CRAC inhibitors: identification and potential

Bibliography

• Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 2003;4:517-29
   PubMed Web of Science ®Google Scholar
• Parekh AB. Cell biology: cracking the calcium entry code. Nature 2006;441:163-5
   PubMed Web of Science ®Google Scholar
• Parekh AB. A CRAC current tango. Nat Cell Biol 2006;8:655-6
   PubMed Web of Science ®Google Scholar
• Parekh AB, Putney JW Jr. Store-operated calcium channels. Physiol Rev 2005;85:757-810
   PubMed Web of Science ®Google Scholar
• Spassova MA, Soboloff J, He LP, et al. Calcium entry mediated by SOCs and TRP channels: variations and enigma. Biochim Biophys Acta 2004;1742:9-20
   PubMed Web of Science ®Google Scholar
• Dutta D. Mechanism of store-operated calcium entry. J Biosci 2000;25:397-404
   PubMed Web of Science ®Google Scholar
• Chakrabarti R, Chakrabarti R. Calcium signaling in non-excitable cells: Ca2+ release and influx are independent events linked to two plasma membrane Ca2+ entry channels. J Cell Biochem 2006;99:1503-16
   PubMed Web of Science ®Google Scholar
• Prakriya M, Lewis RS. CRAC channels: activation, permeation, and the search for a molecular identity. Cell Calcium 2003;33:311-21
   PubMed Web of Science ®Google Scholar
• Hoth M, Penner R. Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 1992;355:353-6
   PubMed Web of Science ®Google Scholar
• Smani T, Zakharov SI, Leno E, et al. Ca2+-independent phospholipase A2 is a novel determinant of store-operated Ca2+ entry. J Biol Chem 2003;278:11909-15
   PubMed Web of Science ®Google Scholar
• Zakharov SI, Smani T, Dobrydneva Y, et al. Diethylstilbestrol is a potent inhibitor of store-operated channels and capacitative Ca(2+) influx. Mol Pharmacol 2004;66:702-7
   PubMed Web of Science ®Google Scholar
• Skryma R, Mariot P, Bourhis XL, et al. Store depletion and store-operated Ca2+ current in human prostate cancer LNCaP cells: involvement in apoptosis. J Physiol 2000;527(Pt 1):71-83
   PubMed Web of Science ®Google Scholar
• Putney JW Jr, Broad LM, Braun FJ, et al. Mechanisms of capacitative calcium entry. J Cell Sci 2001;114:2223-9
   PubMed Web of Science ®Google Scholar
• Franzius D, Hoth M, Penner R. Non-specific effects of calcium entry antagonists in mast cells. Pflugers Arch 1994;428:433-8
   PubMed Web of Science ®Google Scholar
• Cahalan MD, Chandy KG. Ion channels in the immune system as targets for immunosuppression. Curr Opin Biotechnol 1997;8:749-56
   PubMed Web of Science ®Google Scholar
• Panyi G, Varga Z, Gaspar R. Ion channels and lymphocyte activation. Immunol Lett 2004;92:55-66
   PubMed Web of Science ®Google Scholar
• Buckley RH. The multiple causes of human SCID. J Clin Invest 2004;114:1409-11
   PubMed Web of Science ®Google Scholar
• Carroll HP, McNaull BB, Gadina M. Immunodeficiency is a tough nut to CRAC: the importance of calcium flux in T cell activation. Mol Interv 2006;6:253-6
   PubMed Web of Science ®Google Scholar
• Gaspar HB, Gilmour KC, Jones AM. Severe combined immunodeficiency – molecular pathogenesis and diagnosis. Arch Dis Child 2001;84:169-73
   PubMed Web of Science ®Google Scholar
• Gaspar HB, Thrasher AJ. Gene therapy for severe combined immunodeficiencies. Expert Opin Biol Ther 2005;5:1175-82
   PubMed Web of Science ®Google Scholar
• Gwack Y, Feske S, Srikanth S, et al. Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes. Cell Calcium 2007;42:145-56
   PubMed Web of Science ®Google Scholar
• Flechner SM, Kobashigawa J, Klintmalm G. Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity. Clin Transplant 2008;22:1-15
   PubMed Web of Science ®Google Scholar
• Al-Mohaya M, Treister N, Al-Khadra O, et al. Calcineurin inhibitor-associated oral inflammatory polyps after transplantation. J Oral Pathol Med 2007;36:570-4
