207
Views
30
CrossRef citations to date
0
Altmetric
Review

Antibiotic susceptibility, heteroresistance, and updated treatment strategies in Helicobacter pylori infection

, , &
Pages 2209-2220 | Published online: 28 Jul 2017

References

  • AthertonJCPeekRMThamKTCoverTLBlaserMJClinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pyloriGastroenterology19971121 92 998978347
  • LoganRPHBergDEGenetic diversity of Helicobacter pyloriLancet19963489040 1462 14638942769
  • AndoTMinamiMIshiguroKChanges in biochemical parameters related to atherosclerosis after Helicobacter pylori eradicationAliment Pharmacol Ther200624s4 58 64
  • KanbayMGurGYucelMYlmazUBoyaciogluSDoes eradication of Helicobacter pylori infection help normalize serum lipid and CRP levels?Dig Dis Sci200557 1228 1231
  • GoodmanKJCorreaPThe transmission of Helicobacter pylori: a critical review of the evidenceInt J Epidemiol1995245 875 8778557443
  • EusebiLHZagariRMBazzoliFEpidemiology of Helicobacter pylori infectionHelicobacter201419Suppl 1 1 5
  • FordACAxonATEpidemiology of Helicobacter pylori and public health implicationHelicobacter2010151 1 6
  • GohKLChanWKShiotaSYamaokaYEpidemiology of Helicobacter pylori infection and public health implicationHelicobacter2011161 1 9
  • EverhartJERecent developments in the epidemiology of Helicobacter pyloriGastroenterol Clin North Am2000293 559 57811030073
  • DaneshJEstimating the contribution of Helicobacter pylori to gastric cancerBr J cancer2000837 970 200010970705
  • BisselliRFortiniMMatricardiPMStroffoliniTD’AmelioRIncidence of Helicobacter pylori infection in a cohort of Italian military studentsInfection1999273 187 19110378130
  • FarkheriHBariZArabiMMalekzadehRHelicobacter pylori eradication in west Asia: a reviewWorld J Gastroenterol20142030 10355 1036725132752
  • YangTLiHChenJEpidemiological study on antibiotics resistance among Helicobacter pylori in Taizhou District. Zhejiang, 2010–2013Zhonghua Liu Xing Bing Xue Za Zhi2014356 704 70725174476
  • OderdaGMariettiMPellicanoRDiagnosis and treatment of Helicobacter pylori infection in pediatrics: recommendation for 2014 clinical practiceMinerva Pediatr2015676 517 52426530493
  • GrahamDYFishbachLHelicobacter pylori treatment in the era of increasing antibiotic resistanceGut2010598 1143 115320525969
  • LooVgFalloneCADe SouzaELavalléeJBarkunANIn-vitro susceptibility of Helicobacter pylori to ampicillin, chlarithromycin, metronidazole and omeprazoleJ Antimicrobial Chemother1997406 881 883
  • CheungJMorseALGoodmanKJM1058 Prevalence of Helicobacter pylori and antibiotic resistance in an aboriginal population in Canada’s Arctic: preliminary results from the Aklavik H.pylori ProjectGastrenterology20091365 A341
  • YangJCLinCJWangHLHigh dose dual therapy is superior to standard first line or rescue therapy for Helicobacter pylori infectionClin Gastronterol Hepatol2015135 895 905
  • van ZantenSVDesaiSBestLRescue therapy using a rifabutin based regimen is effective for cure of Helicobacter pylori infectionCan J Gastroenterol2010245 303 30620485704
  • LeeJYKimNKimMSFactors affecting first-line triple therapy of Helicobacter pylori, including CYP2C19 genotype and antibiotic resistanceDig Dis Sci20145596 1235 1243
  • de la ObraPAlarconTDomingoDGarciaJLopez-BreaMHeteroresistance to metronidazole and genetic relationship of Helicobacter pylori clinical isolatesGut2001494 A4
  • YanWHChenJHuHJYuJDHuangXLLiZYPreliminary study on “in vitro” induction of antibiotic resistance in Helicobacter pylori strains isolated from childrenZhonghua Er Ke Za Zhi2007459 708 71118021568
  • ThungIAraminHVavinskayaVReview article: the global emergence of Helicobacter pylori antibiotic resistanceAliment Pharmacol Ther2016434 514 53326694080
