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Review

Dasatinib for the treatment of chronic myeloid leukemia: patient selection and special considerations

, &
Pages 3355-3361 | Published online: 13 Oct 2016

References

  • GugliottaGCastagnettiFApolinariMFirst-line treatment of newly diagnosed elderly patients with chronic myeloid leukemia: current and emerging strategiesDrugs201474662764324711014
  • JabbourEKantarjianHChronic myeloid leukemia: 2014 update on diagnosis, monitoring, and managementAm J Hematol201489554755624729196
  • ChenRChenBThe role of dasatinib in the management of chronic myeloid leukemiaDrug Des Devel Ther20159773779
  • BixbyDTalpazMSeeking the causes and solutions to imatinib-resistance in chronic myeloid leukemiaLeukemia201125172221102425
  • BaccaraniMDeiningerMWRostiGEuropean LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013Blood2013122687288423803709
  • BakerSJReddyEPTargeted inhibition of kinases in cancer therapyMt Sinai J Med201077657358621105121
  • SchenoneSBrulloCMusumeciFBottaMNovel dual Src/Abl inhibitors for hematologic and solid malignanciesExpert Opin Investig Drugs2010198931945
  • HaoualaAWidmerNDuchosalMAMontemurroMBuclinTDecosterdLADrug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinibBlood20111178e75e8720810928
  • LiuFLangLWJiangJLuHJWangJMWangSCSynthesis and biopharmaceutical studies of JLTN as potential dasatinib prodrugChem Pharm Bull (Tokyo)201361887788123676628
  • CondorelliFGenazzaniAADasatinib: is it all in the dose?BioDrugs201024315716320222756
  • McFarlandKLWetzsteinGAChronic myeloid leukemia therapy: focus on second-generation tyrosine kinase inhibitorsCancer Control200916213214019337199
  • SteinBSmithBDTreatment options for patients with chronic myeloid leukemia who are resistant to or unable to tolerate imatinibClin Ther201032580482020685492
  • JabbourEDeiningerMHochhausAManagement of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemiaLeukemia201125220121020861918
  • National Comprehensive Cancer NetworkChronic Myeloid Leukemia (Version 1.2016) Available from: http://www.nccn.org/professionals/physician_gls/pdf/cml.pdfAccessed February 2, 2016
  • ShahNPKimDWKantarjianHPotent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinibHaematologica201095223224020139391
  • ReaDVellengaEJunghanssCSix-year follow-up of patients with imatinib-resistant or imatinib-intolerant chronic phase chronic myeloid leukemia receiving dasatinibHaematologica201297Suppl 1199
  • KantarjianHShahNPHochhausADasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemiaN Engl J Med2010362242260227020525995
  • KantarjianHMShahNPCortesJEDasatinib or imatinib in newly diagnosed chronic phase chronic myeloid leukemia: 2-year follow up from a randomized phase 3 trial (DASISION)Blood201211951123112922160483
  • RadichJPKopeckyKJAppelbaumFRA randomized trial of dasatinib 100 mg versus imatinib 400 mg in newly diagnosed chronic phase chronic myeloid leukemiaBlood2012120193898390522915637
  • Hjorth-HansenHStenkeLSöderlundSNordic CML Study GroupDasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006)Eur J Haematol201594324325025082346
  • LarsonRAIs there a best TKI for chronic phase CML?Blood2015126212370237526585806
  • KeskinDEskazanAEThe treatment of chronic myeloid leukaemia (CML) in the era of tyrosine kinase inhibitors – what is new in the battle of CML?Eur Oncol Haematol20151113031
  • CarneiroBAKaplanJBGilesFJTyrosine kinase inhibitor therapy in chronic myeloid leukemia: update on key adverse eventsExpert Rev Hematol20158445747925938861
  • GugliottaGCastagnettiFFogliMImpact of comorbidities on the treatment of chronic myeloid leukemia with tyrosine-kinase inhibitorsExpert Rev Hematol20136556357424083631
  • SoveriniSHochhausANicoliniFEBCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNetBlood201111851208121521562040
  • EskazanAESoysalTErbilginYOzbekUFerhanogluBChronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation are resistant to dasatinib: is that true for all the patients?Leuk Res2011359e145e14621605905
  • EşkazanAESoysalTDasatinib may override F317L BCR-ABL kinase domain mutation in patients with chronic myeloid leukemiaTurk J Haematol201330221121324385789
  • TiribelliMLatagliataRLucianoLImpact of BCR-ABL mutations on response to dasatinib after imatinib failure in elderly patients with chronic-phase chronic myeloid leukemiaAnn Hematol201392217918323053188
  • Pinilla-IbarzJCortesJMauroMJIntolerance to tyrosine kinase inhibitors in chronic myeloid leukemia: definitions and clinical implicationsCancer2011117468869720922786
  • HochhausABaccaraniMDeiningerMDasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinibLeukemia20082261200120618401416
  • KantarjianHPasquiniRLévyVDasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600 milligrams daily: two-year follow-up of a randomized phase 2 study (START-R)Cancer2009115184136414719536906