   PubMed Web of Science ®Google Scholar
• Soboloff J, Spassova MA, Tang XD, et al. Orai1 and STIM reconstitute store-operated calcium channel function. J Biol Chem 2006;281:20661-5
   PubMed Web of Science ®Google Scholar
• Peinelt C, Vig M, Koomoa DL, et al. Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nat Cell Biol 2006;8:771-3
   PubMed Web of Science ®Google Scholar
• Feske S, Gwack Y, Prakriya M, et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 2006;441:179-85
   PubMed Web of Science ®Google Scholar
• Hoth M, Penner R. Calcium release-activated calcium current in rat mast cells. J Physiol 1993;465:359-86
   PubMed Web of Science ®Google Scholar
• Ross PE, Cahalan MD. Ca2+ influx pathways mediated by swelling or stores depletion in mouse thymocytes. J Gen Physiol 1995;106:415-44
   PubMed Web of Science ®Google Scholar
• Trebak M, Bird GS, McKay RR, Putney JW Jr. Comparison of human TRPC3 channels in receptor-activated and store-operated modes. Differential sensitivity to channel blockers suggests fundamental differences in channel composition. J Biol Chem 2002;277:21617-23
   PubMed Web of Science ®Google Scholar
• Krause E, Pfeiffer F, Schmid A, Schulz I. Depletion of intracellular calcium stores activates a calcium conducting nonselective cation current in mouse pancreatic acinar cells. J Biol Chem 1996;271:32523-8
   PubMed Web of Science ®Google Scholar
• Merritt JE, Armstrong WP, Benham CD, et al. SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem J 1990;271:515-22
   PubMed Web of Science ®Google Scholar
• Chung SC, McDonald TV, Gardner P. Inhibition by SK&F 96365 of Ca2+ current, IL-2 production and activation in T lymphocytes. Br J Pharmacol 1994;113:861-8
   PubMed Web of Science ®Google Scholar
• Prakriya M, Lewis RS. Separation and characterization of currents through store-operated CRAC channels and Mg2+-inhibited cation (MIC) channels. J Gen Physiol 2002;119:487-507
   PubMed Web of Science ®Google Scholar
• Kozak JA, Kerschbaum HH, Cahalan MD. Distinct properties of CRAC and MIC channels in RBL cells. J Gen Physiol 2002;120:221-35
   PubMed Web of Science ®Google Scholar
• Estevez AY, Roberts RK, Strange K. Identification of store-independent and store-operated Ca2+ conductances in Caenorhabditis elegans intestinal epithelial cells. J Gen Physiol 2003;122:207-23
   PubMed Web of Science ®Google Scholar
• Daly JW, Lueders J, Padgett WL, et al. Maitotoxin-elicited calcium influx in cultured cells. Effect of calcium-channel blockers. Biochem Pharmacol 1995;50:1187-97
   PubMed Web of Science ®Google Scholar
• Mazzei GJ, Schatzman RC, Turner RS, et al. Phospholipid-sensitive Ca2+-dependent protein kinase inhibition by R-24571, a calmodulin antagonist. Biochem Pharmacol 1984;33:125-30
   PubMed Web of Science ®Google Scholar
• Harper JL, Daly JW. Effect of calmidazolium analogs on calcium influx in HL-60 cells. Biochem Pharmacol 2000;60:317-24
   PubMed Web of Science ®Google Scholar
• Ciardo A, Meldolesi J. Multiple actions of SC 38249: the blocker of both voltage-operated and second messenger-operated Ca2+ channels also inhibits Ca2+ extrusion. Eur J Pharmacol 1990;188:417-21
   PubMed Web of Science ®Google Scholar
• Alvarez J, Montero M, Garcia-Sancho J. High affinity inhibition of Ca(2+)-dependent K+ channels by cytochrome P-450 inhibitors. J Biol Chem 1992;267:11789-93
   PubMed Web of Science ®Google Scholar
• Schwarz G, Droogmans G, Nilius B. Multiple effects of SK&F 96365 on ionic currents and intracellular calcium in human endothelial cells. Cell Calcium 1994;15:45-54
   PubMed Web of Science ®Google Scholar
• Capdevila J, Gil L, Orellana M, et al. Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism. Arch Biochem Biophys 1988;261:257-63
