The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis

References

• KrausVBBlancoFJEnglundMKarsdalMALohmanderLSCall for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical useOsteoarthritis Cartilage20152381233124125865392
   PubMed Web of Science ®Google Scholar
• AltmanRAschEBlochDDevelopment of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and therapeutic criteria committee of the American Rheumatism AssociationArthritis Rheum1986298103910493741515
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and PreventionOsteoarthritis (OA)2015 Available from: http://www.cdc.gov/arthritis/basics/osteoarthritis.htmAccessed June 18, 2016
   Google Scholar
• CrossMSmithEHoyDThe global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 studyAnn Rheum Dis20147371323133024553908
   PubMed Web of Science ®Google Scholar
• DillonCFRaschEKGuQHirschRPrevalence of knee osteoarthritis in the United States: arthritis data from the Third National Health and Nutrition Examination Survey 1991–1994J Rheumatol200633112271227917013996
   PubMed Web of Science ®Google Scholar
• NueschEDieppePReichenbachSWilliamsSIffSJuniPAll cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort studyBMJ2011342d116521385807
   PubMed Web of Science ®Google Scholar
• VosTFlaxmanADNaghaviMYears lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet201238098592163219623245607
   PubMed Web of Science ®Google Scholar
• RuizDJrKoenigLDallTMThe direct and indirect costs to society of treatment for end-stage knee osteoarthritisJ Bone Joint Surg Am201395161473148023965697
   PubMed Web of Science ®Google Scholar
• BenitoMJVealeDJFitzGeraldOvan den BergWBBresnihanBSynovial tissue inflammation in early and late osteoarthritisAnn Rheum Dis20056491263126715731292
   PubMed Web of Science ®Google Scholar
• SohnDHSokoloveJSharpeOPlasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4Arthritis Res Ther2012141R722225630
   PubMed Web of Science ®Google Scholar
• SokoloveJLepusCMRole of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretationsTher Adv Musculoskelet Dis201352779423641259
   PubMedGoogle Scholar
• BlancoFJRegoIRuiz-RomeroCThe role of mitochondria in osteoarthritisNat Rev Rheumatol20117316116921200395
   PubMed Web of Science ®Google Scholar
• HochbergMCAltmanRDAprilKTAmerican College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and kneeArthritis Care Res (Hoboken)201264446547422563589
   PubMed Web of Science ®Google Scholar
• NelsonAEAllenKDGolightlyYMGoodeAPJordanJMA systematic review of recommendations and guidelines for the management of osteoarthritis: the chronic osteoarthritis management initiative of the U.S. bone and joint initiativeSemin Arthritis Rheum201443670171224387819
   PubMed Web of Science ®Google Scholar
• ZhangWMoskowitzRWNukiGOARSI recommendations for the management of hip and knee osteoarthritis, part II: OARSI evidence-based, expert consensus guidelinesOsteoarthritis Cartilage200816213716218279766
   PubMed Web of Science ®Google Scholar
• ZhangWNukiGMoskowitzRWOARSI recommendations for the management of hip and knee osteoarthritis: part III: changes in evidence following systematic cumulative update of research published through January 2009Osteoarthritis Cartilage201018447649920170770
   PubMed Web of Science ®Google Scholar
• ZhangWMoskowitzRWNukiGOARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidenceOsteoarthritis Cartilage2007159981100017719803
   PubMed Web of Science ®Google Scholar
• Varas-LorenzoCRiera-GuardiaNCalingaertBMyocardial infarction and individual nonsteroidal anti-inflammatory drugs meta-analysis of observational studiesPharmacoepidemiol Drug Saf201322655957023616423
   PubMed Web of Science ®Google Scholar
• SkouSTRoosEMLaursenMBA randomized, controlled trial of total knee replacementN Engl J Med2015373171597160626488691
   PubMed Web of Science ®Google Scholar
• PrasadSGuptaSCTyagiAKAggarwalBBCurcumin, a component of golden spice: from bedside to bench and backBiotechnol Adv20143261053106424793420
   PubMed Web of Science ®Google Scholar
• PariLTewasDEckelJRole of curcumin in health and diseaseArch Physiol Biochem2008114212714918484280
   PubMedGoogle Scholar
• BuhrmannCMobasheriABuschFCurcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathwayJ Biol Chem201128632285562856621669872
   PubMed Web of Science ®Google Scholar
• FuXYYangMFCaoMZStrategy to suppress oxidative damage-induced neurotoxicity in PC12 cells by curcumin: the role of ROS-mediated DNA damage and the MAPK and AKT pathwaysMol Neurobiol201653136937825432891
   PubMed Web of Science ®Google Scholar
• WuJLiQWangXNeuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathwayPLoS One201383e5984323555802
