A novel hydrolysis-resistant lipophilic folate derivative enables stable delivery of targeted liposomes in vivo

References

• ElwoodPCMolecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cellsJ Biol Chem19892642514893149012768245
   PubMed Web of Science ®Google Scholar
• LaceySWSandersJMRothbergKGAndersonRGKamenBAComplementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl-phosphatidylinositolJ Clin Invest19898427157202527252
   PubMed Web of Science ®Google Scholar
• WuMGunningWRatnamMExpression of folate receptor type alpha in relation to cell type, malignancy, and differentiation in ovary, uterus, and cervixCancer Epidemiol Biomarkers Prev19998977578210498396
   PubMed Web of Science ®Google Scholar
• RossJFChaudhuriPKRatnamMDifferential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implicationsCancer1994739243224437513252
   PubMed Web of Science ®Google Scholar
• ParkerNTurkMJWestrickELewisJDLowPSLeamonCPFolate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assayAnal Biochem2005338228429315745749
   PubMed Web of Science ®Google Scholar
• LeamonCPFolate-targeted drug strategies for the treatment of cancerCurr Opin Investig Drugs200891212771286
   PubMedGoogle Scholar
• ZhaoXBLeeRJTumor-selective targeted delivery of genes and antisense oligodeoxyribonucleotides via the folate receptorAdv Drug Deliv Rev20045681193120415094215
   PubMed Web of Science ®Google Scholar
• PanXQZhengXShiGWangHRatnamMLeeRJStrategy for the treatment of acute myelogenous leukemia based on folate receptor beta-targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acidBlood2002100259460212091353
   PubMed Web of Science ®Google Scholar
• WangSLowPSFolate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cellsJ Control Release1998531–339489741912
   PubMed Web of Science ®Google Scholar
• HenneWADoorneweerdDDHilgenbrinkARKularatneSALowPSSynthesis and activity of a folate peptide camptothecin prodrugBioorg Med Chem Lett200616205350535516901694
   PubMed Web of Science ®Google Scholar
• BaeYNishiyamaNKataokaKIn vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartmentsBioconjug Chem20071841131113917488066
   PubMed Web of Science ®Google Scholar
• SanhaiWRSakamotoJHCanadyRFerrariMSeven challenges for nanomedicineNat Nanotechnol20083524224418654511
   PubMed Web of Science ®Google Scholar
• RahmanAHusainSRSiddiquiJLiposome-mediated modulation of multidrug resistance in human HL-60 leukemia cellsJ Natl Cancer Inst19928424190919151361008
   PubMedGoogle Scholar
• GabizonAShmeedaHHorowitzATZalipskySTumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugatesAdv Drug Deliv Rev20045681177119215094214
   PubMed Web of Science ®Google Scholar
• PerezATDomenechGHFrankelCVogelCLPegylated liposomal doxorubicin (Doxil) for metastatic breast cancer: the Cancer Research Network, Inc., experienceCancer Invest200220Suppl 2222912442346
   PubMedGoogle Scholar
• TheodoulouMHudisCCardiac profiles of liposomal anthracyclines: greater cardiac safety versus conventional doxorubicin?Cancer2004100102052206315139046
   PubMed Web of Science ®Google Scholar
• SafraTCardiac safety of liposomal anthracyclinesOncologist20038Suppl 2172413679592
   PubMed Web of Science ®Google Scholar
• BatistGCardiac safety of liposomal anthracyclinesCardiovasc Toxicol200772727417652807
   PubMed Web of Science ®Google Scholar
• LeamonCPCooperSRHardeeGEHardee, Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: evaluation in vitro and in vivoBioconjug Chem200314473874712862426
   PubMed Web of Science ®Google Scholar
• GabizonAHorowitzATGorenDTzemachDShmeedaHZalipskySIn vivo fate of folate-targeted polyethylene-glycol liposomes in tumor-bearing miceClin Cancer Res20039176551655914695160
   PubMed Web of Science ®Google Scholar
• LeeRJLowPSFolate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitroBiochim Biophys Acta1995123321341447865538
   PubMed Web of Science ®Google Scholar
• GabizonAHorowitzATGorenDTargeting folate receptor with folate linked to extremities of poly(ethylene glycol)-grafted liposomes: in vitro studiesBioconjug Chem199910228929810077479
   PubMed Web of Science ®Google Scholar
• XiangGWuJLuYLiuZLeeRJSynthesis and evaluation of a novel ligand for folate-mediated targeting liposomesInt J Pharm2008356293618258394