   PubMed Web of Science ®Google Scholar
• Rodrigues AD, Gibson GG, Ioannides C, Parke DV. Interactions of imidazole antifungal agents with purified cytochrome P-450 proteins. Biochem Pharmacol 1987;36:4277-81
   PubMed Web of Science ®Google Scholar
• Mason MJ, Mayer B, Hymel LJ. Inhibition of Ca2+ transport pathways in thymic lymphocytes by econazole, miconazole, and SKF 96365. Am J Physiol 1993;264:C654-62
   PubMed Web of Science ®Google Scholar
• Sugawara H, Kurosaki M, Takata M, Kurosaki T. Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor. EMBO J 1997;16:3078-88
   PubMed Web of Science ®Google Scholar
• Ma HT, Patterson RL, van Rossum DB, et al. Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels. Science 2000;287:1647-51
   PubMed Web of Science ®Google Scholar
• Bakowski D, Burgoyne RD, Parekh AB. Activation of the store-operated calcium current ICRAC can be dissociated from regulated exocytosis in rat basophilic leukaemia (RBL-1) cells. J Physiol 2003;553:387-93
   PubMed Web of Science ®Google Scholar
• Bakowski D, Glitsch MD, Parekh AB. An examination of the secretion-like coupling model for the activation of the Ca2+ release-activated Ca2+ current I(CRAC) in RBL-1 cells. J Physiol 2001;532:55-71
   PubMed Web of Science ®Google Scholar
• Broad LM, Braun FJ, Lievremont JP, et al. Role of the phospholipase C-inositol 1,4,5-trisphosphate pathway in calcium release-activated calcium current and capacitative calcium entry. J Biol Chem 2001;276:15945-52
   PubMed Web of Science ®Google Scholar
• Ma HT, Venkatachalam K, Li HS, et al. Assessment of the role of the inositol 1,4,5-trisphosphate receptor in the activation of transient receptor potential channels and store-operated Ca2+ entry channels. J Biol Chem 2001;276:18888-96
   PubMed Web of Science ®Google Scholar
• Prakriya M, Lewis RS. Potentiation and inhibition of Ca(2+) release-activated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP 3;receptors. J Physiol 2001;536:3-19
   PubMed Web of Science ®Google Scholar
• Missiaen L, Van Acker K, Van Baelen K, et al. Calcium release from the Golgi apparatus and the endoplasmic reticulum in HeLa cells stably expressing targeted aequorin to these compartments. Cell Calcium 2004;36:479-87
   PubMed Web of Science ®Google Scholar
• Wang Y, Deshpande M, Payne R. 2-Aminoethoxydiphenyl borate inhibits phototransduction and blocks voltage-gated potassium channels in Limulus ventral photoreceptors. Cell Calcium 2002;32:209-16
   PubMed Web of Science ®Google Scholar
• Hermosura MC, Monteilh-Zoller MK, Scharenberg AM, et al. Dissociation of the store-operated calcium current I(CRAC) and the Mg-nucleotide-regulated metal ion current MagNuM. J Physiol 2002;539:445-58
   PubMed Web of Science ®Google Scholar
• Chung MK, Lee H, Mizuno A, et al. 2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J Neurosci 2004;24:5177-82
   PubMed Web of Science ®Google Scholar
• Delmas P. Assembly and gating of TRPC channels in signalling microdomains. Novartis Found Symp 2004;258:75-89; discussion 89-102, 263-106
   PubMedGoogle Scholar
• Xu SZ, Zeng F, Boulay G, et al. Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect. Br J Pharmacol 2005;145:405-14
   PubMed Web of Science ®Google Scholar
• Lievremont JP, Bird GS, Putney JW Jr. Mechanism of inhibition of TRPC cation channels by 2-aminoethoxydiphenylborane. Mol Pharmacol 2005;68:758-62
   PubMed Web of Science ®Google Scholar
• Diver JM, Sage SO, Rosado JA. The inositol trisphosphate receptor antagonist 2-aminoethoxydiphenylborate (2-APB) blocks Ca2+ entry channels in human platelets: cautions for its use in studying Ca2+ influx. Cell Calcium 2001;30:323-9
   PubMed Web of Science ®Google Scholar
