Regulation of Alternative Splicing by the ATP-Dependent DEAD-Box RNA Helicase p72

REFERENCES

• Arning, S., P. Gruter, G. Bilbe, and A. Kramer. 1996. Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA. RNA 2: 794–810.
   PubMed Web of Science ®Google Scholar
• Caruthers, J. M., and D. B. McKay. 2002. Helicase structure and mechanism. Curr. Opin. Struct. Biol. 12: 123–133.
   PubMed Web of Science ®Google Scholar
• Chen, J. Y., L. Stands, J. P. Staley, R. R. Jackups, L. J. Latus, and T. H. Chang. 2001. Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor. Mol. Cell 7: 227–232.
   PubMed Web of Science ®Google Scholar
• de la Cruz, J., D. Kressler, and P. Linder. 1999. Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem. Sci. 24: 192–199.
   PubMed Web of Science ®Google Scholar
• Dominski, Z., and R. Kole. 1992. Cooperation of pre-RNA sequence elements in splice site selection. Mol. Cell. Biol. 12: 2108–2114.
   PubMed Web of Science ®Google Scholar
• Dominski, Z., and R. Kole. 1994. Identification of exon sequences involved in splice site selection. J. Biol. Chem. 269: 23590–23596.
   PubMedGoogle Scholar
• Endoh, H., K. Maruyama, Y. Masuhiro, Y. Kobayashi, M. Goto, H. Tai, J. Yanagisawa, D. Metzger, S. Hashimoto, and S. Kato. 1999. Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor α. Mol. Cell. Biol. 19: 5363–5372.
   PubMed Web of Science ®Google Scholar
• Ge, H., P. Zuo, and J. L. Manley. 1991. Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell 26: 373–382.
   Google Scholar
• Ghisolfi, L., G. Joseph, F. Amalric, and M. Erard. 1992. The glycine-rich domain of nucleolin has an unusual supersecondary structure responsible for its RNA-helix-destabilizing properties. J. Biol. Chem. 267: 2955–2959.
   PubMed Web of Science ®Google Scholar
• Günthert, U. 1993. CD44: a multitude of isoforms with diverse functions. Curr. Top. Microbiol. Immunol. 184: 47–63.
   PubMedGoogle Scholar
• Hamm, J., and A. I. Lamond. 1998. Spliceosome assembly: the unwinding role of DEAD-box proteins. Curr. Biol. 8: R532–R534.
   PubMedGoogle Scholar
• Hirling, H., M. Scheffner, T. Restele, and H. Stahl. 1989. RNA helicase activity associated with the human p68 protein. Nature 339: 562–564.
   PubMed Web of Science ®Google Scholar
• Iggo, R. D., and D. P. Lane. 1989. Nuclear protein p68 is an RNA-dependent ATPase. EMBO J. 8: 1827–1831.
   PubMed Web of Science ®Google Scholar
• Iggo, R. D., D. J. Jamieson, S. A. MacNeill, J. Southgate, J. McPheat, and D. P. Lane. 1991. p68 RNA helicase: identification of a nucleolar forma and cloning of related genes containing a conserved intron in yeasts. Mol. Cell. Biol. 11: 1326–1333.
   PubMedGoogle Scholar
• Jankowsky, E., C. H. Gross, S. Shuman, and A. M. Pyle. 2001. Active disruption of an RNA-protein interaction by a DExH/D RNA helicase. Science 291: 121–124.
   PubMedGoogle Scholar
• Jiang, Z., J. Cote, J. W. Kwon, A. M. Goate, and J. Y. Wu. 2000. Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17. Mol. Cell. Biol. 20: 4036–4048.
   PubMedGoogle Scholar
• Kiledjian, M., and G. Dreyfuss. 1992. Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. EMBO J. 11: 2655–2664.
   PubMed Web of Science ®Google Scholar
• Kistler, A. L., and C. Guthrie. 2001. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomeal ATPase. Genes Dev. 15: 42–49.
   PubMed Web of Science ®Google Scholar
• König, H., H. Ponta, and P. Herrlich. 1998. Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator. EMBO J. 17: 2904–2913.
   PubMedGoogle Scholar
• Krainer, A. R., A. Mayeda, D. Kozak, and G. Binns. 1991. Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins U1 70K and Drosophila splicing regulators. Cell 66: 383–394.
   PubMed Web of Science ®Google Scholar
• Krecic, A. M., and M. S. Swanson. 1999. hnRNP complexes: composition, structure, and function. Curr. Opin. Cell Biol. 11: 363–371.
   PubMed Web of Science ®Google Scholar
• Lamm, G. M., S. M. Nicol, F. V. Fuller-Pace, and A. I. Lamond. 1996. p72: a human nuclear DEAD box protein highly related to p68. Nucleic Acids Res. 24: 3739–3747.
   PubMed Web of Science ®Google Scholar
• Lanz, R. B., N. J. McKenna, S. A. Onate, U. Albrecht, J. Wong, S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. 1999. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell 97: 17–27.
