ATP-Dependent Recruitment of Export Factor Aly/REF onto Intronless mRNAs by RNA Helicase UAP56

REFERENCES

• Abruzzi, K. C., S. Lacadie, and M. Rosbash. 2004. Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes. EMBO J. 23:2620–2631.
   PubMed Web of Science ®Google Scholar
• Battle, D. J., M. Kasim, J. Yong, F. Lotti, C. K. Lau, J. Mouaikel, Z. Zhang, K. Han, L. Wan, and G. Dreyfuss. 2006. The SMN complex: an assembly machine for RNPs. Cold Spring Harbor Symp. Quant. Biol. 71:313–320.
   PubMedGoogle Scholar
• Cheng, H., K. Dufu, C. S. Lee, J. L. Hsu, A. Dias, and R. Reed. 2006. Human mRNA export machinery recruited to the 5′ end of mRNA. Cell 127:1389–1400.
   PubMed Web of Science ®Google Scholar
• Cordin, O., J. Banroques, N. K. Tanner, and P. Linder. 2006. The DEAD-box protein family of RNA helicases. Gene 367:17–37.
   PubMed Web of Science ®Google Scholar
• Cullen, B. R. 2003. Nuclear RNA export. J. Cell Sci. 116:587–597.
   PubMed Web of Science ®Google Scholar
• Erkmann, J. A., R. Sanchez, N. Treichel, W. F. Marzluff, and U. Kutay. 2005. Nuclear export of metazoan replication-dependent histone mRNAs is dependent on RNA length and is mediated by TAP. RNA 11:45–58.
   PubMed Web of Science ®Google Scholar
• Fleckner, J., M. Zhang, J. Valcarcel, and M. R. Green. 1997. U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. Genes Dev. 11:1864–1872.
   PubMed Web of Science ®Google Scholar
• Gatfield, D., and E. Izaurralde. 2002. REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J. Cell Biol. 159:579–588.
   PubMed Web of Science ®Google Scholar
• Gatfield, D., H. Le Hir, C. Schmitt, I. C. Braun, T. Kocher, M. Wilm, and E. Izaurralde. 2001. The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila. Curr. Biol. 11:1716–1721.
   PubMedGoogle Scholar
• Gruter, P., C. Tabernero, C. von Kobbe, C. Schmitt, C. Saavedra, A. Bachi, M. Wilm, B. K. Felber, and E. Izaurralde. 1998. TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol. Cell 1:649–659.
   PubMed Web of Science ®Google Scholar
• Herold, A., L. Teixeira, and E. Izaurralde. 2003. Genome-wide analysis of nuclear mRNA export pathways in Drosophila. EMBO J. 22:2472–2483.
   PubMed Web of Science ®Google Scholar
• Huang, Y., R. Gattoni, J. Stevenin, and J. A. Steitz. 2003. SR splicing factors serve as adapter proteins for TAP-dependent mRNA export. Mol. Cell 11:837–843.
   PubMed Web of Science ®Google Scholar
• Huang, Y., and J. A. Steitz. 2001. Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. Mol. Cell 7:899–905.
   PubMed Web of Science ®Google Scholar
• Huang, Y., K. M. Wimler, and G. G. Carmichael. 1999. Intronless mRNA transport elements may affect multiple steps of pre-mRNA processing. EMBO J. 18:1642–1652.
   PubMed Web of Science ®Google Scholar
• Huang, Y., T. A. Yario, and J. A. Steitz. 2004. A molecular link between SR protein dephosphorylation and mRNA export. Proc. Natl. Acad. Sci. USA 101:9666–9670.
   PubMed Web of Science ®Google Scholar
• Katahira, J., K. Strasser, A. Podtelejnikov, M. Mann, J. U. Jung, and E. Hurt. 1999. The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J. 18:2593–2609.
   PubMed Web of Science ®Google Scholar
• Kim, V. N., J. Yong, N. Kataoka, L. Abel, M. D. Diem, and G. Dreyfuss. 2001. The Y14 protein communicates to the cytoplasm the position of exon-exon junctions. EMBO J. 20:2062–2068.
   PubMed Web of Science ®Google Scholar
• Koffa, M. D., J. B. Clements, E. Izaurralde, S. Wadd, S. A. Wilson, I. W. Mattaj, and S. Kuersten. 2001. Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway. EMBO J. 20:5769–5778.
   PubMed Web of Science ®Google Scholar
• Korneeva, N. L., E. A. First, C. A. Benoit, and R. E. Rhoads. 2005. Interaction between the NH2-terminal domain of eIF4A and the central domain of eIF4G modulates RNA-stimulated ATPase activity. J. Biol. Chem. 280:1872–1881.