• Voets T, Prenen J, Fleig A, et al. CaT1 and the calcium release-activated calcium channel manifest distinct pore properties. J Biol Chem 2001;276:47767-70
   PubMed Web of Science ®Google Scholar
• Schindl R, Kahr H, Graz I, et al. Store depletion-activated CaT1 currents in rat basophilic leukemia mast cells are inhibited by 2-aminoethoxydiphenyl borate. Evidence for a regulatory component that controls activation of both CaT1 and CRAC (Ca(2+) release-activated Ca(2+) channel) channels. J Biol Chem 2002;277:26950-8
   PubMed Web of Science ®Google Scholar
• Nilius B, Prenen J, Vennekens R, et al. Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1. Br J Pharmacol 2001;134:453-62
   PubMed Web of Science ®Google Scholar
• Hinman A, Chuang HH, Bautista DM, Julius D. TRP channel activation by reversible covalent modification. Proc Natl Acad Sci USA 2006;103:19564-8
   PubMed Web of Science ®Google Scholar
• Kim D, Cavanaugh EJ. Requirement of a soluble intracellular factor for activation of transient receptor potential A1 by pungent chemicals: role of inorganic polyphosphates. J Neurosci 2007;27:6500-9
   PubMed Web of Science ®Google Scholar
• Fischer BS, Qin D, Kim K, McDonald TV. Capsaicin inhibits Jurkat T-cell activation by blocking calcium entry current I(CRAC). J Pharmacol Exp Ther 2001;299:238-46
   PubMed Web of Science ®Google Scholar
• Cui J, Bian JS, Kagan A, McDonald TV. CaT1 contributes to the stores-operated calcium current in Jurkat T-lymphocytes. J Biol Chem 2002;277:47175-83
   PubMed Web of Science ®Google Scholar
• Turner H, Fleig A, Stokes A, et al. Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity. Biochem J 2003;371:341-50
   PubMed Web of Science ®Google Scholar
• Gericke M, Oike M, Droogmans G, Nilius B. Inhibition of capacitative Ca2+ entry by a Cl- channel blocker in human endothelial cells. Eur J Pharmacol 1994;269:381-4
   PubMed Web of Science ®Google Scholar
• Reinsprecht M, Rohn MH, Spadinger RJ, et al. Blockade of capacitive Ca2+ influx by Cl- channel blockers inhibits secretion from rat mucosal-type mast cells. Mol Pharmacol 1995;47:1014-20
   PubMed Web of Science ®Google Scholar
• Li JH, Spence KT, Dargis PG, Christian EP. Properties of Ca(2+) release-activated Ca(2+) channel block by 5-nitro-2-(3-phenylpropylamino)-benzoic acid in Jurkat cells. Eur J Pharmacol 2000;394:171-9
   PubMed Web of Science ®Google Scholar
• Chandy KG, Wulff H, Beeton C, et al. K+ channels as targets for specific immunomodulation. Trends Pharmacol Sci 2004;25:280-9
   PubMed Web of Science ®Google Scholar
• Ishikawa J, Ohga K, Yoshino T, et al. A pyrazole derivative, YM-58483, potently inhibits store-operated sustained Ca2+ influx and IL-2 production in T lymphocytes. J Immunol 2003;170:4441-9
   PubMed Web of Science ®Google Scholar
• Zitt C, Strauss B, Schwarz EC, et al. Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2. J Biol Chem 2004;279:12427-37
   PubMed Web of Science ®Google Scholar
• Takezawa R, Cheng H, Beck A, et al. A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity. Mol Pharmacol 2006;69:1413-20
   PubMed Web of Science ®Google Scholar
• He LP, Hewavitharana T, Soboloff J, et al. A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2. J Biol Chem 2005;280:10997-1006
   PubMed Web of Science ®Google Scholar
• Yoshino T, Ishikawa J, Ohga K, et al. YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models. Eur J Pharmacol 2007;560:225-33
   PubMed Web of Science ®Google Scholar
• Winstead MV, Balsinde J, Dennis EA. Calcium-independent phospholipase A(2): structure and function. Biochim Biophys Acta 2000;1488:28-39
   PubMed Web of Science ®Google Scholar
• Smani T, Zakharov SI, Csutora P, et al. A novel mechanism for the store-operated calcium influx pathway. Nat Cell Biol 2004;6:113-20
