Molecular and Cellular Biology, Volume 28, Issue 2 (2008)

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Molecular and Cellular Biology, Volume 28, Issue 2 (2008)

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Articles

Article
Thalidomide Induces Limb Anomalies by PTEN Stabilization, Akt Suppression, and Stimulation of Caspase-Dependent Cell Death
Jürgen Knobloch, Ingo Schmitz, Katrin Götz, Klaus Schulze-Osthoff & Ulrich Rüther
Pages: 529-538
Published online: 27 Mar 2023
AbstractforThalidomide Induces Limb Anomalies by PTEN Stabilization, Akt Suppression, and Stimulation of Caspase-Dependent Cell Death | Full Text | References | PDF (438.2 KB)
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Article
Prosurvival Effect of DHCR24/Seladin-1 in Acute and Chronic Responses to Oxidative Stress
Katrin Kuehnle, Arames Crameri, Roland E. Kälin, Paola Luciani, Susanna Benvenuti, Alessandro Peri, Francesca Ratti, Monica Rodolfo, Luka Kulic, Frank L. Heppner, Roger M. Nitsch & M. Hasan Mohajeri
Pages: 539-550
Published online: 27 Mar 2023
AbstractforProsurvival Effect of DHCR24/Seladin-1 in Acute and Chronic Responses to Oxidative Stress | Full Text | References | PDF (1.1 MB)
  • 27 Views
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Article
Activation of the SPS Amino Acid-Sensing Pathway in Saccharomyces cerevisiae Correlates with the Phosphorylation State of a Sensor Component, Ptr3
Zhengchang Liu, Janet Thornton, Mário Spírek & Ronald A. Butow
Pages: 551-563
Published online: 27 Mar 2023
AbstractforActivation of the SPS Amino Acid-Sensing Pathway in Saccharomyces cerevisiae Correlates with the Phosphorylation State of a Sensor Component, Ptr3 | Full Text | References | PDF (479.4 KB) | Supplemental
  • 33 Views
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Article
p53 Initiates Apoptosis by Transcriptionally Targeting the Antiapoptotic Protein ARC
Yu-Zhen Li, Dao-Yuan Lu, Wei-Qi Tan, Jian-Xun Wang & Pei-Feng Li
Pages: 564-574
Published online: 27 Mar 2023
Abstractforp53 Initiates Apoptosis by Transcriptionally Targeting the Antiapoptotic Protein ARC | Full Text | References | PDF (525.4 KB)
  • 14 Views
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Article
GATA-1 Modulates the Chromatin Structure and Activity of the Chicken α-Globin 3′ Enhancer
Martín Escamilla-Del-Arenal & Félix Recillas-Targa
Pages: 575-586
Published online: 27 Mar 2023
AbstractforGATA-1 Modulates the Chromatin Structure and Activity of the Chicken α-Globin 3′ Enhancer | Full Text | References | PDF (669.1 KB) | Supplemental
  • 9 Views
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Article
Signal Strength Dictates Phosphoinositide 3-Kinase Contribution to Ras/Extracellular Signal-Regulated Kinase 1 and 2 Activation via Differential Gab1/Shp2 Recruitment: Consequences for Resistance to Epidermal Growth Factor Receptor Inhibition
Carla Sampaio, Marie Dance, Alexandra Montagner, Thomas Edouard, Nicole Malet, Bertrand Perret, Armelle Yart, Jean-Pierre Salles & Patrick Raynal
Pages: 587-600
Published online: 27 Mar 2023
AbstractforSignal Strength Dictates Phosphoinositide 3-Kinase Contribution to Ras/Extracellular Signal-Regulated Kinase 1 and 2 Activation via Differential Gab1/Shp2 Recruitment: Consequences for Resistance to Epidermal Growth Factor Receptor Inhibition | Full Text | References | PDF (690.5 KB) | Supplemental
  • 15 Views
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Article
ATP-Dependent Recruitment of Export Factor Aly/REF onto Intronless mRNAs by RNA Helicase UAP56
Ichiro Taniguchi & Mutsuhito Ohno
Pages: 601-608
Published online: 27 Mar 2023
AbstractforATP-Dependent Recruitment of Export Factor Aly/REF onto Intronless mRNAs by RNA Helicase UAP56 | Full Text | References | PDF (463.1 KB)
  • 99 Views
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Article
