5
Views
4
CrossRef citations to date
0
Altmetric
(RG) Obstetrics and Gynaecology

Acute effects of tibolone on cerebral vascular reactivity in vitro

, , , &
Pages 228-237 | Published online: 03 Jul 2009

References

  • Mosca L, Manson JE, Sutherland SE, Langer RD, Manolio T, Barrett-Connor E. Cardiovascular disease in women: a statement for healthcare pro-fessionals from the American Heart Association. Writing Group. Circulation 1997;96:2468–82
  • Manolio TA, Kronmal RA, Burke GL, O'Leary DH, Price TR. Short-term predictors of incident stroke in older adults. The Cardiovascular Health Study. Stroke 1996;27:1479–86
  • Paganini-Hill A. Hormone replacement therapy and stroke: risk, protection or no effect? Maturitas 2001;38:243–61
  • Pedersen AT, Lidegaard O, Kreiner S, Ottesen B. Hormone replacement therapy and risk of non-fatal stroke. Lancet 1997;350:1277–83
  • Grodstein F, Manson JE, Colditz GA, Willett WC, Speizer FE, Stampfer MJ. A pros-pective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med 2000;133:933–41
  • Penotti M, Farina M, Sironi L, Barletta L, Gabrielli L, Vignali M. Cerebral artery blood flow in relation to age and menopausal status. Obstet Gynecol 1996;88:106–9
  • Penotti M, Sironi L, Miglierina L, et al. The effect of tamoxifen and transdermal 170-estradiol on cerebral arterial vessels: a randomized controlled study. Am J Obstet Gynecol 1998; 178:801–5
  • Skarsgard P, van Breemen C, Laher I. Estrogen regulates myogenic tone in pressurized cerebral arteries by enhanced basal release of nitric oxide. Am J Physiol 1997;273:H2248–56
  • Ghanam K, Javellaud J, Ea-Kim L, Oudart N. Effects of treatment with 170-estradiol on the hypercholesterolemic rabbit middle cerebral artery. Maturitas 2000;34: 249–60
  • Pelligrino DA, Santizo R, Baughman VL, Wang Q. Cerebral vasodilating capacity during forebrain ischemia: effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase. Neuroreport 1998;9: 3285–91
  • Yang SH, Shi J, Day AL, Simpkins JW. Estradiol exerts neuroprotective effects when administered after ischemic insult. Stroke 2000;31:745–9
  • Kitazawa T, Hamada E, Kitazawa K, Gaznabi AK. Non-genomic mechanism of 170-oestradiol-induced inhibition of contraction in mammalian vascular smooth muscle. J Physiol 1997;499:497–511
  • Jiang CW, Sarrel PM, Lindsay DC, Poole-Wilson PA, Collins P. Endothelium-independent relax-ation of rabbit coronary artery by 170-oestradiol in vitro. Br J Pharmacol 1991;104: 1033–7
  • Salom JB, Burguete MC, Perez-Asensio FJ, Torregrosa G, Alborch E. Relaxant effects of 170-estradiol in cerebral arteries through Ca(2+) entry inhibition. J Cereb Blood Flow Metab 2001;21: 422–9
  • Ogata R, Inoue Y, Nakano H, Ito Y, Kitamura K. Oestradiol-induced relaxation of rabbit basilar artery by inhibition of voltage-dependent Ca channels through GTP-binding protein. Br J Pharmacol 1996;117:351–9
  • White RE, Darkow DJ, Lang JL. Estrogen relaxes coronary arteries by opening BKCa channels through a cGMP-dependent mechanism. Circ Res 1995;77:936–42
  • Otter D, Austin C. Effects of 170-oestradiol on rat isolated coronary and mesenteric artery tone: involvement of nitric oxide. J Pharm Pharmacol 1998;50:531–8
  • Bucci M, Roviezzo F, Cicala C, Pinto A, Cirino G. 170-0estradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism. Br J Pharmacol 2002; 135:1695–700
  • Albertazzi P, Di Micco R, Zanardi E. Tibolone: a review. Maturitas 1998;30:295–305
  • Bjarnason NH, Bjarnason K, Haarbo J, Rosenquist C, Christiansen C. Tibolone: preven-tion of bone loss in late postmenopausal women. J Clin Endocrinol Metab 1996;81:2419–22
  • Kloosterboer HJ. Tibolone: a steroid with a tissue-specific mode of action. J Steroid Biochem Mol Biol 2001;76:231–8
  • Zoma W, Baker RS, Lang U, Clark KE. Hemo-dynamic response to tibolone in reproductive and nonreproductive tissues in the sheep. Am J Obstet Gynecol 2001;184:544–51
  • Grady D, Herrington D, Bittner V, et al. Cardio-vascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). J Am Med Assoc 2002;288: 49–57
  • Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. J Am Med Assoc 2002;288:321–33
  • Mulvany MJ, Halpern W. Contractile properties of small arterial resistance vessels in spontane-ously hypertensive and normotensive rats. Circ Res 1977;41:19–26
  • Littleton-Kearney MT, Agnew DM, Traystman RJ, Hum PD. Effects of estrogen on cerebral blood flow and pial microvasculature in rabbits. Am J Physiol Heart Circ Physiol 2000;279: H1208–14
  • Figtree GA, Lu Y, Webb CM, Collins P. Raloxifene acutely relaxes rabbit coronary arter-ies in vitro by an estrogen receptor-dependent and nitric oxide-dependent mechanism. Circulation 1999;100:1095–101
  • Dalsgaard T, Larsen CR, Mortensen A, Larsen JJ, Ottesen B. New animal model for the study of postmenopausal coronary and cerebral artery function: the Watanabe heritable hyperlipidemic rabbit fed on a diet avoiding phytoestrogens. Climacteric 2002;5:178–89
  • Shaul PW. Rapid activation of endothelial nitric oxide synthase by estrogen. Steroids 1999;64: 28–34
  • Rosenfeld CR, Cox BE, Roy T, Magness RR. Nitric oxide contributes to estrogen-induced vasodilation of the ovine uterine circulation. J Clin Invest 1996;98:2158–66
  • Chen Z, Yuhanna IS, Galcheva-Gargova Z, Karas RH, Mendelsohn ME, Shaul PW. Estrogen receptor a mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen. J Clin Invest 1999;103:401–6
  • Chambliss KL, Yuhanna IS, Anderson RG, Mendelsohn ME, Shaul PW. ERB has non-genomic action in caveolae. Mol Endocrinol 2002;16:938–46
  • Murphy JG, Khalil RA. Decreased [CA(2+)](i) during inhibition of coronary smooth muscle contraction by 17B-estradiol, progesterone, and testosterone. J Pharmacol Exp Ther 1999;291: 44–52
  • Song J, Standley PR, Zhang F, et al. Tamoxifen (estrogen antagonist) inhibits voltage-gated calcium current and contractility in vascular smooth muscle from rats. J Pharmacol Exp Ther 1996;277:1444–53
  • Standen NB, Quayle JM. channel modulation in arterial smooth muscle. Acta Physiol Scand 1998;164:549–57

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.