1,927
Views
17
CrossRef citations to date
0
Altmetric
Original Research

Identification of a novel human memory T-cell population with the characteristics of stem-like chemo-resistance

, , , , , , , , , , , , , , & show all
Article: e1165376 | Received 13 Jan 2016, Accepted 08 Mar 2016, Published online: 08 Jun 2016

References

  • Mackall CL, Fleisher TA, Brown MR, Andrich MP, Chen CC, Feuerstein IM, Magrath IT, Wexler LH, Dimitrov DS, Gress RE. Distinctions between CD8+ and CD4+ T-cell regenerative pathways result in prolonged T-cell subset imbalance after intensive chemotherapy. Blood 1997; 89:3700-7; PMID:9160675
  • Ray-Coquard I, Cropet C, Van Glabbeke M, Sebban C, Le Cesne A, Judson I, Tredan O, Verweij J, Biron P, Labidi I et al. Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas. Cancer Res 2009; 69:5383-91; PMID:19549917; http://dx.doi.org/10.1158/0008-5472.CAN-08-3845
  • Neuenhahn M, Busch DH. The quest for CD8+ memory stem cells. Immunity 2009; 31:702-4; PMID:19932070; http://dx.doi.org/10.1016/j.immuni.2009.10.002
  • Turtle CJ, Swanson HM, Fujii N, Estey EH, Riddell SR. A distinct subset of self-renewing human memory CD8+ T cells survives cytotoxic chemotherapy. Immunity 2009; 31:834-44; PMID:19879163; http://dx.doi.org/10.1016/j.immuni.2009.09.015
  • Gattinoni L, Lugli E, Ji Y, Pos Z, Paulos CM, Quigley MF, Almeida JR, Gostick E, Yu Z, Carpenito C et al. A human memory T cell subset with stem cell-like properties. Nature medicine 2011; 17:1290-7; PMID:21926977; http://dx.doi.org/10.1038/nm.2446
  • Tsukahara T, Kawaguchi S, Torigoe T, Kimura S, Murase M, Ichimiya S, Wada T, Kaya M, Nagoya S, Ishii T et al. Prognostic impact and immunogenicity of a novel osteosarcoma antigen, papillomavirus binding factor, in patients with osteosarcoma. Cancer Sci 2008; 99:368-75; PMID:18271936; http://dx.doi.org/10.1111/j.1349-7006.2008.00695.x
  • Hirohashi Y, Torigoe T, Maeda A, Nabeta Y, Kamiguchi K, Sato T, Yoda J, Ikeda H, Hirata K, Yamanaka N et al. An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin. Clin Cancer Res 2002; 8:1731-9; PMID:12060610
  • Garderet L, Dulphy N, Douay C, Chalumeau N, Schaeffer V, Zilber MT, Lim A, Even J, Mooney N, Gelin C et al. The umbilical cord blood alphabeta T-cell repertoire: characteristics of a polyclonal and naive but completely formed repertoire. Blood 1998; 91:340-6; PMID:9414303
  • Zippelius A, Bioley G, Le Gal FA, Rufer N, Brandes M, Batard P, De Smedt M, Plum J, Speiser DE, Cerottini JC et al. Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J Immunol 2004; 172:2773-7; PMID:14978076; http://dx.doi.org/10.4049/jimmunol.172.5.2773
  • Guarda G, Hons M, Soriano SF, Huang AY, Polley R, Martin-Fontecha A, Stein JV, Germain RN, Lanzavecchia A, Sallusto F. L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells. Nat Immunol 2007; 8:743-52; PMID:17529983; http://dx.doi.org/10.1038/ni1469
  • Hikono H, Kohlmeier JE, Takamura S, Wittmer ST, Roberts AD, Woodland DL. Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells. J Exp Med 2007; 204:1625-36; PMID:17606632; http://dx.doi.org/10.1084/jem.20070322
  • Appay V, van Lier RA, Sallusto F, Roederer M. Phenotype and function of human T lymphocyte subsets: consensus and issues. Cytometry A 2008; 73:975-83; PMID:18785267; http://dx.doi.org/10.1002/cyto.a.20643
  • Resta R, Yamashita Y, Thompson LF. Ecto-enzyme and signaling functions of lymphocyte CD73. Immunol Rev 1998; 161:95-109; PMID:9553767; http://dx.doi.org/10.1111/j.1600-065X.1998.tb01574.x
  • Colgan SP, Eltzschig HK, Eckle T, Thompson LF. Physiological roles for ecto-5'-nucleotidase (CD73). Purinergic Signal 2006; 2:351-60; PMID:18404475; http://dx.doi.org/10.1007/s11302-005-5302-5
