105
Views
6
CrossRef citations to date
0
Altmetric
Original Research

Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde

, , , , , & show all
Pages 141-153 | Published online: 05 Jan 2016

References

  • BruixJShermanMLlovetJMEASL Panel of Experts on HCCClinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European association for the study of the liverJ Hepatol20013542143011592607
  • HwaJSJinYCLeeYS2-methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 inductionJ Ethnopharmacol201213960561522179023
  • DukeJADukeP-AKduCellierJLDuke’s Handbook of Medicinal Plants of the BibleBoca Raton, London, New YorkCRC Press2008
  • ArtandiSEDePinhoRATelomeres and telomerase in cancerCarcinogenesis20103191819887512
  • AleoEHendersonCJFontaniniASolazzoBBrancoliniCIdentification of new compounds that trigger apoptosome-independent caspase activation and apoptosisCancer Res2006669235924416982768
  • McClendonAKOsheroffNDNA topoisomerase II, genotoxicity, and cancerMutat Res2007623839717681352
  • HeckMMEarnshawWCTopoisomerase II: a specific marker for cell proliferationJ Cell Biol1986103256925813025219
  • NaowaratwattanaWDe-EknamkulWDe MejiaEGPhenolic-containing organic extracts of mulberry (Morus alba L.) leaves inhibit HepG2 hepatoma cells through G2/M phase arrest, induction of apoptosis, and inhibition of topoisomerase IIalpha activityJ Med Food2010131045105620828312
  • BaikarSMalpathakNSecondary metabolites as DNA topoisomerase inhibitors: a new era towards designing of anticancer drugsPharmacogn Rev20104122622228937
  • BandeleOJClawsonSJOsheroffNDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementChem Res Toxicol2008211253126018461976
  • SudanSRupasingheHPFlavonoid-enriched apple fraction AF4 induces cell cycle arrest, DNA topoisomerase II inhibition, and apoptosis in human liver cancer HepG2 cellsNutr Cancer2014661237124625256427
  • RayetBGelinasCAberrant rel/nfkb genes and activity in human cancerOncogene1999186938694710602468
  • VandorosGPKonstantinopoulosPASotiropoulou-BonikouGPPAR-gamma is expressed and NF-kB pathway is activated and correlates positively with COX-2 expression in stromal myofibroblasts surrounding colon adenocarcinomasJ Cancer Res Clin Oncol2006132768416215757
  • HarrisRECyclooxygenase-2 (cox-2) and the inflammogenesis of cancerSubcell Biochem2007429312617612047
  • DarzynkiewiczZDifferential staining of DNA and RNA in intact cells and isolated cell nuclei with acridine orangeMethods Cell Biol1990332852981707487
  • FanCWangWZhaoBZhangSMiaoJChloroquine inhibits cell growth and induces cell death in A549 lung cancer cellsBioorg Med Chem2006143218322216413786
  • OlivePLBanathJPThe comet assay: a method to measure DNA damage in individual cellsNat Protoc20061232917406208
  • ReersMSmileySTMottola-HartshornCChenALinMChenLBMitochondrial membrane potential monitored by JC-1 dyeMethods Enzymol19952604064178592463
  • MartinEJForkertPGEvidence that 1,1-dichloroethylene induces apoptotic cell death in murine liverJ Pharmacol Exp Ther2004310334215028783
  • Har-VardiIMaliRBreietmanMDNA topoisomerases I and II in human mature sperm cells: characterization and unique propertiesHum Reprod2007222183218917656417
  • CherngJMLinHJHungMSLinYRChanMHLinJCInhibition of nuclear factor kappaB is associated with neuroprotective effects of glycyrrhizic acid on glutamate-induced excitotoxicity in primary neuronsEur J Pharmacol2006547102116952351
  • BenotmaneAMHoylaertsMFCollenDBelayewANonisotopic quantitative analysis of protein-DNA interactions at equilibriumAnal Biochem19972501811859245437
  • WhiteKGretherMEAbramsJMYoungLFarrellKStellerHGenetic control of programmed cell death in DrosophilaScience19942646776838171319
  • MpokeSSWolfeJDifferential staining of apoptotic nuclei in living cells: application to macronuclear elimination in tetrahymenaJ Histochem Cytochem1997456756839154154