Wdr82 Is a C-Terminal Domain-Binding Protein That Recruits the Setd1A Histone H3-Lys4 Methyltransferase Complex to Transcription Start Sites of Transcribed Human Genes
Jeong-Heon Lee & David G. Skalnik
Pages: 609-618
Published online: 27 Mar 2023
AbstractforWdr82 Is a C-Terminal Domain-Binding Protein That Recruits the Setd1A Histone H3-Lys4 Methyltransferase Complex to Transcription Start Sites of Transcribed Human Genes | Full Text | References | PDF (463.6 KB)
  • 245 Views
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Article
Deletion of Rnt1p Alters the Proportion of Open versus Closed rRNA Gene Repeats in Yeast
Mathieu Catala, Maxime Tremblay, Éric Samson, Antonio Conconi & Sherif Abou Elela
Pages: 619-629
Published online: 27 Mar 2023
AbstractforDeletion of Rnt1p Alters the Proportion of Open versus Closed rRNA Gene Repeats in Yeast | Full Text | References | PDF (435.8 KB)
  • 19 Views
  • 18 CrossRef citations
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Article
The SH3 Domain of Lck Modulates T-Cell Receptor-Dependent Activation of Extracellular Signal-Regulated Kinase through Activation of Raf-1
Manqing Li, Su Sien Ong, Bartek Rajwa, Vivian T. Thieu, Robert L. Geahlen & Marietta L. Harrison
Pages: 630-641
Published online: 27 Mar 2023
AbstractforThe SH3 Domain of Lck Modulates T-Cell Receptor-Dependent Activation of Extracellular Signal-Regulated Kinase through Activation of Raf-1 | Full Text | References | PDF (741.3 KB)
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Article
c-Src-Mediated Epithelial Cell Migration and Invasion Regulated by PDZ Binding Site
Martin Baumgartner, Gerald Radziwill, Mihaela Lorger, Andreas Weiss & Karin Moelling
Pages: 642-655
Published online: 27 Mar 2023
Abstractforc-Src-Mediated Epithelial Cell Migration and Invasion Regulated by PDZ Binding Site | Full Text | References | PDF (1.2 MB) | Supplemental
  • 18 Views
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Article
Global Role for Polyadenylation-Assisted Nuclear RNA Degradation in Posttranscriptional Gene Silencing
Shao-Win Wang, Abigail L. Stevenson, Stephen E. Kearsey, Stephen Watt & Jürg Bähler
Pages: 656-665
Published online: 27 Mar 2023
AbstractforGlobal Role for Polyadenylation-Assisted Nuclear RNA Degradation in Posttranscriptional Gene Silencing | Full Text | References | PDF (684.1 KB)
  • 18 Views
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Article
GRP78 and Cripto Form a Complex at the Cell Surface and Collaborate To Inhibit Transforming Growth Factor β Signaling and Enhance Cell Growth
Gidi Shani, Wolfgang H. Fischer, Nicholas J. Justice, Jonathan A. Kelber, Wylie Vale & Peter C. Gray
Pages: 666-677
Published online: 27 Mar 2023
AbstractforGRP78 and Cripto Form a Complex at the Cell Surface and Collaborate To Inhibit Transforming Growth Factor β Signaling and Enhance Cell Growth | Full Text | References | PDF (726.3 KB)
  • 45 Views
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Article
PTB/hnRNP I Is Required for RNP Remodeling during RNA Localization in Xenopus Oocytes
Raymond A. Lewis, James A. Gagnon & Kimberly L. Mowry
Pages: 678-686
Published online: 27 Mar 2023
AbstractforPTB/hnRNP I Is Required for RNP Remodeling during RNA Localization in Xenopus Oocytes | Full Text | References | PDF (390.1 KB)
  • 6 Views
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Article
Parvin-β Inhibits Breast Cancer Tumorigenicity and Promotes CDK9-Mediated Peroxisome Proliferator-Activated Receptor Gamma 1 Phosphorylation
Cameron N. Johnstone, Perry S. Mongroo, A. Sophie Rich, Michael Schupp, Mark J. Bowser, Andrew S. deLemos, John W. Tobias, Yingqiu Liu, Gregory E. Hannigan & Anil K. Rustgi
Pages: 687-704
Published online: 27 Mar 2023
AbstractforParvin-β Inhibits Breast Cancer Tumorigenicity and Promotes CDK9-Mediated Peroxisome Proliferator-Activated Receptor Gamma 1 Phosphorylation | Full Text | References | PDF (1.4 MB) | Supplemental
