A Human Protein with Sequence Similarity to Drosophila Mastermind Coordinates the Nuclear Form of Notch and a CSL Protein To Build a Transcriptional Activator Complex on Target Promoters

REFERENCES

• Artavanis-Tsakonas, S., K. Matsuno, and M. E. Fortini. 1995. Notch signaling. Science 268:225–232.
   PubMed Web of Science ®Google Scholar
• Artavanis-Tsakonas, S., M. D. Rand, and R. J. Lake. 1999. Notch signaling: cell fate control and signal integration in development. Science 284:770–776.
   PubMed Web of Science ®Google Scholar
• Bettler, D., S. Pearson, and B. Yedvobnick. 1996. The nuclear protein encoded by the Drosophila neurogenic gene mastermind is widely expressed and associates with specific chromosomal regions. Genetics 143:859–875.
   PubMedGoogle Scholar
• Capobianco, A. J., P. Zagouras, C. M. Blaumueller, S. Artavanis-Tsakonas, and J. M. Bishop. 1997. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol. Cell. Biol. 17:6265–6273.
   PubMed Web of Science ®Google Scholar
• Eastman, D. S., R. Slee, E. Skoufos, L. Bangalore, S. Bray, and C. Delidakis. 1997. Synergy between Suppressor of Hairless and Notch in regulation of Enhancer of split mγ and mδ expression. Mol. Cell. Biol. 17:5620–5628.
   PubMedGoogle Scholar
• Fortini, M. E., and S. Artavanis-Tsakonas. 1994. The suppressor of hairless protein participates in notch receptor signaling. Cell 79:273–282.
   PubMed Web of Science ®Google Scholar
• Furukawa, T., S. Maruyama, M. Kawaichi, and T. Honjo. 1992. The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development. Cell 69:1191–1197.
   PubMed Web of Science ®Google Scholar
• Helms, W., H. Lee, M. Ammerman, A. L. Parks, M. A. Muskavitch, and B. Yedvobnick. 1999. Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function. Dev. Biol. 215:358–374.
   PubMedGoogle Scholar
• Hsieh, J. J.-D., T. Henkel, P. Salmon, E. Robey, M. G. Peterson, and S. D. Hayward. 1996. Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16:952–995.
   PubMedGoogle Scholar
• Hsieh, J. J.-D., S. Zhou, L. Chen, D. B. Young, and S. D. Hayward. 1999. CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc. Natl. Acad. Sci. USA 96:23–28.
   PubMed Web of Science ®Google Scholar
• Huppert, S. S., A. Le, E. H. Schroeter, J. S. Mumm, M. T. Saxena, L. A. Milner, and R. Kopan. 2000. Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature 405:966–970.
   PubMedGoogle Scholar
• Jarriault, S., C. Brou, F. Logeat, E. H. Schroeter, R. Kopan, and A. Israel. 1995. Signalling downstream of activated mammalian Notch. Nature 377:355–358.
   PubMed Web of Science ®Google Scholar
• Kao, H. Y., P. Ordentlich, N. Koyano-Nakagawa, Z. Tang, M. Downes, C. R. Kintner, R. M. Evans, and T. Kadesch. 1998. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev. 12:2269–2277.
   PubMed Web of Science ®Google Scholar
• Kurooka, H., and T. Honjo. 2000. Functional interaction between the mouse Notch1 intracellular region and histone acetyltransferases PCAF and GCN5. J. Biol. Chem. 275:17211–17220.
   PubMed Web of Science ®Google Scholar
• Lecourtois, M., and F. Schweisguth. 1998. Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos. Curr. Biol. 8:771–774.
   PubMed Web of Science ®Google Scholar
• Lehman, R. F., W. Jimenez, U. Dietrich, and J. A. Campos-Ortega. 1983. On the phenotype and development of mutants of early neurogenesis in D. melanogaster. Wilhelm Roux's Arch. Dev. Biol. 192:62–74.
   PubMedGoogle Scholar
• Matsunami, N., Y. Hamaguchi, Y. Yamamoto, K. Kuze, K. Kangawa, H. Matsuo, M. Kawaichi, and T. Honjo. 1989. A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif. Nature 342:934–937.