  • WyllieAHKerrJFCurrieARCell death: the significance of apoptosisInt Rev Cytol1980682513067014501
  • CoverTLPuryearWPerez-PerezGIBlaserMJEffect of urease on HeLa cell vacuolation induced by Helicobacter pylori cytotoxinInfect Immun199159126412702004808
  • PatelHKWillhiteDCPatelRMPlasma membrane cholesterol modulates cellular vacuolation induced by the Helicobacter pylori vacuolating cytotoxinInfect Immun2002704112412312117919
  • PommierYDiversity of DNA topoisomerases I and inhibitorsBiochimie1998802552709615865
  • LiTKLiuLFTumor cell death induced by topoisomerase-targeting drugsAnnu Rev Pharmacol Toxicol200141537711264450
  • PommierYPourquierPUrasakiYWuJLacoGSTopoisomerase I inhibitors: selectivity and cellular resistanceDrug Resist Updat1999230731811504505
  • WillettWCBalancing life-style and genomics research for disease preventionScience200229669569811976443
  • BlockGPattersonBSubarAFruit, vegetables, and cancer prevention: a review of the epidemiological evidenceNutr Cancer1992181291408943
  • ShuklaSMeeranSMKatiyarSKEpigenetic regulation by selected dietary phytochemicals in cancer chemopreventionCancer Lett201435591725236912
  • PriyadarsiniRVNaginiSCancer chemoprevention by dietary phytochemicals: promises and pitfallsCurr Pharm Biotechnol20121312513621466433
  • SurhYJCancer chemoprevention with dietary phytochemicalsNat Rev Cancer2003376878014570043
  • YangCSLandauJMHuangMTNewmarkHLInhibition of carcinogenesis by dietary polyphenolic compoundsAnnu Rev Nutr20012138140611375442
  • WatsonWHCaiJJonesDPDiet and apoptosisAnnu Rev Nutr20002048550510940343
  • MiddletonEJrKandaswamiCTheoharidesTCThe effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancerPharmacol Rev20005267375111121513
  • TanakaSYoonYHFukuiHAntiulcerogenic compounds isolated from Chinese cinnamonPlanta Med1989552452482740458
  • ReddyAMSeoJHRyuSYCinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamo-mum cassiaPlanta Med20047082382715503352
  • MiuraTChibaMKasaiKApple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3Carcinogenesis20082958559317827407
  • LiuJRDongHWChenBQZhaoPLiuRHFresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley ratJ Agric Food Chem20095729730419072049
  • YoonHLiuRHEffect of selected phytochemicals and apple extracts on NF-kappaB activation in human breast cancer MCF-7 cellsJ Agric Food Chem2007553167317317373813
  • ZhengCQQiaoBWangMTaoQMechanisms of apple polyphenols-induced proliferation inhibiting and apoptosis in a metastatic oral adenoid cystic carcinoma cell lineKaohsiung J Med Sci20132923924523639509
  • PopCTimmerJSperandioSSalvesenGSThe apoptosome activates caspase-9 by dimerizationMol Cell20062226927516630894
  • ZouHHenzelWJLiuXLutschgAWangXApaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3Cell1997904054139267021
  • LiPNijhawanDBudihardjoICytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascadeCell1997914794899390557
  • OnoKWangXHanJResistance to tumor necrosis factor-induced cell death mediated by PMCA4 deficiencyMol Cell Biol2001218276828811713265
  • HusainIMohlerJLSeiglerHFBestermanJMElevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapyCancer Res1994545395468275492
  • HsiangYHWuHYLiuLFProliferation-dependent regulation of DNA topoisomerase II in cultured human cellsCancer Res198848323032352835157
  • BaldwinELOsheroffNEtoposide, topoisomerase II and cancerCurr Med Chem Anticancer Agents2005536337216101488
  • El-AwadyRAAliMMSalehEMGhalebFMApoptosis is the most efficient death-pathway in tumor cells after topoisomerase II inhibitionSaudi Med J20082955856418382799
  • DennyWABaguleyBCDual topoisomerase I/II inhibitors in cancer therapyCurr Top Med Chem2003333935312570767
  • YangYZhuJGouHCaoDJiangMHouMClinical significance of Cox-2, survivin and Bcl-2 expression in hepatocellular carcinoma (HCC)Med Oncol20112879680320401641