33
Views
40
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Down-Regulation of RpS21, a Putative Translation Initiation Factor Interacting with P40, Produces Viable Minute Imagos and Larval Lethality with Overgrown Hematopoietic Organs and Imaginal Discs

, , , , , & show all
Pages 2308-2321 | Received 27 Aug 1998, Accepted 07 Dec 1998, Published online: 27 Mar 2023

REFERENCES

  • Andersson, S., S. Saebøe-Larssen, A. Lambertsson, J. Merriam, and J. Jacobs-Lorena 1994. A Drosophila third chromosome Minute locus encodes a ribosomal protein. Genetics 137:513–520.
  • Ashburner, M. 1989. Drosophila: a laboratory handbook. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Auth, D., and J. Brawerman 1992. A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery. Proc. Natl. Acad. Sci. USA 89:4368–4372.
  • Barnard, G. F., R. J. Staniunas, M. Mori, M. Puder, M. J. Jessup, G. D. Steele, and J. Chen 1993. Gastric and hepatocellular carcinomas do not overexpress the same ribosomal protein messenger RNAs as colonic carcinoma. Cancer Res. 53:4048–4052.
  • Barnard, G. F., R. J. Staniunas, M. Puder, G. D. Steele, and J. Chen 1994. Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. Biochim. Biophys. Acta 1218:425–428.
  • Bartel, P., C. T. Chien, R. Sternglanz, and J. Fields 1993. Elimination of false positives that arise in using the two-hybrid system. BioTechniques 14:920–924.
  • Belyaeva, E. S., M. G. Aizenzon, V. F. Semeshin, I. I. Kiss, K. Koczka, E. M. Baritcheva, T. V. Gorelova, and J. Zhimulev 1980. Cytogenetic analysis of the 2B3-4-2B11 region of the X-chromosome of Drosophila melanogaster. I. Cytology of the region and mutant complementation groups. Chromosoma 81:281–306.
  • Bhat, K. S., and J. Morrison 1993. Primary structure of human ribosomal protein S21. Nucleic Acids Res. 21:2939.
  • Bommer, U. A., G. Lutsch, J. Stahl, and J. Bielka 1991. Eukaryotic initiation factors eIF-2 and eIF-3: interactions, structure and localization in ribosomal initiation complexes. Biochemie 73:1007–1019.
  • Bray, D. F., J. Bagu, and J. Koegler 1993. Comparison of hexamethyldisilazane (HMDS), Peldri II, and critical-point drying methods for scanning electron microscopy of biological specimens. Microsc. Res. Tech. 15:489–495.
  • Cavener, D. R. 1987. Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res. 15:1353–1361.
  • Cervera, M., G. Dreyfuss, and J. Penman 1981. Messenger RNA is translated when associated with the cytoskeletal framework from normal and VSV-infected HeLa cells. Cell 23:113–120.
  • Chan, Y.-L., J.-J. Diaz, L. Deneroy, J.-J. Madjar, and J. Wool 1996. The primary structure of rat ribosomal protein L10: relationship to a Jun-binding protein and to a putative Wilms’ tumor suppressor. Biochem. Biophys. Res. Commun. 225:952–956.
  • Chiao, P. J., D. M. Shin, P. G. Sacks, W. K. Hong, and J. Tainsky 1992. Elevated expression of the ribosomal protein S2 gene in human tumors. Mol. Carcinog. 5:219–231.
  • Chester, K. A., L. Robson, R. H. J. Begent, I. C. Talbot, J. H. Pringle, L. Primrose, A. J. S. Macpherson, G. Boxer, P. Southall, P., and J. Malcolm 1989. Identification of a human ribosomal protein mRNA with increased expression in colorectal tumours. Biochim. Biophys. Acta 1009:297–300.
  • Cramton, S. E., and J. Laski 1994. string of pearls encodes Drosophila ribosomal protein S2, has Minute-like characteristics, and is required during oogenesis. Genetics 137:1039–1048.
  • Davis, S. C., A. Tzagoloff, and J. Ellis 1992. Characterization of a yeast mitochondrial ribosomal protein structurally related to the mammalian 67-kDa high-affinity laminin receptor. J. Biol. Chem. 267:5508–5514.