   PubMed Web of Science ®Google Scholar
• CuiQLiXZhuHCurcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathwayMol Med Rep20161321381138826648392
   PubMed Web of Science ®Google Scholar
• AkTGulcinIAntioxidant and radical scavenging properties of curcuminChem Biol Interact20081741273718547552
   PubMed Web of Science ®Google Scholar
• PanahiYSahebkarAParvinSSaadatAA randomized controlled trial on the anti-inflammatory effects of curcumin in patients with chronic sulphur mustard-induced cutaneous complicationsAnn Clin Biochem201249Pt 658058823038702
   PubMedGoogle Scholar
• PanahiYSaadatABeiraghdarFSahebkarAAdjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors: a randomized double-blind placebo-controlled trialPhytother Res201428101461146724648302
   PubMed Web of Science ®Google Scholar
• SinghAKVinayakMCurcumin attenuates CFA induced thermal hyperalgesia by modulation of antioxidant enzymes and down regulation of TNF-alpha, IL-1beta and IL-6Neurochem Res201540346347225479948
   PubMed Web of Science ®Google Scholar
• XuDHuLSuCTetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcuminToxicol Appl Pharmacol2014280230531325123790
   PubMed Web of Science ®Google Scholar
• MoonDOKimMOChoiYHParkYMKimGYCurcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse modelInt Immunopharmacol201010560561020188213
   PubMed Web of Science ®Google Scholar
• BadriaFAEl-FarahatyTShabanaAAHawasSAEl-BatotyMFBoswellia–curcumin preparation for treating knee osteoarthritis: a clinical evaluationAltern Complement Ther200286341348
   Google Scholar
• NakagawaYMukaiSYamadaSShort-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective studyJ Orthop Sci201419693393925308211
   PubMed Web of Science ®Google Scholar
• PanahiYAlishiriGHParvinSSahebkarAMitigation of systemic oxidative stress by curcuminoids in osteoarthritis: results of a randomized controlled trialJ Diet Suppl201613220922025688638
   PubMedGoogle Scholar
• PanahiYRahimniaARSharafiMAlishiriGSaburiASahebkarACurcuminoid treatment for knee osteoarthritis: a randomized double-blind placebo-controlled trialPhytother Res201428111625163124853120
   PubMed Web of Science ®Google Scholar
• RahimniaARPanahiYAlishiriGSharafiMSahebkarAImpact of supplementation with curcuminoids on systemic inflammation in patients with knee osteoarthritis: findings from a randomized double-blind placebo-controlled trialDrug Res (Stuttg)2015651052152525050518
   PubMed Web of Science ®Google Scholar
• KuptniratsaikulVDajprathamPTaechaarpornkulWEfficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter studyClin Interv Aging2014945145824672232
   PubMed Web of Science ®Google Scholar
• KuptniratsaikulVThanakhumtornSChinswangwatanakulPWattanamongkonsilLThamlikitkulVEfficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritisJ Altern Complement Med200915889189719678780
   PubMed Web of Science ®Google Scholar
• KizhakkedathRClinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritisMol Med Rep2013851542154824002213
   PubMed Web of Science ®Google Scholar
• KertiaNAsdieAHRochmahWMarsetyawanAbility of curcuminoid compared to diclofenac sodium in reducing the secretion of cycloxygenase-2 enzyme by synovial fluid’s monocytes of patients with osteoarthritisActa Med Indones201244210511322745140
   PubMedGoogle Scholar
• BelcaroGCesaroneMRDugallMEfficacy and safety of Meriva(R), a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patientsAltern Med Rev201015433734421194249
   PubMedGoogle Scholar
• BelcaroGCesaroneMRDugallMProduct-evaluation registry of Meriva(R), a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritisPanminerva Med2010522 Suppl 1556220657536
   PubMed Web of Science ®Google Scholar
• BelcaroGDugallMLuzziRMeriva(R)+Glucosamine versus Chondroitin + Glucosamine in patients with knee osteoarthritis: an observational studyEur Rev Med Pharmacol Sci201418243959396325555891
   PubMed Web of Science ®Google Scholar
• MadhuKChandaKSajiMJSafety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trialInflammopharmacology201321212913623242572
   PubMed Web of Science ®Google Scholar
• AppelboomTMaesNAlbertAA new curcuma extract (flexofytol(R)) in osteoarthritis: results from a belgian real-life experienceOpen Rheumatol J20148778125352926
   PubMedGoogle Scholar
• HenrotinYGharbiMDierckxsensYDecrease of a specific biomarker of collagen degradation in osteoarthritis, Coll2-1, by treatment with highly bioavailable curcumin during an exploratory clinical trialBMC Complement Altern Med20141415924886572
   PubMed Web of Science ®Google Scholar
• KulkarniRRPatkiPSJogVPGandageSGPatwardhanBTreatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over studyJ Ethnopharmacol1991331–291951943180
