Ligand–receptor dissociated expression explains high TSLP without prognostic impact in human primary head and neck squamous cell carcinoma

References

• Shikotra A, Choy DF, Ohri CM, Doran E, Butler C, Hargadon B, Shelley M, Abbas AR, Austin CD, Jackman J et al. Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol 2012; 129:104-11.e1–9; PMID:22664159; http://dx.doi.org/10.1016/j.jaci.2011.08.031
   PubMed Web of Science ®Google Scholar
• Soumelis V, Reche PA, Kanzler H, Yuan W, Edward G, Homey B, Gilliet M, Ho S, Antonenko S, Lauerma A et al. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 2002; 3:673-80; PMID:12055625; http://dx.doi.org/10.1038/nrm910
   PubMed Web of Science ®Google Scholar
• Ying S, O'Connor B, Ratoff J, Meng Q, Mallett K, Cousins D, Robinson D, Zhang G, Zhao J, Lee TH et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol Baltim Md 1950 2005; 174:8183-90; PMID:15944327; http://dx.doi.org/10.4049/jimmunol.174.12.8183
   Google Scholar
• Oyoshi MK, Larson RP, Ziegler SF, Geha RS. Mechanical injury polarizes skin dendritic cells to elicit a T(H)2 response by inducing cutaneous thymic stromal lymphopoietin expression. J Allergy Clin Immunol 2010; 126:976-84, 984.e1-5; PMID:21050944; http://dx.doi.org/10.1016/j.jaci.2010.08.041
   PubMed Web of Science ®Google Scholar
• Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M-H, Bogiatzi SI, Fernandez MI, Touzot M, Bichet J-C, Reyal F et al. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis. J Allergy Clin Immunol 2014; 134:373-81; PMID:24910175; http://dx.doi.org/10.1016/j.jaci.2014.04.022
   PubMed Web of Science ®Google Scholar
• Pandey A, Ozaki K, Baumann H, Levin SD, Puel A, Farr AG, Ziegler SF, Leonard WJ, Lodish HF. Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol 2000; 1:59-64; PMID:10881176; http://dx.doi.org/10.1038/76923
   PubMed Web of Science ®Google Scholar
• Park LS, Martin U, Garka K, Gliniak B, Di Santo JP, Muller W, Largaespada DA, Copeland NG, Jenkins NA, Farr AG et al. Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor. J Exp Med 2000; 192:659-70; PMID:10974032; http://dx.doi.org/10.1084/jem.192.5.659
   PubMed Web of Science ®Google Scholar
• Reche PA, Soumelis V, Gorman DM, Clifford T, Liu Mr null, Travis M, Zurawski SM, Johnston J, Liu YJ, Spits H et al. Human thymic stromal lymphopoietin preferentially stimulates myeloid cells. J Immunol Baltim Md 1950 2001; 167:336-43; PMID:11418668; http://dx.doi.org/10.4049/jimmunol.167.1.336
   Google Scholar
• Gilliet M, Soumelis V, Watanabe N, Hanabuchi S, Antonenko S, de Waal-Malefyt R, Liu Y-J. Human dendritic cells activated by TSLP and CD40L induce proallergic cytotoxic T cells. J Exp Med 2003; 197:1059-63; PMID:12707303; http://dx.doi.org/10.1084/jem.20030240
   PubMed Web of Science ®Google Scholar
• Liu Y-J, Soumelis V, Watanabe N, Ito T, Wang Y-H, Malefyt R de W, Omori M, Zhou B, Ziegler SF. TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. Annu Rev Immunol 2007; 25:193-219; PMID:17129180; http://dx.doi.org/10.1146/annurev.immunol.25.022106.141718
   PubMed Web of Science ®Google Scholar
• Soumelis V, Liu Y-J. Human thymic stromal lymphopoietin: a novel epithelial cell-derived cytokine and a potential key player in the induction of allergic inflammation. Springer Semin Immunopathol 2004; 25:325-33; PMID:14999427; http://dx.doi.org/10.1007/s00281-003-0152-0
   PubMed Web of Science ®Google Scholar
• Ziegler SF, Liu Y-J. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat Immunol 2006; 7:709-14; PMID:16785889; http://dx.doi.org/10.1038/ni1360
   PubMed Web of Science ®Google Scholar
• De Monte L, Reni M, Tassi E, Clavenna D, Papa I, Recalde H, Braga M, Di Carlo V, Doglioni C, Protti MP. Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J Exp Med 2011; 208:469-78; PMID:21339327; http://dx.doi.org/10.1084/jem.20101876
   PubMed Web of Science ®Google Scholar
• Olkhanud PB, Rochman Y, Bodogai M, Malchinkhuu E, Wejksza K, Xu M, Gress RE, Hesdorffer C, Leonard WJ, Biragyn A. Thymic stromal lymphopoietin is a key mediator of breast cancer progression. J Immunol 2011; 186:5656-62; PMID:21490155; http://dx.doi.org/10.4049/jimmunol.1100463
   PubMed Web of Science ®Google Scholar
• Pedroza-Gonzalez A, Xu K, Wu T-C, Aspord C, Tindle S, Marches F, Gallegos M, Burton EC, Savino D, Hori T et al. Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J Exp Med 2011; 208:479-90; PMID:21339324; http://dx.doi.org/10.1084/jem.20102131
   PubMed Web of Science ®Google Scholar