  • ShahNPKantarjianHMKimDWIntermittant target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and -intolerant chronic-phase chronic myeloid leukemiaJ Clin Oncol200826193204321218541900
  • ValentPHadzijusufovicESchernthanerGHWolfDReaDle CoutrePVascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitorsBlood2015125690190625525119
  • O’HareTWaltersDKStoffregenEPIn vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutantsCancer Res200565114500450515930265
  • Quintas-CardamaAKantarjianHO’BrienSPleural effusion in patients with chronic myelogenous leukemia treated with dasatinib after imatinib failureJ Clin Oncol200725253908391417761974
  • PorkkaKKhouryHJPaquetteRLMatloubYSinhaRCortesJEDasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusionCancer2010116237738619924787
  • EskazanAEEyiceDKurtEAChronic myeloid leukemia patients who develop grade I/II pleural effusion under second-line dasatinib have better responses and outcomes than patients without pleural effusionLeuk Res201438778178724832371
  • EskazanAESoysalTOngorenSGulturkEFerhanogluBAydinYPleural and pericardial effusions in chronic myeloid leukemia patients receiving low-dose dasatinib therapyHaematologica2011963e1521357709
  • Quintás-CardamaAKantarjianHCortesJNilotinib-associated vascular eventsClin Lymphoma Myeloma Leuk201212533734022633167
  • AichbergerKJHerndlhoferSSchernthanerGHProgressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in CMLAm J Hematol201186753353921538470
  • Gora-TyborJMedrasECalbeckaMReal-life comparison of severe vascular events and other non-hematological complications in patients with chronic myeloid leukemia undergoing second-line nilotinib or dasatinib treatmentLeuk Lymphoma20155682309231425563556
  • DouxfilsJHaguetHMullierFAssociation between BCR-ABL tyrosine kinase inhibitors for chronic myeloid leukemia and cardiovascular events, major molecular response, and overall survival: a systematic review and meta-analysisJAMA Oncol Epub24201610.1001/jamaoncol.2015.5932
  • DahlénTEdgrenGLambeMSwedish CML Group and the Swedish CML Register GroupCardiovascular events associated with use of tyrosine kinase inhibitors in chronic myeloid leukemia: a population-based Cohort studyAnn Intern Med Epub614201610.7326/M15-2306
  • ShahNPWallisNFarberHWClinical features of pulmonary arterial hypertension in patients receiving dasatinibAm J Hematol201590111060106426284693
  • Ozgur YurttasNSadriSKeskinDReal-life data and a single center experience on dasatinib-induced pulmonary arterial hypertension in patients with Philadelphia chromosome-positive leukemiasBlood2015126234037
  • PeacockAJMurphyNFMcMurrayJJCaballeroLStewartSAn epidemiological study of pulmonary arterial hypertensionEur Respir J200730110410917360728
  • GuignabertCMontaniDKey roles of Src family tyrosine kinases in the integrity of the pulmonary vascular bedEur Respir J20134113423277514
  • KimDHKamel-ReidSChangHNatural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemiaHaematologica200994113513919066329
  • MustjokiSEkblomMArstilaTPClonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapyLeukemia20092381398140519295545
  • NagataYOhashiKFukudaSKamataNAkiyamaHSakamakiHClinical features of dasatinib-induced large granular lymphocytosis and pleural effusionInt J Hematol201091579980720405252
  • PaydasSDasatinib, large granular lymphocytosis, and pleural effusion: useful or adverse effect?Crit Rev Oncol Hematol201489224224724210599
  • QiuZYXuWLiJYLarge granular lymphocytosis during dasatinib therapyCancer Biol Ther201415324725524352048
  • TanakaHNakashimaSUsudaMRapid and sustained increase of large granular lymphocytes and rare cytomegalovirus reactivation during dasatinib treatment in chronic myelogenous leukemia patientsInt J Hematol201296330831922767140
  • KreutzmanAJaatinenTGrecoDKiller-cell immunoglobulin-like receptor gene profile predicts good molecular response to dasatinib therapy in chronic myeloid leukemiaExp Hematol20124011906913.e122842045
  • RouxCNicoliniFEReaDReversible lymph node follicular hyperplasia associated with dasatinib treatment of chronic myeloid leukemia in chronic phaseBlood2013122173082308424159167
  • OzawaMGEwaltMDGratzingerDDasatinib-related follicular hyperplasia: an underrecognized entity with characteristic morphologyAm J Surg Pathol201539101363136926360368
  • Quintás-CardamaAKantarjianHRavandiFBleeding diathesis in patients with chronic myelogenous leukemia receiving dasatinib therapyCancer2009115112482249019280591
  • Quintás-CardamaAHanXKantarjianHCortesJTyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemiaBlood2009114226126319414863
  • EskazanAEHatemiİÖngören AydınSArMCSoysalTAcute colitis presenting with hematochezia in a patient with chronic myeloid leukemia during dasatinib therapyTurk J Gastroenterol201425Suppl 1233
  • ErkutMErkutNErsozSArslanMSonmezMA case of acute colitis with severe rectal bleeding in a patient with chronic myeloid leukemia after dasatinib useActa Haematol2010123420520620375493