   PubMed Web of Science ®Google Scholar
• YangKYLinLCTsengTYWangSCTsaiTHOral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MSJ Chromatogr B Analyt Technol Biomed Life Sci20078531–2183189
   PubMed Web of Science ®Google Scholar
• LiuWZhaiYHengXOral bioavailability of curcumin: problems and advancementsJ Drug Target201624869470226942997
   PubMed Web of Science ®Google Scholar
• MarczyloTHVerschoyleRDCookeDNMorazzoniPStewardWPGescherAJComparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholineCancer Chemother Pharmacol200760217117717051370
   PubMed Web of Science ®Google Scholar
• SunagawaYHiranoSKatanasakaYColloidal submicron-particle curcumin exhibits high absorption efficiency-a double-blind, 3-way crossover studyJ Nutr Sci Vitaminol (Tokyo)2015611374425994138
   PubMed Web of Science ®Google Scholar
• MorimotoTSunagawaYKatanasakaYDrinkable preparation of Theracurmin exhibits high absorption efficiency – a single-dose, double-blind, 4-way crossover studyBiol Pharm Bull201336111708171424189415
   PubMed Web of Science ®Google Scholar
• KanaiMOtsukaYOtsukaKA phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patientsCancer Chemother Pharmacol20137161521153023543271
   PubMed Web of Science ®Google Scholar
• ReenRKJamwalDSTanejaSCImpairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperineBiochem Pharmacol19934622292388347144
   PubMed Web of Science ®Google Scholar
• ShobaGJoyDJosephTMajeedMRajendranRSrinivasPSInfluence of piperine on the pharmacokinetics of curcumin in animals and human volunteersPlanta Med19986443533569619120
   PubMed Web of Science ®Google Scholar
• ComblainFSanchezCLesponneIBalligandMSerisierSHenrotinYCurcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator’s synthesis by normal bovine and osteoarthritic human chondrocytes in monolayerPLoS One2015103e012165425799427
   PubMed Web of Science ®Google Scholar
• CsakiCMobasheriAShakibaeiMSynergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosisArthritis Res Ther2009116R16519889203
   PubMed Web of Science ®Google Scholar
• Schulze-TanzilGMobasheriASendzikJJohnTShakibaeiMEffects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytesAnn N Y Acad Sci2004103057858615659840
   PubMed Web of Science ®Google Scholar
• ShakibaeiMJohnTSchulze-TanzilGLehmannIMobasheriASuppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: implications for the treatment of osteoarthritisBiochem Pharmacol20077391434144517291458
   PubMed Web of Science ®Google Scholar
• ShakibaeiMMobasheriABuhrmannCCurcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitroGenes Nutr20116217117921484156
   PubMed Web of Science ®Google Scholar
• ShakibaeiMSchulze-TanzilGJohnTMobasheriACurcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological studyAnn Anat20051875–648749716320828
   PubMed Web of Science ®Google Scholar
• BuhrmannCMobasheriAMatisUShakibaeiMCurcumin mediated suppression of nuclear factor-kappaB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironmentArthritis Res Ther2010124R12720594343
   PubMed Web of Science ®Google Scholar
• ClutterbuckALAllawayDHarrisPMobasheriACurcumin reduces prostaglandin E2, matrix metalloproteinase-3 and proteoglycan release in the secretome of interleukin 1beta-treated articular cartilageF1000Res2013214724555068
   PubMedGoogle Scholar
• YangQWuSMaoXWangWTaiHInhibition effect of curcumin on TNF-alpha and MMP-13 expression induced by advanced glycation end products in chondrocytesPharmacology2013911–2778523183190
   PubMed Web of Science ®Google Scholar
• ToegelSWuSQPianaCComparison between chondroprotective effects of glucosamine, curcumin, and diacerein in IL-1beta-stimulated C-28/I2 chondrocytesOsteoarthritis Cartilage200816101205121218321735
   PubMed Web of Science ®Google Scholar
• Lev-AriSStrierLKazanovDCurcumin synergistically potentiates the growth-inhibitory and pro-apoptotic effects of celecoxib in osteoarthritis synovial adherent cellsRheumatology (Oxford)200645217117716249246
   PubMed Web of Science ®Google Scholar
• TenBroekEMYunkerLNiesMFBendeleAMRandomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the ratArthritis Res Ther2016182426794830
   PubMed Web of Science ®Google Scholar
• Mathy-HartertMJacquemond-ColletIPriemFSanchezCLambertCHenrotinYCurcumin inhibits pro-inflammatory mediators and metalloproteinase-3 production by chondrocytesInflamm Res2009581289990819579007
   PubMed Web of Science ®Google Scholar
• van DelftMAHuitemaLFTasSWThe contribution of NF-kappaB signalling to immune regulation and toleranceEur J Clin Invest201545552953925735405
   PubMed Web of Science ®Google Scholar