  • GerritsMMvan der WoudenEJBaxDARole of the rdxA and frxA genes in oxygen dependent metronidazole resistance of Helicobacter pyloriJ Med Microbiol20045311 1123 112815496391
  • LiLKeYYuCAntibiotic resistance of Helicobacter pylori in Chinese children: a multicenter retrospective study over 7 yearsHelicobacter Epub2017118
  • BouihatNBurucoaCBenkiraneAHelicobacter pylori primary antibiotic resistance in 2015 in Morocco: a phenotypic and genotypic prospective and multicenter studyMicrob Drug Resist Epub20161220
  • ShiotaSReddyRAlsarrajAEl-SeragHBGrahamDYAntibiotic resistance of Helicobacter pylori among male United States veteransClin Gastroenterol Hepatol201513 1616 162425681693
  • Di GiulioMDi CampliEDi BartolomeoSIn vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in central ItalyScand J Gastroenterol2016513 263 26926554617
  • PilottoARassuMLeandroGFranceschiMDi MarioFInterdisciplinary Group for the Study of UlcerPrevalence of Helicobacter pylori resistance to antibiotics in Northeast Italy: a multicentre study. GISU. Interdisciplinary Group for the study of ulcerDig Liver Dis2000329 763 76811215555
  • TorresJCamorlinga-PonceMPerez-PerezGIncreasing multidrug resistance in Helicobacter pylori strains isolated from children and adults in MexicoJ Clin Microbiol2001397 2677 268011427594
  • KatoMYamaokaYKimJJRegional differences in metronidazole resistance and increasing clarithromycin resistance among Helicobacter pylori isolates from JapanAntimicrob Agents Chemother200044 2214 221610898707
  • FalloneCAEpidemiology of the antibiotic resistance of Helicobacter pylori in CanadaCan J Gastroenterol20001410 879 88211111111
  • Perez AldanaLKatoMNakagawaSThe relationship between consumption of antimicrobial agents and the prevalence of primary Helicobacter pylori resistanceHelicobacter200275 306 30912390210
  • MegraudFH. pylori antibiotic resistance: prevalence, importance, and advances in testingGut2004539 1374 138415306603
  • StorskrubbTAroPRonkainenJAntimicrobial susceptibility of Helicobacter pylori strains in a random adult Swedish populationHelicobacter2006114 224 23016882324
  • HorikiNOmataFUemuraMAnnual change of primary resistance to clarithromycin among Helicobacter pylori isolates from 1996 through 2008 in JapanHelicobacter2009145 86 9019751432
  • GaoWChengHHuFThe evolution of Helicobacter pylori antibiotics resistance over 10 years in Beijing, ChinaHelicobacter2010155 460 46621083752
  • ZhangYXZhouLYSongZQZhangJZHeLHDingYPrimary antibiotic resistance of Helicobacter pylori strains isolated from patients with dyspeptic symptoms in Beijing: a prospective serial studyWorld J Gastroenterol2015219 2786 279225759550
  • De FrancescoVGiorgioFHassanCWorldwide H. pylori antibiotic resistance: a systematic reviewJ Gastrointestin Liver Dis2010194 409 41421188333
  • KimJJReddyRLeeMAnalysis of metronidazole, clarithromycin and tetracycline resistance of Helicobacter pylori isolates from KoreaJ Antimicrob Chemother2001474 459 46111266421
  • MituiMPatelALeosNKDoernCDParkJYNovel Helicobacter pylori sequencing test identifies high rate of clarithromycin resistanceJ Pediatr Gastroenterol Nutr2014591 6 925222804
  • QureshiNNGallaherBSchillerNLEvolution of amoxicillin resistance of Helicobacter pylori in vitro: characterization of resistance mechanismsMicrob Drug Resist2014206 509 51624901497
  • Debets-OssenkoppYJHerscheidAJPotRGKuipersEJKustersJGVandenbroucke-GraulsCMPrevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxycillin, tetracycline and trovafloxacin in The NetherlandsJ Antimicrob Chemother1999434 511 51510350380