   PubMed Web of Science ®Google Scholar
• LiuYXuSTengLSynthesis and evaluation of a novel lipophilic folate receptor targeting ligandAnticancer Res20113151521152521617205
   PubMed Web of Science ®Google Scholar
• WuJLiuQLeeRJA folate receptor-targeted liposomal formulation for paclitaxelInt J Pharm20063161–214815316564654
   PubMedGoogle Scholar
• MasudaTAkitaHNishioTDevelopment of lipid particles targeted via sugar-lipid conjugates as novel nuclear gene delivery systemBiomaterials200829670972318001828
   PubMed Web of Science ®Google Scholar
• HaranGCohenRBarLKBarenholzYTransmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak basesBiochim Biophys Acta1993115122012158373796
   PubMed Web of Science ®Google Scholar
• StevensPJSekidoMLeeRJA folate receptor-targeted lipid nanoparticle formulation for a lipophilic paclitaxel prodrugPharm Res200421122153215715648245
   PubMed Web of Science ®Google Scholar
• HattoriYMaitaniYFolate-linked lipid-based nanoparticle for targeted gene deliveryCurr Drug Deliv20052324325216305426
   PubMedGoogle Scholar
• ChenCHanDCaiCTangXAn overview of liposome lyophilization and its future potentialJ Control Release2010142329931119874861
   PubMed Web of Science ®Google Scholar
• ZhaoXBMuthusamyNByrdJCLeeRJCholesterol as a bilayer anchor for PEGylation and targeting ligand in folate-receptor-targeted liposomesJ Pharm Sci20079692424243517588260
   PubMed Web of Science ®Google Scholar
• WeitmanSDLarkRHConeyLRDistribution of the folate receptor GP38 in normal and malignant cell lines and tissuesCancer Res19925212339634011596899
   PubMed Web of Science ®Google Scholar
• MullerCForrerFSchibliRKrenningEPde JongMSPECT study of folate receptor-positive malignant and normal tissues in mice using a novel 99mTc-radiofolateJ Nucl Med200849231031718199624
   PubMed Web of Science ®Google Scholar
• ChangHIYehMKClinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacyInt J Nanomedicine20127496022275822
   PubMed Web of Science ®Google Scholar
• ChaoTCWangWSYenCCChiouTJLiuJHChenPMA dose-escalating pilot study of sterically stabilized, pegylated liposomal doxorubicin (Lipo-Dox) in patients with metastatic breast cancerCancer Invest200321683784714735687
   PubMed Web of Science ®Google Scholar
• LyassOUzielyBBen-YosefRCorrelation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil) in metastatic breast carcinomaCancer20008951037104710964334
   PubMed Web of Science ®Google Scholar
• DromiSFrenkelVLukAPulsed-high intensity focused ultrasound and low temperature-sensitive liposomes for enhanced targeted drug delivery and antitumor effectClin Cancer Res20071392722272717473205
   PubMed Web of Science ®Google Scholar
• LuYWuJGonitMRole of formulation composition in folate receptor-targeted liposomal doxorubicin delivery to acute myelogenous leukemia cellsMol Pharm20074570771217708654
   PubMed Web of Science ®Google Scholar
• ZhaiGWuJXiangGPreparation, characterization and pharmacokinetics of folate receptor-targeted liposomes for docetaxel deliveryJ Nanosci Nanotechnol2009932155216119435095
   PubMed Web of Science ®Google Scholar
• ZhangQXiangGZhangYIncrease of doxorubicin sensitivity for folate receptor positive cells when given as the prodrug N-(phenylacetyl) doxorubicin in combination with folate-conjugated PGAJ Pharm Sci200695102266227516883559
   PubMed Web of Science ®Google Scholar
• QuXYangCZhangKIn vitro evaluation of a Folate-bovine serum albumin-doxorubicin conjugateJ Drug Target201018535136120001219
   PubMed Web of Science ®Google Scholar
• WhiteSCLoriganPMargisonGPPhase II study of SPI-77 (sterically stabilised liposomal cisplatin) in advanced non-small-cell lung cancerBr J Cancer200695782282816969346
   PubMed Web of Science ®Google Scholar
• BooserDJEstevaFJRiveraEPhase II study of liposomal annamycin in the treatment of doxorubicin-resistant breast cancerCancer Chemother Pharmacol20025016812111105
   PubMed Web of Science ®Google Scholar
• GabizonAShmeedaHBarenholzYPharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studiesClin Pharmacokinet200342541943612739982
   PubMed Web of Science ®Google Scholar
• GabizonACataneRUzielyBProlonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomesCancer Res19945449879928313389
   PubMed Web of Science ®Google Scholar