  • De Frutos, R., K. Kimura, and J. Peterson 1990. In situ hybridization of Drosophila polytene chromosomes with digoxigenin-dUTP labelled probes. Methods Mol. Cell. Biol. 2:32–36.
  • Deutsch, W. A., A. Yacoub, P. Jaruga, T. H. Zastawny, and J. Dizdaroglu 1997. Characterization and mechanism of action of ribosomal protein S3 DNA glycosylase activity for the removal of oxidatively damaged DNA bases. J. Biol. Chem. 272:32857–32860.
  • Dick, F. A., S. Karamamou, and J. Trumpower 1997. QSR1, an essential yeast gene with a genetic relationship to a subunit of the mitochondrial cytochrome bc1 complex codes for a 60S ribosomal subunit protein. J. Biol. Chem. 272:13373–13379.
  • Dowdy, S. F., K. M. Lai, B. E. Weissman, Y. Matsui, B. L. Hogan, and J. Stanbridge 1991. The isolation and characterization of a novel cDNA demonstrating an altered mRNA level in nontumorigenic Wilms’ microcell hybrid cell. Nucleic Acids Res. 19:5763–5769.
  • Eisinger, D. F. P., F. A. Dick, and J. Trumpower 1997. Qsr1p, a 60S ribosomal subunit protein is required for joining of 40S and 60S subunits. Mol. Cell. Biol. 17:5136–5145.
  • Eisinger, D. F. P., H. P. Jiang, and J. Serrero 1993. A novel mouse gene highly conserved throughout evolution: regulation in adipocyte differentiation and in tumorigenic lines. Biochem. Biophys. Res. Commun. 196:1227–1232.
  • Ferrari, S., and J. Thomas 1994. S6 phosphorylation and the p70s6k/p85s6k. CRC Crit. Rev. Biochem. Mol. Biol. 29:385–413.
  • Fisher, E. M. C., P. Beer-Romero, L. G. Brown, A. Ridley, J. A. McNell, J. B. Lawrence, H. F. Willard, F. R. Bieber, and J. Page 1990. Homologous ribosomal protein genes on the X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell 63:1205–1218.
  • Gateff, E., and J. Mechler 1989. Tumour suppressor genes of Drosophila melanogaster. Crit. Rev. Oncog. 1:221–245.
  • Grabowski, D. T., R. O. Pieper, B. W. Futscher, W. A. Deutsch, L. C. Erikson, and J. Kelley 1992. Expression of ribosomal phosphoprotein P0 is induced by antitumor agents and increased in Mer-human tumor cell lines. Carcinogenesis 13:259–263.
  • Harlow, E., D. Lane 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Hart, K., T. Klein, and J. Wilcox 1993. A Minute encoding a ribosomal protein enhances wing morphogenesis mutants. Mech. Dev. 43:101–110.
  • Henry, J. L., D. L. Coggin, and J. King 1993. High-level expression of the ribosomal protein L19 in human breast tumors that overexpress erbB-2. Cancer Res. 53:1403–1408.
  • Howe, J. G., and J. Hershey 1984. Translation initiation factor and ribosome association with the cytoskeletal framework fraction from HeLa cells. Cell 37:85–93.
  • Itoh, T., E. Otaka, and J. Matsui 1985. Primary structures of ribosomal YS25 from Saccharomyces cerevisiae and its counterparts from Schizosaccharomyces pombe and rat liver. Biochemistry 24:7418–7423.
  • Jefferies, H. B. J., C. Reinhard, S. C. Kozma, and J. Thomas 1994. Rapamycin selectively represses translation of the “polypyrimine tract” mRNA family. Proc. Natl. Acad. Sci. USA 91:4441–4445.
  • Kaneko, K., H. Kobayashi, O. Onodera, T. Miyatake, and J. Tsuji 1992. Genomic organization of a cDNA (QM) demonstrating an altered mRNA level in nontumorigenic Wilms’ microcell hybrid cells and its localization to Xq28. Hum. Mol. Genet. 1:529–533.
