Deficiency in SNM1 Abolishes an Early Mitotic Checkpoint Induced by Spindle Stress

REFERENCES

• Anderson, L., Henderson C., and Adachi Y.. 2001. Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage. Mol. Cell. Biol. 21:1719–1729.
   PubMed Web of Science ®Google Scholar
• Andreassen, P. R., Lohez O. D., Lacroix F. B., and Margolis R. L.. 2001. Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol. Biol. Cell 12:1315–1328.
   PubMed Web of Science ®Google Scholar
• Bleicher, R. J., Xia H., Zaren H. A., and Singh S. V.. 2000. Biochemical mechanism of cross resistance to paclitaxel in a mitomycin C-resistant human bladder cancer cell line. Cancer Lett. 150:129–135.
   PubMedGoogle Scholar
• Callebaut, I., Moshous D., Mornon J. P., and de Villartay J. P.. 2002. Metallo-β-lactamase fold within nucleic acids processing enzymes: the β-CASP family. Nucleic Acids Res. 30:3592–3601.
   PubMed Web of Science ®Google Scholar
• Cerutti, L., and Simanis V.. 2000. Controlling the end of the cell cycle. Curr. Opin. Genet. Dev. 9:65–69.
   Google Scholar
• Chang, D. C., Xu N., and Luo K. Q.. 2003. Degradation of cyclin B is required for the onset of anaphase in mammalian cells. J. Biol. Chem. 278:37865–37873.
   PubMed Web of Science ®Google Scholar
• Cleveland, D. W., Mao Y., and Sullivan K. F.. 2003. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112:407–421.
   PubMed Web of Science ®Google Scholar
• Digue, L., Orsiere T., De Meo M., Mattei M. G., Depetris D., Duffaud F., Favre R., and Botta A.. 1999. Evaluation of the genotoxic activity of paclitaxel by the in vitro micronucleus test in combination with fluorescent in situ hybridization of a DNA centromeric probe and the alkaline single cell gel electrophoresis technique (comet assay) in human T-lymphocytes. Environ. Mol. Mutagen. 34:269–278.
   PubMed Web of Science ®Google Scholar
• Dronkert, M. L., de Wit J., Boeve M., Vasconcelos M. L., van Steeg H. T., Tan L., Hoeijmakers J. H., and Kanaar R.. 2000. Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C. Mol. Cell. Biol. 20:4553–4561.
   PubMedGoogle Scholar
• Geley, S., Kramer E., Gieffers C., Gannon J., Peters J.-M., and Hunt T.. 2001. Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. J. Cell Biol. 153:137–147.
   PubMed Web of Science ®Google Scholar
• Henriques, J. A., and Moustacchi E.. 1980. Isolation and characterization of pso mutants sensitive to photoaddition of psoralen derivatives in Saccharomyces cerevisiae. Genetics 95:273–288.
   PubMedGoogle Scholar
• Horan, G. S., Kovacs E. N., Behringer R. R., and Featherstone M. S.. 1995. Mutations in paralogous Hox genes result in overlapping homeotic transformations of the axial skeleton: evidence for unique and redundant function. Dev. Biol. 169:359–372.
   PubMedGoogle Scholar
• Hut, H. M. J., Lemstra W., Blaauw E. H., van Cappellen G. W. A., Kampinga H. H., and Sibon O. C. M.. 2003. Centrosomes split in the presence of impaired DNA integrity during mitosis. Mol. Biol. Cell 14:1993–2004.
   PubMed Web of Science ®Google Scholar
• Jenny, A., Minvielle-Sebastia L., Preker P. J., and Keller W.. 1996. Sequence similarity between the 73-kilodalton protein of mammalian CPSF and a subunit of yeast polyadenylation factor I. Science 274:5292–5293.
   Google Scholar
• Jullien, D., Vagnarelli P., Earnshaw W. C., and Adachi Y.. 2002. Kinetochore localisation of the DNA damage response component 53BP1 during mitosis. J. Cell Sci. 115:71–79.
   PubMed Web of Science ®Google Scholar
• Kang, D., Chen J., Wong J., and Fang G.. 2002. The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition. J. Cell Biol. 156:249–259.
   PubMed Web of Science ®Google Scholar
• Lanni, J. S., and Jacks T.. 1998. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol. Cell. Biol. 18:1055–1064.
   PubMed Web of Science ®Google Scholar
• Liu, X., and Erikson R. L.. 2002. Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA. Proc. Natl. Acad. Sci. USA 99:8672–8676.
   PubMed Web of Science ®Google Scholar
• Magana-Schwencke, N., Henriques J. A., Chanet R., and Moustacchi E.. 1982. The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: comparison of wild-type and repair-deficient strains. Proc. Natl. Acad. Sci. USA 79:1722–1726.
   PubMed Web of Science ®Google Scholar
• Meniel, V., Magana-Schwencke N., and Averbeck D.. 1995. Preferential repair in Saccharomyces cerevisiae rad mutants after induction of interstrand cross-links by 8-methoxypsoralen plus UVA. Mutagenesis 10:543–548.
   PubMedGoogle Scholar
• Michel, L. S., Liberal V., Chatterjee A., Kirchwegger R., Pasche B., Gerald W., Dobles M., Sorger P. K., and Benezra R.. 2001. MAD2 haploinsufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature 409:355–359.
