
• Adler-Nissen, J. (1979). Determination of the degree of hydrolysis of food protein hydrolysates by trinitrobenzenesulfonic acid. Journal of Agricultural and Food Chemistry, 27(6), 1256–1262. doi:10.1021/jf60226a042
   PubMed Web of Science ®Google Scholar
• Amin, I, Jinap, S, & Jamilah, B. (1997). Vicilin-class globulins and their degradation during cocoa fermentation. Food Chemistry, 59(1), 1–5. doi:10.1016/0308-8146(95)00188-3
   Web of Science ®Google Scholar
• Amin, I., Jinap, S., Jamilah, B., Harikrisna, K., & Biehl, B. (2002). Analysis of vicilin (7S)-class globulin in cocoa cotyledons from various genetic origins. Journal of the Science of Food and Agriculture, 82(7), 728–732. doi:10.1002/jsfa.1104
   Web of Science ®Google Scholar
• Bamdad, F., Wu, J., & Chen, L. (2011). Effects of enzymatic hydrolysis on molecular structure and antioxidant activity of barley hordein. Journal of Cereal Science, 54(1), 20–28. doi:10.1016/j.jcs.2011.01.006
   Web of Science ®Google Scholar
• Bertazzo, A., Comai, S., Brunato, I., Zancato, M., & Costa, C.V.L. (2011). The content of protein and non-protein (free and protein-bound) tryptophan in Theobroma cacao beans. Food Chemistry, 124, 93–96. doi:10.1016/j.foodchem.2010.05.110
   Web of Science ®Google Scholar
• Biehl, B., Brunner, E., Passern, D., Quesnel, V.C., & Adomako, D. (1985). Acidification, proteolysis and flavor potential in fermenting cocoa beans. Journal of the Science of Food and Agriculture, 36(7), 583–598. doi:10.1002/jsfa.2740360710
   Web of Science ®Google Scholar
• Cai, L., Wu, X., Lv, Y., Xu, Y., Mi, G., & Li, J. (2015). The neuroprotective and antioxidant activities of protein hydrolysates from grass carp (Cthenopharyngodon idella) skin. Journal of Food Science and Technology, 52(6), 3750–3755. doi:10.1007/S13197-014-1438-z
   PubMed Web of Science ®Google Scholar
• Chen, N., Yang, H., Sun, Y., Niu, J., & Liu, S. (2012). Purification and identification of antioxidant peptides from walnut (Juglans regia L.) protein hydrolysates. Peptides, 38(2), 344–349. doi:10.1016/j.peptides.2012.09.017
   PubMed Web of Science ®Google Scholar
• Dávalos, A., Gómez-Cordovés, C., & Bartolome, B. (2004). Extending applicability of the oxygen radical absorbance capacity (ORAC-fluorescein) assay. Journal of Agricultural and Food Chemistry, 52(1), 48–54. doi:10.1021/jf0305231
   PubMed Web of Science ®Google Scholar
• Del Mar Contreras, M., Hernández-Ledesma, B., Amigo, L., Martín-Álvarez, P.J., & Recio, I. (2011). Production of antioxidant hydrolyzates from a whey protein concentrate with thermolysin: Optimization by response surface methodology. LWT-Food Science and Technology, 44(1), 9–15. doi:10.1016/j.lwt.2010.06.017
   Web of Science ®Google Scholar
• Di Pierro, G., O´Keeffe, M.B., Poyarkov, A., Lomolino, G., & FitzGerald, R. (2014). Antioxidant activity of bovine casein hydrolysates produced by Ficus carica L.-derived proteinase. Food Chemistry, 156, 305–311. doi:10.1016/j.foodchem.2014.01.080
   PubMed Web of Science ®Google Scholar
• Jiménez-Ruiz, E.I., Calderón De La Barca, A.M., Sotelo-Mundo, R.R., Arteaga-Mackinney, G.E., Valenzuela-Melendez, M., & Peña-Ramos, E.A. (2013). Partial characterization of ultrafiltrated soy protein hydrolysates with antioxidant and free radical scavenging activities. Journal of Food Science, 78(8), C1152–C1158. doi:10.1111/1750-3841.12200
   PubMed Web of Science ®Google Scholar
• Kirchhoff, P.M., Biehl, B., & Crone, G. (1989). Peculiarity of the accumulation of free amino acids during cocoa fermentation. Food Chemistry, 31(4), 295–311. doi:10.1016/0308-8146(89)90071-X
   Web of Science ®Google Scholar
• Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the Head of Bacteriophage T4. Nature, 227, 680–685. doi:10.1038/227680a0
   PubMed Web of Science ®Google Scholar
• Lerceteau, E., Rogers, J., Petiard, V., & Crouzillat, D. (1999). Evolution of cocoa bean proteins during fermentation: a study two-dimensional electrophoresis. Journal of the Science of Food and Agriculture, 79(4), 619–625. doi:10.1002/(SICI)1097-0010(19990315)79:4<619::AID-JSFA230>3.0.CO;2-O
   Web of Science ®Google Scholar
• Lowry, O.H., Rosebrough, N.J., Farr, A.L., & Randall, R.J. (1951). Protein measurements with the Folin phenol reagent. The Journal of Biological Chemistry, 193(1), 265–275.