  • Keppel, E., and J. Schaller 1991. A 33-kDa protein with sequence homology to the “laminin binding protein” is associated with the cytoskeleton in hydra and in mammalian cells. J. Cell Sci. 100:789–797.
  • Kim, J., L. S. Chubatsu, A. Admon, J. Stahl, R. Fellous, and J. Linn 1995. Implication of mammalian ribosomal protein S3 in the processing of DNA damage. J. Biol. Chem. 270:13620–13629.
  • Kitayama, H., Y. Sugimoto, T. Matsuzaki, Y. Ikawa, and J. Noda 1989. A ras-related gene with transformation suppressor activity. Cell 56:77–84.
  • Koller, H. T., T. Klade, A. Ellinger, and J. Breitenbach 1996. The yeast growth control gene GRC5 is highly homologous to the mammalian putative tumor suppressor gene QM. Yeast 12:53–65.
  • Kondoh, N., M. Noda, R. J. Fisher, C. W. Schweinfest, T. S. Papas, A. Kondoh, K. P. Samuel, and J. Oikawa 1996. The S29 ribosomal protein increases tumor suppressor activity of Krev-1 gene on v-K ras-transformed NIH3T3 cells. Biochim. Biophys. Acta 1313:41–46.
  • Kondoh, N., C. W. Schweinfest, K. W. Henderson, and J. Papas 1992. Differential expression of S19 ribosomal protein, laminin-binding protein, and human lymphocyte antigen class I messenger RNAs associated with colon carcinoma progression and differentiation. Cancer Res. 52:791–796.
  • Kongsuwan, K., Y. Qiang, A. Vincent, M. C. Frisardi, and J. Rosbash 1985. A Drosophila Minute gene encodes a ribosomal protein. Nature 317:555–558.
  • Lindsley, D. L., G. G. Zimm 1992. The genome of Drosophila melanogaster. Academic Press, Inc., San Diego, Calif.
  • Loftus, T. M., Y. E. Nguyen, and J. Stanbridge 1997. The QM protein associates with ribosomes in the rough endoplasmic reticulum. Biochemistry 36:8224–8230.
  • Lutsch, G., F. Noll, H. Theise, G. Enzmann, and J. Bielka 1979. Localization of proteins S1, S2, S16 and S23 on the surface of small subunits of rat liver ribosomes by immune electron microscopy. Mol. Gen. Genet. 176:281–291.
  • Marion, M.-J., and J. Marion 1988. Ribosomal proteins S2, S6, S10, S14, S15, and S25 are localized on the surface of mammalian 40S subunits and stabilized their conformation. FEBS Lett. 232:281–285.
  • McKim, K. S., J. B. Dahmus, and J. Hawley 1996. Cloning of the Drosophila melanogaster meiotic recombination gene mei-218: a genetic and molecular analysis of interval 15E. Genetics 144:215–228.
  • Mechler, B. M. 1994. Genes in control of cell proliferation and tumorigenesis in Drosophila, p. 183–198. In S. Gordon (ed.), The legacy of cell fusion. Oxford University Press, Oxford, England.
  • Melnick, M. B., E. Noll, and J. Perrimon 1993. The Drosophila stubarista phenotype is associated with a dosage effect of the putative ribosome-associated protein D-p40 on spineless. Genetics 135:553–564.
  • Meyuhas, O., D. Avni, S. Shama 1996. Translational control of ribosomal protein mRNAs in eukaryotes, p. 363–388. In J. W. B. Hershey, M. Mathews, S. Sonenberg (ed.), Translational control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Mitchelson, A., M. Simonelig, C. J. Williams, and J. O’Hare 1993. Homology with Saccharomyces cerevisiae RNA14 suggests that phenotypic suppression in Drosophila melanogaster by suppressor of forked occurs at the level of RNA stability. Genes Dev. 7:241–249.
  • Nishi, R., H. Hashimoto, H. Uchimiya, and J. Kato 1993. The primary structure of two proteins from the small ribosomal subunit of rice. Biochim. Biophys. Acta 1216:113–114.
  • Nygärd, O., and J. Nilsson 1990. Translational dynamics. Interactions between the translation factors, tRNA and ribosomes during eukaryotic protein synthesis. Eur. J. Biochem. 191:1–17.