   PubMedGoogle Scholar
• Le Hir, H., D. Gatfield, E. Izaurralde, and M. J. Moore. 2001. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. EMBO J. 20:4987–4997.
   PubMed Web of Science ®Google Scholar
• Le Hir, H., E. Izaurralde, L. E. Maquat, and M. J. Moore. 2000. The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions. EMBO J. 19:6860–6869.
   PubMed Web of Science ®Google Scholar
• Longman, D., I. L. Johnstone, and J. F. Caceres. 2003. The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA 9:881–891.
   PubMed Web of Science ®Google Scholar
• Luo, M. L., Z. Zhou, K. Magni, C. Christoforides, J. Rappsilber, M. Mann, and R. Reed. 2001. Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature 413:644–647.
   PubMed Web of Science ®Google Scholar
• MacMorris, M., C. Brocker, and T. Blumenthal. 2003. UAP56 levels affect viability and mRNA export in Caenorhabditis elegans. RNA 9:847–857.
   PubMed Web of Science ®Google Scholar
• Masuda, S., R. Das, H. Cheng, E. Hurt, N. Dorman, and R. Reed. 2005. Recruitment of the human TREX complex to mRNA during splicing. Genes Dev. 19:1512–1517.
   PubMed Web of Science ®Google Scholar
• Masuyama, K., I. Taniguchi, N. Kataoka, and M. Ohno. 2004. RNA length defines RNA export pathway. Genes Dev. 18:2074–2085.
   PubMed Web of Science ®Google Scholar
• Nojima, T., T. Hirose, H. Kimura, and M. Hagiwara. 2007. The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export. J. Biol. Chem. 282:15645–15651.
   PubMed Web of Science ®Google Scholar
• O'Donnell, M., and J. Kuriyan. 2006. Clamp loaders and replication initiation. Curr. Opin. Struct. Biol. 16:35–41.
   PubMed Web of Science ®Google Scholar
• Ohno, M., A. Segref, S. Kuersten, and I. W. Mattaj. 2002. Identity elements used in export of mRNAs. Mol. Cell 9:659–671.
   PubMedGoogle Scholar
• Rehwinkel, J., A. Herold, K. Gari, T. Kocher, M. Rode, F. L. Ciccarelli, M. Wilm, and E. Izaurralde. 2004. Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Nat. Struct. Mol. Biol. 11:558–566.
   PubMed Web of Science ®Google Scholar
• Rodrigues, J. P., M. Rode, D. Gatfield, B. J. Blencowe, M. Carmo-Fonseca, and E. Izaurralde. 2001. REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus. Proc. Natl. Acad. Sci. USA 98:1030–1035.
   PubMed Web of Science ®Google Scholar
• Saavedra, C., B. Felber, and E. Izaurralde. 1997. The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export. Curr. Biol. 7:619–628.
   PubMed Web of Science ®Google Scholar
• Segref, A., K. Sharma, V. Doye, A. Hellwig, J. Huber, R. Luhrmann, and E. Hurt. 1997. Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores. EMBO J. 16:3256–3271.
   PubMed Web of Science ®Google Scholar
• Shen, J., L. Zhang, and R. Zhao. 2007. Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factor. J. Biol. Chem. 282:22544–22550.
   PubMed Web of Science ®Google Scholar
• Shi, H., O. Cordin, C. M. Minder, P. Linder, and R. M. Xu. 2004. Crystal structure of the human ATP-dependent splicing and export factor UAP56. Proc. Natl. Acad. Sci. USA 101:17628–17633.
   PubMedGoogle Scholar
• Strasser, K., and E. Hurt. 2001. Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Nature 413:648–652.
   PubMed Web of Science ®Google Scholar
• Strasser, K., and E. Hurt. 2000. Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J. 19:410–420.
   PubMed Web of Science ®Google Scholar
• Strasser, K., S. Masuda, P. Mason, J. Pfannstiel, M. Oppizzi, S. Rodriguez-Navarro, A. G. Rondon, A. Aguilera, K. Struhl, R. Reed, and E. Hurt. 2002. TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417:304–308.
   PubMed Web of Science ®Google Scholar
• Stutz, F., A. Bachi, T. Doerks, I. C. Braun, B. Seraphin, M. Wilm, P. Bork, and E. Izaurralde. 2000. REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA 6:638–650.
   PubMed Web of Science ®Google Scholar
• Tran, E. J., and S. R. Wente. 2006. Dynamic nuclear pore complexes: life on the edge. Cell 125:1041–1053.
   PubMed Web of Science ®Google Scholar
• Zhou, Z., M. J. Luo, K. Straesser, J. Katahira, E. Hurt, and R. Reed. 2000. The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 407:401–405.
   PubMedGoogle Scholar