   PubMedGoogle Scholar
• Mizushima, S., and S. Nagata. 1990. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18:5322
   PubMed Web of Science ®Google Scholar
• Nagase, T., N. Seki, K. Ishikawa, A. Tanaka, and N. Nomura. 1996. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161–KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 3:17–24.
   PubMedGoogle Scholar
• Newfeld, S. J., D. A. Smoller, and B. Yedvobnick. 1991. Interspecific comparison of the unusually repetitive Drosophila locus mastermind. J. Mol. Evol. 32:415–420.
   PubMedGoogle Scholar
• Nishimura, M., F. Isaka, M. Ishibashi, K. Tomita, H. Tsuda, S. Nakanishi, and R. Kageyama. 1998. Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and enhancer of split. Genomics 49:69–75.
   PubMedGoogle Scholar
• Ohtsuka, T., M. Ishibashi, G. Gradwohl, S. Nakanishi, F. Guillemot, and R. Kageyama. 1999. Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J. 18:2196–2207.
   PubMedGoogle Scholar
• Onishi, M., S. Kinoshita, Y. Morikawa, A. Shibuya, J. Phillips, L. L. Lanier, D. M. Gorman, G. P. Nolan, A. Miyajima, and T. Kitamura. 1996. Applications of retrovirus-mediated expression cloning. Exp. Hematol. 24:324–329.
   PubMed Web of Science ®Google Scholar
• Petcherski, A. G., and J. Kimble. 2000. LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway. Nature 405:364–368.
   PubMed Web of Science ®Google Scholar
• Petcherski, A. G., and J. Kimble. 2000. Mastermind is a putative activator for Notch. Curr. Biol. 10:R471–R473.
   PubMed Web of Science ®Google Scholar
• Ruvkun, G., and O. Hobert. 1998. The taxonomy of developmental control in Caenorhabditis elegans. Science 282:2033–2041.
   PubMedGoogle Scholar
• Sakai, T., T. Furukawa, H. Iwanari, C. Oka, T. Nakano, M. Kawaichi, and T. Honjo. 1995. Loss of immunostaining of the RBP-J kappa transcription factor upon F9 cell differentiation induced by retinoic acid. J. Biochem. (Tokyo) 118:621–628.
   PubMedGoogle Scholar
• Schroeter, E. H., J. A. Kisslinger, and R. Kopan. 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393:382–386.
   PubMed Web of Science ®Google Scholar
• Sestan, N., S. Artavanis-Tsakonas, and P. Rakic. 1999. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 286:741–746.
   PubMed Web of Science ®Google Scholar
• Smoller, D., C. Friedel, A. Schmid, D. Bettler, L. Lam, and B. Yedvobnick. 1990. The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers. Genes Dev. 4:1688–1700.
   PubMed Web of Science ®Google Scholar
• Struhl, G., and A. Adachi. 1998. Nuclear access and action of notch in vivo. Cell 93:649–660.
   PubMed Web of Science ®Google Scholar
• Su, W. C., M. Kitagawa, N. Xue, B. Xie, S. Garofalo, J. Cho, C. Deng, W. A. Horton, and X. Y. Fu. 1997. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature 386:288–292.
   PubMed Web of Science ®Google Scholar
• Takebayashi, K., Y. Sasai, Y. Sakai, T. Watanabe, S. Nakanishi, and R. Kageyama. 1994. Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements. J. Biol. Chem. 269:5150–5156.
   PubMedGoogle Scholar
• Taniguchi, Y., T. Furukawa, T. Tun, H. Han, and T. Honjo. 1998. LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein. Mol. Cell. Biol. 18:644–654.
   PubMed Web of Science ®Google Scholar
• Weinmaster, G.. 2000. Notch signal transduction: a real rip and more. Curr. Opin. Genet. Dev. 10:363–369.
   PubMed Web of Science ®Google Scholar
• Wharton, K. A., K. M. Johansen, T. Xu, and S. Artavanis-Tsakonas. 1985. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell 43:567–581.
   PubMed Web of Science ®Google Scholar
• Wu, L., J. C. Aster, S. C. Blacklow, R. Lake, S. Artavanis-Tsakonas, and J. D. Griffin. 2000. MAML1, a human homologue of drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat. Genet. 26:484–489.
   PubMed Web of Science ®Google Scholar