  • O’Hare, K., and J. Rubin 1983. Structure of P-transposable elements and their sites of insertion and excision in the Drosophila melanogaster genome. Cell 34:25–35.
  • Oliver, C. P. 1935. New mutants report. Drosophila Infor. Service 4:15.
  • Palen, E., and J. Traugh 1987. Phosphorylation of ribosomal protein S6 by cAMP-dependent protein kinase and mitogen-stimulated S6 kinase differently alters translation of globin mRNA. J. Biol. Chem. 262:3528–3523.
  • Pirrotta, V. 1988. Vectors for P-element transformation in Drosophila, p. 437–456. In R. L. Rodriguez, D. T. Renhardt (ed.), Vectors: a survey of molecular cloning vectors and their uses. Butterworths, London, England.
  • Pogue-Geile, K., J. R. Geiser, M. Shu, C. Miller, I. G. Wool, A. I. Meisler, and J. Pipas 1991. Ribosomal protein genes are overexpressed in colorectal cancer: isolation of a cDNA clone encoding the human S3 ribosomal protein. Mol. Cell. Biol. 11:3842–3849.
  • Ritossa, F. 1976. The bobbed locus The genetics and biology of Drosophila In M. Ashburner, E. Novitski (ed.), 1B:801–846 Academic Press, Inc., London, England.
  • Rizki, T. M. 1978. The circulatory system and associated cells and tissues The genetics and biology of Drosophila In M. Ashburner, T. R. F. Wright (ed.), 2B:397–452 Academic Press, Inc., London, England.
  • Saebøe-Larssen, S., and J. Lambertsson 1996. A novel Drosophila Minute locus encodes ribosomal protein S13. Genetics 143:877–885.
  • Saebøe-Larssen, S., B. Urbanczyk-Mohebi, and J. Lambertsson 1997. The Drosophila ribosomal protein L14-encoding gene, identified by a novel Minute mutation in a dense cluster of previously undescribed genes in cytogenetic region 66D. Mol. Gen. Genet. 225:141–151.
  • Saebøe-Larssen, S., M. Lyamouri, J. Merriam, M. P. Oksvold, and J. Lambertsson 1998. Ribosomal protein insufficiency and the Minute syndrome in Drosophila: a dose-response relationship. Genetics 148:1215–1224.
  • Sambrook, J., E. F. Fritsch, T. Maniatis 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Sandigursky, M., A. Yacoub, M. R. Kelley, W. A. Deutsch, and J. Franklin 1997. The Drosophila ribosomal protein S3 contains a DNA deoxyribophosphodiesterase (dRpase) activity. J. Biol. Chem. 272:17480–17484.
  • Schmidt, A., M. Hollmann, and J. Schäfer 1996. A newly identified Minute locus, M(2)32D, encodes the ribosomal protein L9 in Drosophila melanogaster. Mol. Gen. Genet. 251:381–387.
  • Sharp, M. G. F., S. M. Adams, P. Elvin, R. A. Walker, W. J. Brammar, and J. Varley 1990. A sequence previously identified as metastasis-related encodes an acidic ribosomal phosphoprotein, P2. Br. J. Cancer 61:83–88.
  • Shimuzu, M., and J. Craven 1976. Chemical inactivation of Escherichia coli 30-S ribosomes by iodination. Eur. J. Biochem. 61:307–315.
  • Shrestha, R., and J. Gateff 1982. Ultrastructure and cytochemistry of the cell types in the larval hematopoietic organs and hemolymph of Drosophila melanogaster. Dev. Growth Differ. 24:65–82.
  • Stewart, M. J., and J. Denell 1993. Mutations in the Drosophila gene encoding ribosomal protein S6 cause tissue overgrowth. Mol. Cell. Biol. 13:2524–2535.
  • Suzuki, K., and J. Otoka 1988. Cloning and nucleotide sequence of the gene encoding yeast ribosomal protein S25. Nucleic Acids Res. 16:6223.
  • Szabad, J., and J. Bryant 1982. The mode of action of discless mutations in Drosophila melanogaster. Dev. Biol. 93:240–256.