   PubMed Web of Science ®Google Scholar
• Mikhailov, A., and Rieder C. L.. 2002. Cell cycle: stressed out of mitosis. Curr. Biol. 12:R331–R333.
   PubMed Web of Science ®Google Scholar
• Moshous, D., Callebaut I., de Chasseval R., Corneo B., Cavazzana-Calvo M., Le Deist F., Tezcan I., Sanal O., Bertrand Y., Phillippe N., Fischer A., and de Villartay J. P.. 2001. Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105:177–186.
   PubMed Web of Science ®Google Scholar
• Muhua, L., Adames N. R., Murphy M. D., Shields C. R., and Cooper J. A.. 1998. A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein. Nature 393:487–491.
   PubMedGoogle Scholar
• Paull, T. T., Rogakou E. P., Yamazaki V., Kirchgessner C. U., Gellert M., and Bonner W. M.. 2000. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10:886–895.
   PubMed Web of Science ®Google Scholar
• Rappold, I., Iwabuchi K., Date T., and Chen J.. 2001. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J. Cell Biol. 153:613–620.
   PubMed Web of Science ®Google Scholar
• Richie, C. T., Peterson C. A., Lu T., Hittelman W. N., Carpenter P. B., and Legerski R. J.. 2002. hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage. Mol. Cell. Biol. 22:8635–8647.
   PubMedGoogle Scholar
• Ruhland, A., Kircher M., Wilborn F., and Brendel M.. 1981. A yeast mutant specifically sensitive to bifunctional alkylation. Mutat. Res. 91:457–462.
   PubMedGoogle Scholar
• Schultz, L. B., Chehab N. H., Malikzay A., and Halazonetis T. D.. 2000. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol. 151:1381–1390.
   PubMed Web of Science ®Google Scholar
• Scolnick, D. M., and Halazonetis T. D.. 2000. Chfr defines a mitotic stress checkpoint that delays entry into metaphase. Nature 406:430–435.
   PubMed Web of Science ®Google Scholar
• Shah, J. V., and Cleveland D. W.. 2000. Waiting for anaphase: Mad2 and the spindle assembly checkpoint. Cell 103:997–1000.
   PubMed Web of Science ®Google Scholar
• Shibata, Y., Haruki N., Kuwabara Y., Ishiguro H., Shinoda N., Sato A., Kimura M., Koyama H., Toyama T., Nishiwaki T., Kudo J., Terashita Y., Konishi S., Sugiura H., and Fujii Y.. 2002. Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer. Carcinogenesis 23:1695–1699.
   PubMedGoogle Scholar
• Smith, P. L., Gimenez-Abian J. F., and Clarke D. J.. 2002. DNA-damage-independent checkpoints: yeast and higher eukaryotes. Cell Cycle 1:16–33.
   PubMedGoogle Scholar
• Song, M. S., Song S. J., Ayad N. G., Chang J. S., Lee J. H., Hong H. K., Lee H., Choi N., Kim J., Kim H., Kim J. W., Choi E.-J., Kirschner M. W., and Lim D.-S.. 2004. The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex. Nat. Cell Biol. 6:129–137.
   PubMed Web of Science ®Google Scholar
• Sudo, T., Ota Y., Kotani S., Nakao M., Takami Y., Takeda S., and Saya H.. 2001. Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells. EMBO J. 20:6499–6508.
   PubMed Web of Science ®Google Scholar
• Takada, S., Kelkar A., and Theurkauf W. E.. 2003. Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity. Cell 113:87–99.
   PubMed Web of Science ®Google Scholar
• Tavtigian, S. V., Simard J., Teng D. H., Abtin V., Baumgard M., Beck A., Camp N. J., Carillo A. R., Chen Y., Dayananth P., Desrochers M., Dumont M., Farnham J. M., Frank D., Frye C., Ghaffari S., Gupte J. S., Hu R., Iliev D., Janecki T., Kort N., Laity K. E., Leavitt A., Leblanc G., McArthur-Morrison G., Pederson A., Penn B., Peterson K. T., Reid J. E., Richards S., Schroeder M., Smith R., Snyder S. C., Swedlund B., Swensen B., Thomas A., Tranchant M., Woodland A. M., Labrie F., Skolnick M. H., Neuhausen S., Rommens J., and Cannon-Albright L. A.. 2001. A candidate prostate cancer susceptibility gene at chromosome 17p. Nat. Genet. 27:172–180.
   PubMed Web of Science ®Google Scholar
• Wang, Y., Cortez D., Yazdi P., Neff N., Elledge S. J., and Qin J.. 2000. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 14:927–939.
   PubMed Web of Science ®Google Scholar
• Xia, Z., Morales J. C., Dunphy W. G., and Carpenter P. B.. 2001. Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1. J. Biol. Chem. 276:2708–2718.
   PubMed Web of Science ®Google Scholar
• Zhang, X., Richie C. T., and Legerski R. J.. 2002. Translation of hSNM1is mediated by an internal ribosome entry site that upregulates expression during mitosis. DNA Repair 1:379–390.
   PubMedGoogle Scholar