   PubMed Web of Science ®Google Scholar
• Aromataris EC, Castro J, Rychkov GY, Barritt GJ. Store-operated Ca(2+) channels and Stromal Interaction Molecule 1 (STIM1) are targets for the actions of bile acids on liver cells. Biochim Biophys Acta 2008;1783:74-85
   PubMed Web of Science ®Google Scholar
• Tran QK, Watanabe H, Le HY, et al. Myosin light chain kinase regulates capacitative ca(2+) entry in human monocytes/macrophages. Arterioscler Thromb Vasc Biol 2001;21:509-15
   PubMed Web of Science ®Google Scholar
• Soboloff J, Spassova MA, Dziadek MA, Gill DL. Calcium signals mediated by STIM and Orai proteins – a new paradigm in inter-organelle communication. Biochim Biophys Acta 2006;1763:1161-8
   PubMed Web of Science ®Google Scholar
• Liou J, Kim ML, Heo WD, et al. STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr Biol 2005;15:1235-41
   PubMed Web of Science ®Google Scholar
• Roos J, DiGregorio PJ, Yeromin AV, et al. STIM1, an essential and conserved component of store-operated Ca2+ channel function. J Cell Biol 2005;169:435-45
   PubMed Web of Science ®Google Scholar
• Zhang SL, Yu Y, Roos J, et al. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature 2005;437:902-5
   PubMed Web of Science ®Google Scholar
• Vig M, DeHaven WI, Bird GS, et al. Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels. Nat Immunol 2008;9:89-96
   PubMed Web of Science ®Google Scholar
• Baba Y, Nishida K, Fujii Y, et al. Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses. Nat Immunol 2008;9:81-8
   PubMed Web of Science ®Google Scholar
• Oh-Hora M, Yamashita M, Hogan PG, et al. Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance. Nat Immunol 2008;9:432-43
   PubMed Web of Science ®Google Scholar
• Stiber J, Hawkins A, Zhang ZS, et al. STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle. Nat Cell Biol 2008;10:688-97
   PubMed Web of Science ®Google Scholar
• Feske S, Giltnane J, Dolmetsch R, et al. Gene regulation mediated by calcium signals in T lymphocytes. Nat Immunol 2001;2:316-24
   PubMed Web of Science ®Google Scholar
• Mercer JC, Dehaven WI, Smyth JT, et al. Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J Biol Chem 2006;281:24979-90
   PubMed Web of Science ®Google Scholar
• Spassova MA, Soboloff J, He LP, et al. STIM1 has a plasma membrane role in the activation of store-operated Ca2+ channels. Proc Natl Acad Sci USA 2006;103:4040-5
   PubMed Web of Science ®Google Scholar
• Peinelt C, Lis A, Beck A, et al. 2-APB directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. J Physiol 2008 (In Press)
   PubMedGoogle Scholar
• Dehaven WI, Smyth JT, Boyles RR, et al. Complex actions of 2-aminoethyldiphenyl borate (2-APB) on store-operated calcium entry. J Biol Chem 2008 (In Press)
   Google Scholar
• Tamarina NA, Kuznetsov A, Philipson LH. Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting beta-cells. Cell Calcium 2008 (In Press)
   PubMedGoogle Scholar
• Gross SA, Wissenbach U, Philipp SE, et al. Murine ORAI2 splice variants form functional Ca2+ release-activated Ca2+ (CRAC) channels. J Biol Chem 2007;282:19375-84
   PubMed Web of Science ®Google Scholar
• Ma HT, Peng Z, Hiragun T, et al. Canonical transient receptor potential 5 channel in conjunction with Orai1 and STIM1 allows Sr2+ entry, optimal influx of Ca2+and degranulation in a rat mast cell line. J Immunol 2008;180:2233-9
   PubMed Web of Science ®Google Scholar
• Vanden Abeele F, Lemonnier L, Thebault S, et al. Two types of store-operated Ca2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells. J Biol Chem 2004;279:30326-37
   PubMed Web of Science ®Google Scholar
• Vanden Abeele F, Roudbaraki M, Shuba Y, et al. Store-operated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1. J Biol Chem 2003;278:15381-9