  • Terada, N., H. R. Patel, K. Takase, K. Kohno, A. C. Nairn, and J. Gelfand 1994. Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proc. Natl. Acad. Sci. USA 91:11477–11481.
  • Thomas, G., R. Sweeney, C. Chang, and J. Noller 1975. Identification of proteins functionally altered by chemical modification of the transfer RNA and polyuridilic acid binding sites of 30S ribosomal subunits. J. Mol. Biol. 95:91–102.
  • Tolan, D. R., and J. Traut 1981. Protein topography of the 40S ribosomal subunit from rabbit reticulocytes shown by cross-linking with 2-iminothiolane. J. Biol. Chem. 256:10129–10136.
  • Török, I., K. Hartenstein, A. Kalmes, R. Schmitt, D. Strand, and J. Mechler 1993. The l(2)gl homologue of Drosophila pseudoobscura suppresses tumorigenicity in transgenic Drosophila melanogaster. Oncogene 8:1537–1549.
  • Török, I., D. Strand, R. Schmitt, G. Tick, T. Török, I. Kiss, and J. Mechler 1995. The overgrown hematopoietic organs-31 tumor suppressor gene of Drosophila encodes an importin-like protein accumulating in the nucleus at the onset of mitosis. J. Cell Biol. 129:1473–1489.
  • Török, T., G. Tick, M. Alvarado, and J. Kiss 1993. P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes. Genetics 135:71–80.
  • Tschudi, C., V. Pirrotta, and J. Junakovic 1982. Rearrangements of the 5S RNA gene cluster of Drosophila melanogaster associated with insertion of a B104 element. EMBO J. 1:977–985.
  • Tron, T., M. Yang, F. A. Dick, M. E. Schmitt, and J. Trumpower 1995. QSR1, an essential yeast gene with a genetic relationship to a subunit of the mitochondrial cytochrome bc1 complex is homologous to a gene implicated in eukaryotic cell differentiation. J. Biol. Chem. 270:9961–9970.
  • Watson, K. L., T. K. Johnson, and J. Denell 1991. Lethal(1)aberrant immune response mutations leading to melanotic tumor formation in Drosophila melanogaster. Dev. Genet. 12:173–187.
  • Watson, K. L., K. D. Konrad, D. F. Woods, and J. Bryant 1992. Drosophila homolog of the human S6 ribosomal protein is required for tumor suppression in the hematopoietic system. Proc. Natl. Acad. Sci. USA 89:11302–11306.
  • Wieschaus, E. 1980. A combined genetic and mosaic approach to the study of oogenesis in Drosophila Development and neurobiology of Drosophila. Basic Life Sciences In O. Siddiqui, P. Babu, L. M. Hall, J. C. Hall (ed.), 16:85–94 Plenum, Inc., New York, N.Y.
  • Wilson, D. M., W. A. Deutsch, and J. Kelley 1994. Drosophila ribosomal protein S3 contains an activity that cleaves DNA at apurinic/apyrimidic sites. J. Biol. Chem. 269:25359–25364.
  • Wong, J. M., K.-I. Mafune, H. Yow, E. N. Rivers, T. S. Ravikumar, G. D. Steele, and J. Chen 1993. Ubiquitin-ribosomal protein S27a gene overexpressed in human colorectal carcinoma is an early growth response gene. Cancer Res. 53:1916–1920.
  • Yacoub, A., L. Augeri, M. R. Kelley, P. W. Doetsch, and J. Deutsch 1996. A Drosophila ribosomal protein contains 8-oxoguanine and abasic site DNA repair activities. EMBO J. 15:2306–2312.
  • Yacoub, A., M. R. Kelley, and J. Deutsch 1996. Drosophila ribosomal protein P0 contains apurinic/apyrimidinic endonuclease activity. Nucleic Acids Res. 24:4298–4303.
  • Yow, H. K., J. M. Wong, H. S. Chen, C. G. Lee, S. Davis, G. D. Steele, and J. Chen 1988. Increased mRNA expression of a laminin-binding protein in human carcinoma: complete sequence of a full-length cDNA encoding the protein. Proc. Natl. Acad. Sci. USA 85:6394–6398.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.