• Wu T-C, Xu K, Banchereau R, Marches F, Yu CI, Martinek J, Anguiano E, Pedroza-Gonzalez A, Snipes GJ, O'Shaughnessy J et al. Reprogramming tumor-infiltrating dendritic cells for CD103+ CD8+ mucosal T-cell differentiation and breast cancer rejection. Cancer Immunol Res 2014; 2:487-500; PMID:24795361; http://dx.doi.org/10.1158/2326-6066.CIR-13-0217
   PubMed Web of Science ®Google Scholar
• DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, Coussens LM. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009; 16:91-102; PMID:19647220; http://dx.doi.org/10.1016/j.ccr.2009.06.018
   PubMed Web of Science ®Google Scholar
• Tatsumi T, Kierstead LS, Ranieri E, Gesualdo L, Schena FP, Finke JH, Bukowski RM, Mueller-Berghaus J, Kirkwood JM, Kwok WW et al. Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma. J Exp Med 2002; 196:619-28; PMID:12208877; http://dx.doi.org/10.1084/jem.20012142
   PubMed Web of Science ®Google Scholar
• Di Piazza M, Nowell CS, Koch U, Durham A-D, Radtke F. Loss of cutaneous TSLP-dependent immune responses skews the balance of inflammation from tumor protective to tumor promoting. Cancer Cell 2012; 22:479-93; PMID:23079658; http://dx.doi.org/10.1016/j.ccr.2012.08.016
   PubMed Web of Science ®Google Scholar
• Demehri S, Turkoz A, Manivasagam S, Yockey LJ, Turkoz M, Kopan R. Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin. Cancer Cell 2012; 22:494-505; PMID:23079659; http://dx.doi.org/10.1016/j.ccr.2012.08.017
   PubMed Web of Science ®Google Scholar
• Demehri S, Cunningham TJ, Manivasagam S, Ngo KH, Moradi Tuchayi S, Reddy R, Meyers MA, DeNardo DG, Yokoyama WM. Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis. J Clin Invest 2016; 126:1458-70; PMID:26927668; http://dx.doi.org/10.1172/JCI83724
   PubMed Web of Science ®Google Scholar
• Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010; 60:277-300; PMID:20610543; http://dx.doi.org/10.3322/caac.20073
   PubMed Web of Science ®Google Scholar
• Zhong J, Pandey A. Site-directed mutagenesis reveals a unique requirement for tyrosine residues in IL-7Ralpha and TSLPR cytoplasmic domains in TSLP-dependent cell proliferation. BMC Immunol 2010; 11:5; PMID:20144186; http://dx.doi.org/10.1186/1471-2172-11-5
   PubMed Web of Science ®Google Scholar
• Lu N, Wang Y-H, Wang Y-H, Arima K, Hanabuchi S, Liu Y-J. TSLP and IL-7 use two different mechanisms to regulate human CD4+ T cell homeostasis. J Exp Med 2009; 206:2111-9; PMID:19770269; http://dx.doi.org/10.1084/jem.20090153
   PubMed Web of Science ®Google Scholar
• Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M-H, Bogiatzi SI, Fernandez MI, Touzot M, Bichet J-C, Reyal F et al. Thymic stromal lymphopoietin links keratinocytes and dendritic cell–derived IL-23 in patients with psoriasis. J Allergy Clin Immunol 2014; 134:373-81.e4; PMID:24910175; http://dx.doi.org/10.1016/j.jaci.2014.04.022
   PubMed Web of Science ®Google Scholar
• Liu Y-J. Thymic stromal lymphopoietin: master switch for allergic inflammation. J Exp Med 2006; 203:269-73; PMID:16432252; http://dx.doi.org/10.1084/jem.20051745
   PubMed Web of Science ®Google Scholar
• Sun M, Tan W, Liu S, Liu G, Zhang X, Wang N, Qu X, Wei F. In situ expression and serum level of thymic stromal lymphopoietin in oral lichen planus. J Oral Pathol Med Off Publ Int Assoc Oral Pathol Am Acad Oral Pathol 2014; 43(10):740-5; PMID:24931732; http://dx.doi.org/10.1111/jop.12196
   Google Scholar
• Lee H-C, Headley MB, Loo Y-M, Berlin A, Gale M, Debley JS, Lukacs NW, Ziegler SF. Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection. J Allergy Clin Immunol 2012; 130:1187-96.e5; PMID:22981788; http://dx.doi.org/10.1016/j.jaci.2012.07.031
   PubMed Web of Science ®Google Scholar
• Feng Q, Wei H, Morihara J, Stern J, Yu M, Kiviat N, Hellstrom I, Hellstrom KE. Th2 type inflammation promotes the gradual progression of HPV-infected cervical cells to cervical carcinoma. Gynecol Oncol 2012; 127:412-9; PMID:22828962; http://dx.doi.org/10.1016/j.ygyno.2012.07.098
   PubMed Web of Science ®Google Scholar
• Nakamura Y, Miyata M, Ohba T, Ando T, Hatsushika K, Suenaga F, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H et al. Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation. J Allergy Clin Immunol 2008; 122:1208-14; PMID:18926564; http://dx.doi.org/10.1016/j.jaci.2008.09.022
   PubMed Web of Science ®Google Scholar
• Bogiatzi SI, Guillot-Delost M, Cappuccio A, Bichet J-C, Chouchane-Mlik O, Donnadieu M-H, Barillot E, Hupé P, Chlichlia K, Efremidou EI et al. Multiple-checkpoint inhibition of thymic stromal lymphopoietin-induced TH2 response by TH17-related cytokines. J Allergy Clin Immunol 2012; 130:233-40.e5; PMID:22664159; http://dx.doi.org/10.1016/j.jaci.2012.04.038
   PubMed Web of Science ®Google Scholar