  • SelgradMTammerILangnerCDifferent antibiotic susceptibility between antrum and corpus of the stomach, a possible reason for treatment failure of Helicobacter pylori infectionWorld J Gastroenterol201420 16245 1625125473179
  • YoonKHParkSWLeeSWKimBJKimJGClarithromycin-based standard triple therapy can still be effective for Helicobacter pylori eradication in some parts of the KoreaJ Korean Med Sci2014299 1240 124625246742
  • GodoyAPRibeiroMLBenvengoYHAnalysis of antimicrobial susceptibility and virulence factors in Helicobacter pylori clinical isolatesBMC Gastroenterol20033 2012911839
  • GerritsMMde ZoeteMRArentsNLKuipersEJKustersJG16S rRNA mutation-mediated tetracycline resistance in Helicobacter pyloriAntimicrob Agents Chemother2002469 2996 300012183259
  • MegraudFCoenenSVersportenAHelicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumptionGut2013621 34 4222580412
  • Cuch BurgosEFornè BarderaMQuintana RieraSLite LiteJGarau AlemanyJEvolution of the sensitivity of 235 strains of Helicobacter pylori from 1995 to 1998 and impact of antibiotic treatmentEnferm Infecc Microbiol Clin2002204 157 16011996701
  • CattoirVNectouxJLascolsCUpdate on fluoroquinolone resistance in Helicobacter pylori: new mutations leading to resistance and first description of a gyrA polymorphism associated with hypersusceptibilityInt J Antimicrob Agents200729 389 39617303392
  • SaracinoIMZulloAHoltonJHigh prevalence of primary antibiotic resistance in Helicobacter pylori isolates in ItalyJ Gastrointestin Liver Dis2012214 363 36523256118
  • CabritaJOleastroMMatosRFeatures and trends in Helicobacter pylori antibiotic resistance in Lisbon area, Portugal (1990–1999)J Antimicrob Chemother2000466 1029 103111102427
  • ChangWLSheuBSChengHCYangYJYangHBWuJJResistance to metronidazole, clarithromycin and levofloxacin of Helicobacter pylori before and after clarithromycin-based therapy in TaiwanJ Gastroenterol Hepatol2009247 1230 123519476562
  • Cuadrado-LavinASalcines-CaviedesJRCarrascosaMFAntimicrobial susceptibility of Helicobacter pylori to six antibiotics currently used in SpainJ Antimicrob Chemother2011671 170 17321965436
  • KimNKimJMKimCHInstitutional difference of antibiotic resistance of Helicobacter pylori strains in KoreaJ Clin Gastroenterol2006408 683 68716940878
  • BiernatMMPoniewierkaEBlaszcukJAntimicrobial susceptibility of Helicobacter pylori isolates from lower Silesia, PolandArch Med Sci2014103 505 50925097581
  • MascellinoMTOlivaADe AngelisMPorowskaBHelicobacter pylori infection: susceptibility to antimicrobials and eradication rate in pluri treated pangastritis patientsIndian J Appl Res201554 30 32
  • AmitranoMSpezzaferroMSaccoFM1087 H. pylori isolates from proximal and distal stomach of patients with H. pylori infection exhibit resistance and sensitivity to the same antibioticGastroenterology20081344 A335
  • IkezawaKKashimuraHKojimaMPretreatment antimicrobial susceptibilities of paired gastric Helicobacter pylori isolates: antrum versus corpusHelicobacter199944 218 22110597389
  • MatteoMJGranadosGOlmosMWonogaACatalanoMHelicobacter pylori amoxicillin heteroresistance due to point mutation in PBP-1A in esogenic isolatesJ Antimicrob Chemoter2008613 474 477
  • Ben MansourKFendriCBattikhHMultiple and mixed Helicobacter pylori infections: comparison of two epidemiological situations in Tunisia and FranceInfect Genet Evol201637 43 4826518911
  • RaymondJLamarqueDKalachNChaussadeSBurucoaCHigh level of antimicrobial resistance in French Helicobacter pylori isolatesHelicobacter2010151 21 27
  • GarciaMRaymondJGarnierMCremniterJBurucoaCDistribution of spontaneous gyrA mutations in 97 fluoroquinolone-resistant Helicobacter pylori isolates collected in FranceAntimicrob Agents Chemother2012561 550 55122064536