   PubMed Web of Science ®Google Scholar
• McDonald-Wicks, L.K., Wood, L.G., & Garg, M.L. (2006). Methodology for the determination of biological antioxidant capacity in vitro: a review. Journal of the Science and Food Agriculture, 86(13), 316–323. doi:10.1002/jsfa.2603
   Web of Science ®Google Scholar
• Preza, A.M., Jaramillo, M.E., Puebla, A.M., Mateos, J.C., Hernández, R., & Lugo, E. (2010). Antitumor activity against murine lymphoma L5178Y model of proteins from cacao (Theobroma cacao L.) seeds in relation with in vitro antioxidant activity. BMC-Complementary and Alternative Medicine, 10, 61. doi:10.1186/1472-6882-10-61
   PubMed Web of Science ®Google Scholar
• Ranamukhaarachchi, S., Meissner, L., & Moresoli, C. (2013). Production of antioxidant soy protein hydrolysates by sequential ultrafiltration and nanofiltration. Journal of Membrane Science, 429, 81–87. doi:10.1016/j.memsci.2012.10.040
   Web of Science ®Google Scholar
• Re, R., Pellegrini, N., Proteggente, A., Pannala, A., Yang, M., & Rice-Evans, C. (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine, 26, 1231–1237. doi:10.1016/S0891-5849(98)00315-3
   PubMed Web of Science ®Google Scholar
• Romero-Cortes, T., Salgado-Cervantes, M.A., García-Alamilla, P., García-Alvarado, M.A., Rodríguez-Jimenes, G.C., Hidalgo-Morales, M., & Robles-Olvera, V. (2013). Relationship between fermentation index and other biochemical changes evaluated during the fermentation of Mexican cocoa (Theobroma cacao) beans. Journal of the Science of Food and Agriculture, 93(10), 2596–2604. doi:10.1002/jsfa.6088
   PubMed Web of Science ®Google Scholar
• Rusconi, M., & Conti, A. (2010). Theobroma cacao L. the food of the gods: a scientific approach beyond myths and claims. Pharmacological Research, 61(1), 5–13. doi:10.1016/j.phrs.2009.08.008
   PubMed Web of Science ®Google Scholar
• Samaranayaka, A.G.P., & Li-Chan, E.C.Y. (2011). Food-derived peptidic antioxidants: A review of their production, assessment, and potential applications. Journal of Functional Foods, 3(4), 229–254. doi:10.1016/j.jff.2011.05.006
   Web of Science ®Google Scholar
• Sarmadi, B.H., & Ismail, A. (2010). Antioxidative peptides from food proteins: A review. Peptides, 31(10), 1949–1956. doi:10.1016/j.peptides.2010.06.020
   PubMed Web of Science ®Google Scholar
• Sarmadi, B.H., Ismail, A., & Hamid, M. (2011). Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of cocoa (Theobroma cacao L.) autolysates. Food Research International, 44(1), 290–296. doi:10.1016/j.foodres.2010.10.017
   Web of Science ®Google Scholar
• Schägger, H. (2006). Tricine-SDS-PAGE. Nature Protocols, 1, 16–22. doi:10.1038/nprot.2006.4
   PubMed Web of Science ®Google Scholar
• Soriano-Santos, J., & Escalona-Buendía, H. (2015). Angiotensin I-Converting Enzyme inhibitory and antioxidant activities and surfactant properties of protein hydrolysates as obtained of Amaranthus hypochondriacus L. grain. Journal of Food Science and Technology, 52(4), 2073–2082. doi:10.1007/s13197-013-1223-4
   PubMed Web of Science ®Google Scholar
• Tironi, V.A., & Añón, M.C. (2010). Amaranth proteins as a source of antioxidant peptides: Effect of proteolysis. Food Research International, 43(1), 315–322. doi:10.1016/j.foodres.2009.10.001
   Web of Science ®Google Scholar
• Valko, M., Leibfritz, D., Moncol, J., Cronin, M.T.D., Mazur, M., & Telser, J. (2007). Free radicals and antioxidants in normal physiological functions and human disease. The International Journal of Biochemistry & Cell Biology, 39(1), 44–84. doi:10.1016/j.biocel.2006.07.001
   PubMed Web of Science ®Google Scholar
• Voigt, J., & Biehl, B. (1993). The major seed proteins of Theobroma cacao L. Food Chemistry, 47(2), 145–151. doi:10.1016/0308-8146(93)90236-9
   Web of Science ®Google Scholar
• Wang, X., Zheng, X., Kopparapu, N., Cong, W., Deng, Y., Sun, X., & Liu, X. (2014). Purification and evaluation of a novel antioxidant peptide from corn protein hydrolysate. Process Biochemistry, 49(9), 1562–1569. doi:10.1016/j.procbio.2014.05.014
   Web of Science ®Google Scholar
• Zak, D.L., & Keeney, P.G. (1976). Changes in cocoa proteins during ripening of fruit, fermentation, and further processing of cocoa beans. Journal of Agricultural and Food Chemistry, 24(3), 483–486. doi:10.1021/jf60205a056
   PubMed Web of Science ®Google Scholar