Lidocaine inhibits proliferation and metastasis of lung cancer cell via regulation of miR-539/EGFR axis

Reference

• Torre LA, Siegel RL, Jemal A. Lung cancer statistics. Adv Exp Med Biol. 2016;893:1–19.
   PubMed Web of Science ®Google Scholar
• Bryan DS, Donington JS. The role of surgery in management of locally advanced non-small cell lung cancer. Curr Treat Options in Oncol. 2019;20:27.
   PubMed Web of Science ®Google Scholar
• Azar FE, Azami-Aghdash S, Pournaghi-Azar F, et al. Cost-effectiveness of lung cancer screening and treatment methods: a systematic review of systematic reviews. BMC Health Serv Res. 2017;17:413.
   PubMed Web of Science ®Google Scholar
• Beecham GB, Stephenson E. Lidocaine. Treasure Island (FL): StatPearls Publishing LLC; 2019.
   Google Scholar
• Yang X, Yang LX, Wu J, et al. Treatment of lidocaine on subacute thyroiditis via restraining inflammatory factor expression and inhibiting pyroptosis pathway. J Cell Biochem. 2019, [Epub ahead of print]. doi:10.1002/jcb.27675
   Web of Science ®Google Scholar
• Sisti MS, Nishida F, Zanuzzi CN, et al. Lidocaine protects neurons of the spinal cord in an excitotoxicity model. Neurosci Lett. 2019;698:105–112.
   PubMed Web of Science ®Google Scholar
• Mitchell SJ, Merry AF, Frampton C, et al. Cerebral protection by lidocaine during cardiac operations: a follow-up study. Ann Thoracic Surg. 2009;87:820–825.
   PubMed Web of Science ®Google Scholar
• Wang L, Wang M, Li S, et al. Nebulized lidocaine ameliorates allergic airway inflammation via downregulation of TLR2. Mol Immunol. 2018;97:94–100.
   PubMed Web of Science ®Google Scholar
• Li J, Zhu X, Yang S, et al. Lidocaine attenuates cognitive impairment after isoflurane anesthesia by reducing mitochondrial damage. Neurochem Res. 2019;44:1703. Apr 15.
   PubMed Web of Science ®Google Scholar
• Tat T, Jurj A, Selicean C, et al. Antiproliferative effects of propofol and lidocaine on the colon adenocarcinoma microenvironment. J BUON. 2019;24:106–115.
   PubMed Web of Science ®Google Scholar
• Sui H, Lou A, Li Z, et al. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. BMC Cancer. 2019;19:233.
   PubMed Web of Science ®Google Scholar
• D'Agostino G, Saporito A, Cecchinato V, et al. Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration. Br J Anaesth. 2018;121:962–968.
   PubMed Web of Science ®Google Scholar
• Yang Q, Zhang Z, Xu H, et al. Lidocaine alleviates cytotoxicity-resistance in lung cancer A549/DDP cells via down-regulation of miR-21. Mol Cell Biochem. 2019;456:63–72. Jan 14.
   PubMed Web of Science ®Google Scholar
• Zhang L, Hu R, Cheng Y, et al. Lidocaine inhibits the proliferation of lung cancer by regulating the expression of GOLT1A. Cell Prolif. 2017;50. doi:10.1111/cpr.12364
   Web of Science ®Google Scholar
• Seitz H, Royo H, Bortolin ML, et al. A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res. 2004;14:1741–1748.
   PubMed Web of Science ®Google Scholar
• Gong YB, Fan XH. MiR-539-3p promotes the progression of epithelial ovarian cancer by targeting SPARCL1. Eur Rev Med Pharmacol Sci. 2019;23:2366–2373.
   PubMed Web of Science ®Google Scholar
• Su H, Wang X, Song J, et al. MicroRNA-539 inhibits the progression of Wilms' tumor through downregulation of JAG1 and Notch1/3. CBM. 2019;24:125–133.
   Web of Science ®Google Scholar
• Zhao J, Xu J, Zhang R. MicroRNA-539 inhibits colorectal cancer progression by directly targeting SOX4. Oncol Lett. 2018;16:2693–2700.
   PubMed Web of Science ®Google Scholar
• Deng H, Qianqian G, Ting J, et al. miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1. Biomed Pharmacother. 2018;106:1072–1081.
   PubMed Web of Science ®Google Scholar
• Liu X, Wang P, Zhang C, et al. Epidermal growth factor receptor (EGFR): a rising star in the era of precision medicine of lung cancer. Oncotarget. 2017;8:50209–50220.
   PubMedGoogle Scholar
• Guo J, Gong G, Zhang B. miR-539 acts as a tumor suppressor by targeting epidermal growth factor receptor in breast cancer. Sci Rep. 2018;8:2073.
   PubMed Web of Science ®Google Scholar
• Qu X, Yang L, Shi Q, et al. Lidocaine inhibits proliferation and induces apoptosis in colorectal cancer cells by upregulating mir-520a-3p and targeting EGFR. Pathol Res Practice. 2018;214:1974–1979.
   PubMed Web of Science ®Google Scholar
• Jiang Y, Gou H, Zhu J, et al. Lidocaine inhibits the invasion and migration of TRPV6-expressing cancer cells by TRPV6 downregulation. Oncol Lett. 2016;12:1164–1170.
   PubMed Web of Science ®Google Scholar
• Rancan L, Simon C, Marchal-Duval E, et al. Lidocaine administration controls microRNAs alterations observed after lung ischemia-reperfusion injury. Anesth Analg. 2016;123:1437–1447.
   PubMed Web of Science ®Google Scholar
• Sung SH, Lee JG, Yu SB, et al. The effects of lidocaine and procaine on microRNA expression of adipocyte-derived adult stem cells. Korean J Anesthesiol. 2012;62:552–557.
   PubMedGoogle Scholar
• Wang Y, Xie J, Liu W, et al. Lidocaine sensitizes the cytotoxicity of 5-fluorouacil in melanoma cells via upregulation of microRNA-493. Pharmazie. 2017;72:663–669.
   PubMed Web of Science ®Google Scholar
• Wang Q, She Y, Bi X, et al. Dexmedetomidine protects PC12 cells from lidocaine-induced cytotoxicity through downregulation of COL3A1 mediated by miR-let-7b. DNA Cell Biol. 2017;36:518–528.
   PubMed Web of Science ®Google Scholar
• Holowka D, Baird B. Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis. Biochim Biophys Acta Biomembr. 2017;1859:1430–1435.
   PubMed Web of Science ®Google Scholar
• Iyer S, Prajapati R, Ramesh A, et al. The future of lung cancer therapy: striding beyond conventional EGFR and ALK treatments. Mol Clin Onc. 2019;10:469–475.
   PubMed Web of Science ®Google Scholar
• Belo A, Cheng K, Chahdi A, et al. Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion. Am J Physiol Gastrointest Liver Physiol. 2011;300:G749–60.
   PubMed Web of Science ®Google Scholar
• Xie G, Cheng K, Shant J, et al. Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells. Am J Physiol Gastrointest Liver Physiol. 2009;296:G755–63.
   PubMed Web of Science ®Google Scholar
• Wang H, Yu Z, Huo S, et al. Overexpression of ELF3 facilitates cell growth and metastasis through PI3K/Akt and ERK signaling pathways in non-small cell lung cancer. Int J Biochem Cell Biol. 2018;94:98–106.
   PubMed Web of Science ®Google Scholar
• Chen J, Jiao Z. Lidocaine inhibits melanoma cell proliferation by regulating ERK phosphorylation. J Cell Biochem. 2019;120:6402–6408.
   PubMed Web of Science ®Google Scholar