   PubMed Web of Science ®Google Scholar
• Kahr H, Schindl R, Fritsch R, et al. CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells. J Physiol 2004;557:121-32
   PubMed Web of Science ®Google Scholar
• Muik M, Frischauf I, Derler I, et al. Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. J Biol Chem 2008;283:8014-22
   PubMed Web of Science ®Google Scholar
• Spassova MA, Tanaka J, Hewavitharana T, et al. Voltage-gating at the selectivity filter of the CRAC channel induced by mutation of the Orai1 protein. J Biol Chem 2007;283:30326-37
   Google Scholar
• Lis A, Peinelt C, Beck A, et al. CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties. Curr Biol 2007;17:794-800
   PubMed Web of Science ®Google Scholar
• Zhang SL, Kozak JA, Jiang W, et al. Store-dependent and -independent modes regulating CRAC channel activity of human Orai1 and Orai3. J Biol Chem 2008 (In Press)
   Google Scholar
• Schindl R, Bergsmann J, Frischauf I, et al. 2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size. J Biol Chem 2008 (In Press)
   Google Scholar
• Vig M, Kinet JP. The long and arduous road to CRAC. Cell Calcium 2007;42:157-62
   PubMed Web of Science ®Google Scholar
• Brandman O, Liou J, Park WS, Meyer T. STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell 2007;131:1327-39
   PubMed Web of Science ®Google Scholar
• Parvez S, Beck A, Peinelt C, et al. STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation. FASEB J 2008;22:752-61
   PubMed Web of Science ®Google Scholar
• Grigoriev I, Gouveia SM, van der Vaart B, et al. STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol 2008;18:177-82
   PubMed Web of Science ®Google Scholar
• Baba Y, Hayashi K, Fujii Y, et al. Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum. Proc Natl Acad Sci USA 2006;103:16704-9
   PubMed Web of Science ®Google Scholar
• Smyth JT, DeHaven WI, Bird GS, Putney JW Jr. Role of the microtubule cytoskeleton in the function of the store-operated Ca2+ channel activator STIM1. J Cell Sci 2007;120:3762-71
   PubMed Web of Science ®Google Scholar
• Williams RT, Senior PV, Van Stekelenburg L, et al. Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation. Biochim Biophys Acta 2002;1596:131-7
   PubMed Web of Science ®Google Scholar
• Luik RM, Wu MM, Buchanan J, Lewis RS. The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. J Cell Biol 2006;174:815-25
   PubMed Web of Science ®Google Scholar
• Wu MM, Buchanan J, Luik RM, Lewis RS. Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. J Cell Biol 2006;174:803-13
   PubMed Web of Science ®Google Scholar
• Smyth JT, Dehaven WI, Bird GS, Putney JW Jr. Ca2+-store-dependent and -independent reversal of Stim1 localization and function. J Cell Sci 2008;121:762-72
   PubMed Web of Science ®Google Scholar
• Luik RM, Lewis RS. New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells. Trends Mol Med 2007;13:103-7
   PubMed Web of Science ®Google Scholar
• Stryer L, Haugland RP. Energy transfer: a spectroscopic ruler. Proc Natl Acad Sci USA 1967;58:719-26
   PubMed Web of Science ®Google Scholar
• Inglese J, Johnson RL, Simeonov A, et al. High-throughput screening assays for the identification of chemical probes. Nat Chem Biol 2007;3:466-79
   PubMed Web of Science ®Google Scholar
• Liou J, Fivaz M, Inoue T, Meyer T. Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion. Proc Natl Acad Sci USA 2007;104:9301-6
   PubMed Web of Science ®Google Scholar
• Huang GN, Zeng W, Kim JY, et al. STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol 2006;8:1003-10
   PubMed Web of Science ®Google Scholar
• Available from: http://www.isrec.isb-sib.ch/webmarcoil/webmarcoilC1.html
   Google Scholar