   PubMed Web of Science ®Google Scholar
• Linder, P., N. K. Tanner, and J. Banroques. 2001. From RNA helicases to RNPases. Trends Biochem. Sci. 26: 339–340.
   PubMedGoogle Scholar
• Lorsch, J. R., and D. Herschlag. 1998. The DEAD box protein eIF4A. 2. A cycle of nucleotide and RNA-dependent conformational changes. Biochemistry 37: 2194–2206.
   PubMed Web of Science ®Google Scholar
• Lou, H., R. F. Gagel, and S. M. Berget. 1996. An intron enhancer recognized by splicing factors activates polyadenylation. Genes Dev. 10: 208–219.
   PubMedGoogle Scholar
• Lou, H., D. M. Helfman, R. F. Gagel, and S. M. Berget. 1999. Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3′-terminal exon. Mol. Cell. Biol. 19: 1978–1985.
   Google Scholar
• Luking, A., U. Stahl, and U. Schmidt. 1998. The protein family of RNA helicases. Crit. Rev. Biochem. Mol. Biol. 33: 259–296.
   PubMed Web of Science ®Google Scholar
• McCullough, A. J., and S. M. Berget. 1997. G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selection. Mol. Cell. Biol. 17: 4562–4571.
   PubMedGoogle Scholar
• Neubauer, G., A. King, J. Rappsilber, C. Calvio, M. Watson, P. Ajuh, J. Sleeman, A. Lamond, and M. Mann. 1998. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. Nat. Genet. 20: 46–50.
   PubMed Web of Science ®Google Scholar
• Ohno, M., and Y. Shimura. 1996. A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. Genes Dev. 10: 997–1007.
   PubMedGoogle Scholar
• Patton, J. G., E. B. Porro, J. Galceran, P. Tempst, and B. Nadal-Ginard. 1993. Cloning and characterization of PSF, a novel pre-mRNA splicing factor. Genes Dev. 7: 393–406.
   PubMedGoogle Scholar
• Pinol-Roma, S., M. S. Swanson, J. G. Gall, and G. Dreyfuss. 1989. A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts. J. Cell Biol. 109: 2575–2587.
   PubMedGoogle Scholar
• Ramchatesingh, J., A. M. Zahler, K. M. Neugebauer, M. B. Roth, and T. A. Cooper. 1995. A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Mol. Cell. Biol. 15: 4898–4907.
   PubMed Web of Science ®Google Scholar
• Schwer, B. 2001. A new twist on RNA helicases: DExH/D box proteins as RNPases. Nat. Struct. Biol. 8: 113–116.
   PubMedGoogle Scholar
• Schwer, B., and T. Meszaros. 2000. RNA helicase dynamics in pre-mRNA splicing. EMBO J. 23: 6582–6591.
   Google Scholar
• Screaton, G. R., M. V. Bell, D. G. Jackson, F. B. Cornelis, U. Gerth, and J. I. Bell. 1992. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc. Natl. Acad. Sci. USA 89: 12160–12164.
   PubMed Web of Science ®Google Scholar
• Sillekens, P. T., R. P. Beijer, W. J. Habets, and W. J. Venrooij. 1988. Human U1 snRNP-specific C protein: complete cDNA and protein sequence and identification of a multigene family in mammals. Nucleic Acids Res. 16: 8307–8321.
   PubMed Web of Science ®Google Scholar
• Sillekens, P. T., W. J. Habets, R. P. Beijer, and W. J. Venrooij. 1987. cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP proteins. EMBO J. 6: 3841–3848.
   PubMed Web of Science ®Google Scholar
• Staley, J. P., and C. Guthrie. 1998. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92: 315–326.
   PubMed Web of Science ®Google Scholar
• Stickeler, E., S. D. Fraser, A. Honig, A. L. Chen, S. M. Berget, and T. A. Cooper. 2001. The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. EMBO J. 20: 3821–3830.
   PubMedGoogle Scholar
• Tafuri, S. T., and A. P. Wolffe. 1990. Xenopus Y-box-binding transcription factors: molecular cloning, functional analysis and developmental regulation. Proc. Natl. Acad. Sci. USA 87: 9028–9032.
   PubMed Web of Science ®Google Scholar
• Watanabe, M., J. Yanagisawa, H. Kitagawa, K. Takeyama, S. Ogawa, Y. Arao, M. Suzawa, Y. Kobayashi, T. Yano, H. Yoshikawa, Y. Masuhiro, and S. Kato. 2001. A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor α coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. EMBO J. 20: 1341–1352.
   PubMedGoogle Scholar
• Will, C. L., and R. Luhrmann. 2001. Molecular biology: RNP remodeling with DexH/D boxes. Science 291: 1916–1917.
   PubMedGoogle Scholar
• Zhang, M., P. D. Zamore, M. Carmo-Fonseca, A. I. Lamond, and M. R. Green. 1992. Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc. Natl. Acad. Sci. USA 89: 8769–8773.
   PubMed Web of Science ®Google Scholar