  • KaoCYLeeAYHuangAHHeteroresistance of Helicobacter pylori from the same patient prior to antibiotic treatmentInfect Genet Evol201423 196 20224576534
  • OleastroMMenardASantosAReal-time PCR assay for rapid and accurate detection of point mutations conferring resistance to clarithromycin in Helicobacter pyloriJ Clin Microbiol2003411 397 40212517879
  • KimJJKimJGKnownDHMixed-infection of antibiotics susceptible and resistant Helicobacter pylori isolates in a single patient and underestimation of antimicrobial susceptibility testingHelicobacter200383 202 20612752732
  • MascellinoMTPorowskaBNicosiaROlivaABocciaPSeveriCImpact of Helicobacter pylori in unsuccessfully pluritreated patients in a department of infectious disease in RomeMicrobiol Res20102 9 14
  • Van der EndeAvan DoornLJRooijakkersSFellerMTytgatGNJDankertJClarithromycin-susceptible and –resistant Helicobacter pylori isolates with identical randomly amplified polymorphic DNA-PCR genotypes cultured from single gastric biopsy specimens prior to antibiotic therapyJ Clin Microbiol2001397 2648 265111427586
  • NorazahARasinahWZZailiZAminuddinARamelahMAnalysis of PCR-Rapid DNA and antibiotic susceptibility profiles of antrum and corpus of the same isolates of Helicobacter pylori from Malaysian patientsMalays J Pathol2009311 29 3419694311
  • GlockerEBerningMGerritsMMKustersJGKistMReal time PCR screening for 16 S rRna mutations associated with resistance to tetracycline in Helicobacter pyloriAntimicrob Agents Chemoter2005498 3166 3170
  • HeepMKistMStrobelSBeckDLehnNSecondary resistance among 554 isolates of Helicobacter pylori after failure of therapyEur J Clin Microbiol Infect Dis2000197 538 54110968325
  • ChisholmSAOwenRJTeareELSaverymuttuSPCR-based diagnosis of Helicobacter pylori infection and real-time determination of clarithromycin resistance directly from human gastric biopsy samplesJ Clin Microbiol2001394 1217 122011283030
  • LiouJMChenCCChangCYEfficacy of genotypic resistance-guided sequential therapy in the third-line treatment of refractory Helicobacter pylori infection: a multicentre clinical trialJ Antimicrob Chemother2013682 450 45623099849
  • Schabereiter-GurtnerCHirschlAMDragosicsBNovel real-time PCR assay for detection of Helicobacter pylori infection and simultaneous clarithromycin susceptibility testing of stool and biopsy specimensJ Clin Microbiol200442 4512 451815472302
  • MiwaHNagaharaAKurosawaAIs antimicrobial susceptibility testing necessary before second-line treatment for Helicobacter pylori infection?Aliment Pharmacol Ther20031712 1545 155112823158
  • WenzhenYYuminLQuanlinGIs antimicrobial susceptibility testing necessary before first-line treatment for Helicobacter pylori infection? Meta – analysis of randomized controlled trialsIntern Med20104912 1103 110920558925
  • GomollonFSiciliaBDucónsJASierraERevilloMJFerreroMThird line treatment for Helicobacter pylori: a prospective, cultured-guided study in peptic ulcer patientsAliment Pharmacol Ther20001410 1335 133811012479
  • GrahamDYEditorial: avoiding unethical Helicobacter pylori clinical trials: susceptibility-based studies and probiotics as adjuvantsHelicobacter2015205 321 32526123529
  • ZulloAHassanCLorenzettiRWinnSMoriniSA clinical practice viewpoint: to culture or not to culture Helicobacter pylori?Dig Liver Dis2003355 357 36112846409
  • WuJYLiouJMGrahamDYEvidence based recommendations for successful Helicobacter pylori treatmentExpert Rev Gastroenterol Hepatol201481 21 2824410470
  • JenksPJCauses of failure of eradication of Helicobacter pylori. Antibiotic resistance is the major cause and susceptibility testing may helpBMJ20023257354 3 412098709
