Advanced search
Publication Cover
Journal of Asthma and Allergy Volume 14, 2021 - Issue
Submit an article Journal homepage
189
Views
3
CrossRef citations to date
0
Altmetric
Original Research

Omega-5 and Gamma Gliadin are the Major Allergens in Adult-Onset IgE-Mediated Wheat Allergy: Results from Thai Cohort with Oral Food Challenge

Surapon Piboonpocanun1 Institute of Molecular Biosciences, Mahidol University, Salaya, Nakhonpathom, ThailandORCID Iconhttps://orcid.org/0000-0003-4374-8003View further author information
ORCID Icon,
Torpong Thongngarm2 Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandORCID Iconhttps://orcid.org/0000-0002-3182-4614View further author information
ORCID Icon,
Chamard Wongsa2 Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandORCID Iconhttps://orcid.org/0000-0002-5721-4881View further author information
ORCID Icon,
Punchama Pacharn3 Division of Allergy and Clinical Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandORCID Iconhttps://orcid.org/0000-0002-2507-2057View further author information
ORCID Icon,
Onrapak Reamtong4 Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandView further author information
&
Mongkhon Sompornrattanaphan2 Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8419-0873View further author information
ORCID Icon
Pages 907-917 | Published online: 15 Jul 2021

References

  • Tatham AS, Shewry PR. Allergens to wheat and related cereals. Clin Exp Allergy. 2008;38(11):1712–1726.
  • Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, et al. EAACI molecular allergology user’s guide. Pediatr Allergy Immunol. 2016;27(Suppl 23):1–250.
  • Battais F, Richard C, Jacquenet S, Denery-Papini S, Moneret-Vautrin DA. Wheat grain allergies: an update on wheat allergens. Eur Ann Allergy Clin Immunol. 2008;40(3):67–76.
  • Cianferoni A. Wheat allergy: diagnosis and management. J Asthma Allergy. 2016;9:13–25.
  • Ebisawa M, Ito K, Fujisawa T. Committee for Japanese pediatric guideline for food allergy TJSoPA, Clinical Immunology TJSoA. Japanese guidelines for food allergy 2017. Allergol Int. 2017;66(2):248–264.
  • Kivity S. Adult-onset food allergy. Isr Med Assoc J. 2012;14(1):70–72.
  • Scibilia J, Rossi CM, Losappio LM, et al. Wheat food allergy in adults has a favorable prognosis. J Investig Allergol Clin Immunol. 2018.
  • Thongngarm T, Wongsa C, Pacharn P, Piboonpocanun S, Sompornrattanaphan M. Clinical characteristics and proposed wheat-cofactor challenge protocol with a high diagnostic yield in adult-onset IgE-mediated wheat allergy. J Asthma Allergy. 2020;13:355–368.
  • Pravettoni V, Incorvaia C. Diagnosis of exercise-induced anaphylaxis: current insights. J Asthma Allergy. 2016;9:191–198.
  • Christensen MJ, Eller E, Mortz CG, Brockow K, Bindslev-Jensen C. Wheat-dependent cofactor-augmented anaphylaxis: a prospective study of exercise, aspirin, and alcohol efficacy as cofactors. J Allergy Clin Immunol Pract. 2019;7(1):114–121.
  • Brockow K, Kneissl D, Valentini L, et al. Using a gluten oral food challenge protocol to improve diagnosis of wheat-dependent exercise-induced anaphylaxis. J Allergy Clin Immunol. 2015;135(4):977–84 e4.
  • Fukutomi Y, Taniguchi M, Nakamura H, Akiyama K. Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap. Allergy. 2014;69(10):1405–1411.
  • Pastorello EA, Farioli L, Conti A, et al. Wheat IgE-mediated food allergy in European patients: alpha-amylase inhibitors, lipid transfer proteins and low-molecular-weight glutenins. Allergenic molecules recognized by double-blind, placebo-controlled food challenge. Int Arch Allergy Immunol. 2007;144(1):10–22.
  • Srisuwatchari W, Sompornrattanaphan M, Jirapongsananuruk O, Visitsunthorn N, Pacharn P. Exercise-food challenge test in patients with wheat-dependent exercise-induced anaphylaxis. Asian Pac J Allergy Immunol. 2021.
  • Pacharn P, Kumjim S, Tattiyapong P, Jirapongsananuruk O, Piboonpocanun S. Identification of wheat sensitization using an in-house wheat extract in Coca-10% alcohol solution in children with wheat anaphylaxis. Asian Pac J Allergy Immunol. 2016;34(2):153–158.
  • van den Broeck HC, America AH, Smulders MJ, et al. A modified extraction protocol enables detection and quantification of celiac disease-related gluten proteins from wheat. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877(10):975–982.
  • Sampson HA, Munoz-Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol. 2006;117(2):391–397.
  • Le TA, Al Kindi M, Tan JA, et al. The clinical spectrum of omega-5-gliadin allergy. Intern Med J. 2016;46(6):710–716.
  • Hofmann SC, Fischer J, Eriksson C, Bengtsson Gref O, Biedermann T, Jakob T. IgE detection to alpha/beta/gamma-gliadin and its clinical relevance in wheat-dependent exercise-induced anaphylaxis. Allergy. 2012;67(11):1457–1460.
  • Yagami A, Aihara M, Ikezawa Z, et al. Outbreak of immediate-type hydrolyzed wheat protein allergy due to a facial soap in Japan. J Allergy Clin Immunol. 2017;140(3):879–81 e7.
  • Liao L, Zhao M, Ren J, Zhao H, Cui C, Hu X. Effect of acetic acid deamidation-induced modification on functional and nutritional properties and conformation of wheat gluten. J Sci Food Agric. 2010;90(3):409–417.
  • Kroghsbo S, Andersen NB, Rasmussen TF, Jacobsen S, Madsen CB. Acid hydrolysis of wheat gluten induces formation of new epitopes but does not enhance sensitizing capacity by the oral route: a study in “gluten free” Brown Norway rats. PLoS One. 2014;9(9):e107137.
  • Hiragun M, Ishii K, Yanase Y, Hiragun T, Hide M. Remission rate of patients with wheat allergy sensitized to hydrolyzed wheat protein in facial soap. Allergol Int. 2016;65(1):109–111.
  • Sapone A, Bai JC, Ciacci C, et al. Spectrum of gluten-related disorders: consensus on new nomenclature and classification. BMC Med. 2012;10:13.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.