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Research Article

Geniposide protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via up-regulation of miR-145-5p

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Pages 2875-2881 | Received 10 Apr 2019, Accepted 23 May 2019, Published online: 15 Jul 2019

References

  • Levin SN, Lyons JL. HIV and spinal cord disease. Handb Clin Neurol. 2018;152:213–227.
  • Held KS, Lane TE. Spinal cord injury, immunodepression, and antigenic challenge. Semin Immunol. 2014;26:415–420.
  • Hossain MS, Islam MS, Rahman MA, et al. Health status, quality of life and socioeconomic situation of people with spinal cord injuries six years after discharge from a hospital in Bangladesh. Spinal Cord. 2019. doi:10.1038/s41393-019-0261-9
  • Zhang Q, Yang H, An J, et al. Therapeutic effects of traditional Chinese medicine on spinal cord injury: a promising supplementary treatment in future. Evid Based Complement Alternat Med eCAM. 2016;2016:1.
  • Cheng S, Zhou F, Xu Y, et al. Geniposide regulates the miR-101/MKP-1/p38 pathway and alleviates atherosclerosis inflammatory injury in ApoE(-/-) mice. Immunobiology 2018;224:296–306.
  • Yang SQ, Chen YD, Li H, et al. Geniposide and gentiopicroside suppress hepatic gluconeogenesis via regulation of AKT-FOXO1 pathway. Arch Med Res. 2018;49:314–322.
  • Li N, Zhou H, Ma ZG, et al. Geniposide alleviates isoproterenol-induced cardiac fibrosis partially via SIRT1 activation in vivo and in vitro. Front Pharmacol. 2018;9:854.
  • Lu W, Zhao Y, Kong Y, et al. Geniposide prevents H2O2-induced oxidative damage in melanocytes by activating the PI3K-Akt signalling pathway. Clin Exp Dermatol. 2018;43:667–674.
  • Ma J, Ding Y. Geniposide suppresses growth, migration and invasion of MKN45 cells by down-regulation of lncRNA HULC. Exp Mol Pathol. 2018;105:252–259.
  • Chang CH, Wu JB, Yang JS, et al. The suppressive effects of geniposide and genipin on Helicobacter pylori infections in vitro and in vivo. J Food Sci. 2017;82:3021–3028.
  • Cheng F, Ma C, Sun L, et al. Synergistic neuroprotective effects of Geniposide and ursodeoxycholic acid in hypoxia-reoxygenation injury in SH-SY5Y cells. Exp Ther Med. 2018;15:320–326.
  • Yuan Y, Zheng Z. Geniposide protects PC-12 cells against oxygen and glucose deprivation-induced injury by up-regulation of long-noncoding RNA H19. Life Sci. 2019;216:176–182.
  • Li F, Zhou MW. MicroRNAs in contusion spinal cord injury: pathophysiology and clinical utility. Acta Neurol Belg. 2019;119:21–27.
  • Wang J, Masika J, Zhou J, et al. Traditional Chinese medicine baicalin suppresses mESCs proliferation through inhibition of miR-294 expression. Cell Physiol Biochem. 2015;35:1868–1876.
  • Chu SF, Zhang Z, Zhou X, et al. Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway. Acta Pharmacol Sin. 2019;40:13–25.
  • Zuberi M, Mir R, Khan I, et al. The promising signatures of circulating microRNA-145 in epithelial ovarian cancer patients. MicroRNA. 2019. doi:10.2174/2211536608666190225111234
  • Ye D, Shen Z, Zhou S. Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment. CMAR. 2019;11:969–979.
  • Wang CY, Yang SH, Tzeng SF. MicroRNA-145 as one negative regulator of astrogliosis. Glia. 2015;63:194–205.
  • De Gasperi R, Graham ZA. The signature of microRNA dysregulation in muscle paralyzed by spinal cord injury includes downregulation of microRNAs that target myostatin signaling. PLoS One. 2016;11:e0166189.
  • Li G, Chen T, Zhu Y, et al. MiR-103 alleviates autophagy and apoptosis by regulating SOX2 in LPS-injured PC12 cells and SCI rats. Iran J Basic Med Sci. 2018;21:292–300.
  • Zhong F, Xu J, Yang X, et al. miR-145 eliminates lipopolysaccharides-induced inflammatory injury in human fibroblast-like synoviocyte MH7A cells. J Cell Biochem. 2018;119:10059–10066.
  • Su Q, Yao J, Sheng C. Geniposide attenuates LPS-induced injury via up-regulation of miR-145 in H9c2 cells. Inflammation. 2018;41:1229–1237.
  • Greene LA, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA. 1976;73:2424–2428.
  • Westerink RH, Ewing AG. The PC12 cell as model for neurosecretion. Acta Physiol. 2007;192:273–285..
  • Zhang Z, Wang X, Zhang D, et al. Geniposide-mediated protection against amyloid deposition and behavioral impairment correlates with downregulation of mTOR signaling and enhanced autophagy in a mouse model of Alzheimer's disease. Aging. 2019;11:536–548.
  • Ma ZG, Kong CY, Song P, et al. Geniposide protects against obesity-related cardiac injury through AMPKalpha- and Sirt1-dependent mechanisms. Oxid Med Cell Longev. 2018;2018:6053727.
  • Peng JH, Leng J, Tian HJ, et al. Geniposide and chlorogenic acid combination ameliorates non-alcoholic steatohepatitis involving the protection on the gut barrier function in mouse induced by high-fat diet. Front Pharmacol. 2018;9:1399.
  • Kosik KS. The neuronal microRNA system. Nat Rev Neurosci. 2006;7:911–920. Dec PubMed PMID: 17115073; eng.
  • Eacker SM, Dawson TM, Dawson VL. The interplay of microRNA and neuronal activity in health and disease. Front Cell Neurosci. 2013;7:136.
  • Karova K, Wainwright JV, Machova-Urdzikova L, et al. Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-kappaB pathway inhibition. J Neuroinflammation. 2019;16:12.
  • Kasuya Y, Umezawa H, Hatano M. Stress-activated protein kinases in spinal cord injury: focus on roles of p38. IJMS. 2018;19:867.
  • Srinivasan M, Bayon B, Chopra N, et al. Novel nuclear factor-kappaB targeting peptide suppresses beta-amyloid induced inflammatory and apoptotic responses in neuronal cells. PLoS One 2016;11:e0160314.
  • Kumar A, Singh UK, Kini SG, et al. JNK pathway signaling: a novel and smarter therapeutic targets for various biological diseases. Future Medicinal Chemistry. 2015;7:2065–2086.
  • Kanigur Sultuybek G, Soydas T, Yenmis G. NF-kappaB as the mediator of metformin's effect on aging and age-related diseases. Clin Exp Pharmacol Physiol. 2019;46:413–422.
  • Yu B, Shen Y, Qiao J, et al. Geniposide attenuates Staphylococcus aureus-induced pneumonia in mice by inhibiting NF-kappaB activation. Microb Pathog. 2017;112:117–121.
  • Li F, Dai M, Wu H, et al. Immunosuppressive effect of geniposide on mitogen-activated protein kinase signalling pathway and their cross-talk in fibroblast-like synoviocytes of adjuvant arthritis rats. Molecules. 2018;23:E91.