  • Dianzani U, Redoglia V, Bragardo M, Attisano C, Bianchi A, Di Franco D, Ramenghi U, Wolff H, Thompson LF, Pileri A et al. Co-stimulatory signal delivered by CD73 molecule to human CD45RAhiCD45ROlo (naive) CD8+ T lymphocytes. J Immunol 1993; 151:3961-70; PMID:7691935
  • Wang L, Fan J, Thompson LF, Zhang Y, Shin T, Curiel TJ, Zhang B. CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice. J Clin Invest 2011; 121:2371-82; PMID:21537079; http://dx.doi.org/10.1172/JCI45559
  • Peola S, Borrione P, Matera L, Malavasi F, Pileri A, Massaia M. Selective induction of CD73 expression in human lymphocytes by CD38 ligation: a novel pathway linking signal transducers with ecto-enzyme activities. J Immunol 1996; 157:4354-62; PMID:8906810
  • Thompson LF, Ruedi JM, O'Connor RD, Bastian JF. Ecto-5'-nucleotidase expression during human B cell development. An explanation for the heterogeneity in B lymphocyte ecto-5'-nucleotidase activity in patients with hypogammaglobulinemia. J Immunol 1986; 137:2496-500; PMID:3020125
  • Mandapathil M, Hilldorfer B, Szczepanski MJ, Czystowska M, Szajnik M, Ren J, Lang S, Jackson EK, Gorelik E, Whiteside TL. Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells. J Biol Chem 2010; 285:7176-86; PMID:19858205; http://dx.doi.org/10.1074/jbc.M109.047423
  • Sun X, Wu Y, Gao W, Enjyoji K, Csizmadia E, Muller CE, Murakami T, Robson SC. CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice. Gastroenterology 2010; 139:1030-40; PMID:20546740; http://dx.doi.org/10.1053/j.gastro.2010.05.007
  • Beavis PA, Stagg J, Darcy PK, Smyth MJ. CD73: a potent suppressor of antitumor immune responses. Trends Immunol 2012; 33:231-7; PMID:22487321; http://dx.doi.org/10.1016/j.it.2012.02.009
  • Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 2007; 204:1257-65; PMID:17502665; http://dx.doi.org/10.1084/jem.20062512
  • Zhang B. CD73: a novel target for cancer immunotherapy. Cancer Res 2010; 70:6407-11; PMID:20682793; http://dx.doi.org/10.1158/0008-5472.CAN-10-1544
  • Groom JR, Luster AD. CXCR3 in T cell function. Exp Cell Res 2011; 317:620-31; PMID:21376175; http://dx.doi.org/10.1016/j.yexcr.2010.12.017
  • Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998; 187:875-83; PMID:9500790; http://dx.doi.org/10.1084/jem.187.6.875
  • Kim CH, Rott L, Kunkel EJ, Genovese MC, Andrew DP, Wu L, Butcher EC. Rules of chemokine receptor association with T cell polarization in vivo. J Clin Invest 2001; 108:1331-9; PMID:11696578; http://dx.doi.org/10.1172/JCI13543
  • Xie JH, Nomura N, Lu M, Chen SL, Koch GE, Weng Y, Rosa R, Di Salvo J, Mudgett J, Peterson LB et al. Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation. J Leukoc Biol 2003; 73:771-80; PMID:12773510; http://dx.doi.org/10.1189/jlb.1102573
  • Havenith SH, Yong SL, Henson SM, Piet B, Idu MM, Koch SD, Jonkers RE, Kragten NA, Akbar AN, van Lier RA et al. Analysis of stem-cell-like properties of human CD161++IL-18Ralpha+ memory CD8+ T cells. Int Immunol 2012; 24:625-36; PMID:22836020; http://dx.doi.org/10.1093/intimm/dxs069
  • Fuertes Marraco SA, Soneson C, Cagnon L, Gannon PO, Allard M, Abed Maillard S, Montandon N, Rufer N, Waldvogel S, Delorenzi M et al. Long-lasting stem cell-like memory CD8+ T cells with a naive-like profile upon yellow fever vaccination. Sci Transl Med 2015; 7:282ra48; PMID:25855494; http://dx.doi.org/10.1126/scitranslmed.aaa3700
  • Bleakley M, Heimfeld S, Loeb KR, Jones LA, Chaney C, Seropian S, Gooley TA, Sommermeyer F, Riddell SR, Shlomchik WD. Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts. J Clin Invest 2015; 125:2677-89; PMID:26053664; http://dx.doi.org/10.1172/JCI81229