  • DixonMFGentaRMYardleyJHCorreaPClassification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994Am J Surg Pathol19962010 1161 11818827022
  • GisbertJPGonzalezLCalvetXProton pump inhibitor, clarithromycin and either amoxicillin or nitroimidazole: a meta-analysis of eradication of Helicobacter pyloriAliment Pharmacol Ther20001410 1319 132811012477
  • FalloneCAChibaNvan ZantenSVThe Toronto consensus for treatment of Helicobacter pylori infection in adultsGastroenterology20161511 51 6927102658
  • LaineLHuntREl-ZimaityHNguyenBOsatoMSpénardJBismuth-based quadruple therapy using a single capsule of bismuth biskalcitrate, metronidazole and tetracycline given with omeprazole versus omeprazole, amoxicillin, and clarithromycin for eradication of Helicobacter pylori in duodenal ulcer patients: randomized, multicenter North American trialAm J Gastroenterol2003983 562 56712650788
  • VeneritoMKriegerTEcherTLeandroGMalfertheinerPMeta-analysis of bismuth quadruple therapy versus clarithromycin triple therapy for empiric primary treatment of Helicobacter pylori infectionDigestion2013881 33 4523880479
  • MatsumotoHShiotaniAKatsumataRHelicobacter pylori eradication with proton pump inhibitors or potassium-competitive acid blockers: the effect of clarithromycin resistanceDig Dis Sci20166111 3215 322027659671
  • ZulloAGattaLDe FrancescoVHigh rate of Helicobacter pylori eradication with sequential therapy in elderly patients with peptic ulcer: a Prospective Controlled StudyAliment Pharmacoy Ther20052112 1419 1424
  • WuDCHsuPIWuJYSequential and concomitant therapy with four drugs is equally effective for eradication of H. pylori infectionClin Gastroenterol Hepatol201081 36 4119804842
  • EssaASKramerJRGrahamDYTreiberGMeta-analysis: four-drug, three-antibiotic, non-bismuth containing “concomitant therapy” versus triple therapy for Helicobacter pylori eradicationHelicobacter2009142 109 11819298338
  • TursiADi MarioFFranceschiMNew bismuth-containing quadruple therapy in patients infected with Helicobacter pylori: a first Italian experience in clinical practiceHelicobacter Epub2017126
  • DelchierJCMalfertheinerPThieroff-EkerdtRUse of combination formulation of bismuth,metronidazole and tetracycline with omeprazole as a rescue therapy for eradication of Helicobacter pyloriAliment Pharmacol Ther2014402 171 17724863854
  • LeeYJParkKSOptimal first-line treatment for Helicobacter pylori infection: recent strategiesGastroenterol Res Pract20162016 908658128070184
  • AkazawaYFukudaDFukudaYVonoprazan-based therapy for Helicobacter pylori eradication: experience and clinical evidenceTherap Adv Gastroenterol201696 845 852
  • MurakamiKSakuraiYShiinoMFunaoNNishimuraAAsakaMVonoprazan a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomized, double-blind studyGut2016659 1439 144626935876
  • SuzukiSGotodaTKusanoCIwatsukaKMoriyamaMThe efficacy and tolerability of a triple therapy containing a potassium-competitive acid blocker compared with a 7-day, PPI-based low-dose clarithromycin triple therapyAm J Gastroenterol20161117 949 95627185079
  • NodaHNoguchiSYoshimineTA novel potassium-competitive acid blocker improves the efficacy of clarithromycin-containing 7-day triple therapy against Helicobacter pyloriJ Gastrointestin Liver Dis2016253 283 28827689190
  • AyalaGEscobedo-HinojosaWIde la Cruz-HerreraCFHerreraCRomerIExploring alternative treatment for Helicobacter pylori infectionWorld J Gastroenterol2014206 1450 146924587621
  • RuggieroPUse of probiotics in the fight against Helicobacter pyloriWorld J Gastrointest Pathophysiol201454 384 39125400981
  • GopalRJeongESeoCHParkYRole of antimicrobical peptides expressed by host cells upon infection by Helicobacter pyloriProtein Pept Lett20142110 1057 106425001211