  • 42 Views
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Article
ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation
Panagiota Karagianni, Larbi Amazit, Jun Qin & Jiemin Wong
Pages: 705-717
Published online: 27 Mar 2023
AbstractforICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation | Full Text | References | PDF (1.1 MB)
  • 28 Views
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Article
Loss of the SdhB, but Not the SdhA, Subunit of Complex II Triggers Reactive Oxygen Species-Dependent Hypoxia-Inducible Factor Activation and Tumorigenesis
Robert D. Guzy, Bhumika Sharma, Eric Bell, Navdeep S. Chandel & Paul T. Schumacker
Pages: 718-731
Published online: 27 Mar 2023
AbstractforLoss of the SdhB, but Not the SdhA, Subunit of Complex II Triggers Reactive Oxygen Species-Dependent Hypoxia-Inducible Factor Activation and Tumorigenesis | Full Text | References | PDF (735.4 KB)
  • 155 Views
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Article
RPEL Motifs Link the Serum Response Factor Cofactor MAL but Not Myocardin to Rho Signaling via Actin Binding
Sebastian Guettler, Maria K. Vartiainen, Francesc Miralles, Banafshe Larijani & Richard Treisman
Pages: 732-742
Published online: 27 Mar 2023
AbstractforRPEL Motifs Link the Serum Response Factor Cofactor MAL but Not Myocardin to Rho Signaling via Actin Binding | Full Text | References | PDF (3 MB) | Supplemental
  • 88 Views
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Article
Disruption of the Fbxw8 Gene Results in Pre- and Postnatal Growth Retardation in Mice
Takeya Tsutsumi, Hiroshi Kuwabara, Takehiro Arai, Yonghong Xiao & James A. DeCaprio
Pages: 743-751
Published online: 27 Mar 2023
AbstractforDisruption of the Fbxw8 Gene Results in Pre- and Postnatal Growth Retardation in Mice | Full Text | References | PDF (450.9 KB) | Supplemental
  • 46 Views
  • 39 CrossRef citations
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Article
DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B
Stela S. Palii, Beth O. Van Emburgh, Umesh T. Sankpal, Kevin D. Brown & Keith D. Robertson
Pages: 752-771
Published online: 27 Mar 2023
AbstractforDNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B | Full Text | References | PDF (1 MB)
  • 181 Views
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Article
Double-Stranded RNA-Binding Protein Regulates Vascular Endothelial Growth Factor mRNA Stability, Translation, and Breast Cancer Angiogenesis
Frank Vumbaca, Kathryn N. Phoenix, Daniel Rodriguez-Pinto, David K. Han & Kevin P. Claffey
Pages: 772-783
Published online: 27 Mar 2023
AbstractforDouble-Stranded RNA-Binding Protein Regulates Vascular Endothelial Growth Factor mRNA Stability, Translation, and Breast Cancer Angiogenesis | Full Text | References | PDF (477.6 KB)
  • 29 Views
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Article
Expression Levels of Estrogen Receptor β Are Modulated by Components of the Molecular Clock
Wen Cai, Juliette Rambaud, Michèle Teboul, Ingrid Masse, Gerard Benoit, Jan-Åke Gustafsson, Franck Delaunay, Vincent Laudet & Ingemar Pongratz
Pages: 784-793
Published online: 27 Mar 2023
AbstractforExpression Levels of Estrogen Receptor β Are Modulated by Components of the Molecular Clock | Full Text | References | PDF (499.1 KB)
  • 84 Views
  • 57 CrossRef citations
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Article
Endothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling
Li Lei, Dinggang Liu, Yan Huang, Ion Jovin, Shaw-Yung Shai, Themis Kyriakides, Robert S. Ross & Frank J. Giordano
Pages: 794-802
Published online: 27 Mar 2023
AbstractforEndothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling | Full Text | References | PDF (899.1 KB)
  • 53 Views
  • 75 CrossRef citations
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Article
Proline-Rich Transcript in Brain Protein Induces Stress Granule Formation
Jung-Eun Kim, Incheol Ryu, Woo Jae Kim, Ok-Kyu Song, Jeongeun Ryu, Mi Yi Kwon, Joon Hyun Kim & Sung Key Jang
Pages: 803-813
Published online: 27 Mar 2023
AbstractforProline-Rich Transcript in Brain Protein Induces Stress Granule Formation | Full Text | References | PDF (1.3 MB) | Supplemental
  • 36 Views
  • 24 CrossRef citations
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Article
Functional Localization of Two Poly(ADP-Ribose)-Degrading Enzymes to the Mitochondrial Matrix
Marc Niere, Stefan Kernstock, Friedrich Koch-Nolte & Mathias Ziegler
Pages: 814-824
Published online: 27 Mar 2023
AbstractforFunctional Localization of Two Poly(ADP-Ribose)-Degrading Enzymes to the Mitochondrial Matrix | Full Text | References | PDF (1.1 MB)
  • 60 Views
  • 79 CrossRef citations
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Article
Defining the Roles of β-Catenin and Plakoglobin in LEF/T-Cell Factor-Dependent Transcription Using β-Catenin/Plakoglobin-Null F9 Cells
Masayuki Shimizu, Yoshitaka Fukunaga, Junichi Ikenouchi & Akira Nagafuchi
Pages: 825-835
Published online: 27 Mar 2023
AbstractforDefining the Roles of β-Catenin and Plakoglobin in LEF/T-Cell Factor-Dependent Transcription Using β-Catenin/Plakoglobin-Null F9 Cells | Full Text | References | PDF (633.9 KB)
  • 11 Views
  • 30 CrossRef citations
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Article
A Mouse Gene That Coordinates Epigenetic Controls and Transcriptional Interference To Achieve Tissue-Specific Expression
Alexandra C. Racanelli, Fiona B. Turner, Lin-Ying Xie, Shirley M. Taylor & Richard G. Moran
Pages: 836-848
Published online: 27 Mar 2023
AbstractforA Mouse Gene That Coordinates Epigenetic Controls and Transcriptional Interference To Achieve Tissue-Specific Expression | Full Text | References | PDF (1.3 MB) | Supplemental
  • 16 Views
  • 8 CrossRef citations
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Article
Functional Coupling of Last-Intron Splicing and 3′-End Processing to Transcription In Vitro: the Poly(A) Signal Couples to Splicing before Committing to Cleavage
Frank Rigo & Harold G. Martinson
Pages: 849-862
Published online: 27 Mar 2023
AbstractforFunctional Coupling of Last-Intron Splicing and 3′-End Processing to Transcription In Vitro: the Poly(A) Signal Couples to Splicing before Committing to Cleavage | Full Text | References | PDF (638.8 KB) | Supplemental
  • 25 Views
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Article
Naturally Extended CT · AG Repeats Increase H-DNA Structures and Promoter Activity in the Smooth Muscle Myosin Light Chain Kinase Gene
Yoo-Jeong Han & Primal de Lanerolle
Pages: 863-872
Published online: 27 Mar 2023
AbstractforNaturally Extended CT · AG Repeats Increase H-DNA Structures and Promoter Activity in the Smooth Muscle Myosin Light Chain Kinase Gene | Full Text | References | PDF (335.1 KB)
  • 9 Views
  • 19 CrossRef citations
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Article
Protein Phosphatase 2A Subunit PR70 Interacts with pRb and Mediates Its Dephosphorylation
Alessandra Magenta, Pasquale Fasanaro, Sveva Romani, Valeria Di Stefano, Maurizio C. Capogrossi & Fabio Martelli
Pages: 873-882
Published online: 27 Mar 2023
AbstractforProtein Phosphatase 2A Subunit PR70 Interacts with pRb and Mediates Its Dephosphorylation | Full Text | References | PDF (407.7 KB)
  • 19 Views
  • 45 CrossRef citations
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Article
Caffeine Regulates Alternative Splicing in a Subset of Cancer-Associated Genes: a Role for SC35
Jia Shi, Zhen Hu, Kirk Pabon & Kathleen W. Scotto
Pages: 883-895
Published online: 27 Mar 2023
AbstractforCaffeine Regulates Alternative Splicing in a Subset of Cancer-Associated Genes: a Role for SC35 | Full Text | References | PDF (892.9 KB)
  • 46 Views
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