Upregulation of Cartilage Oligomeric Matrix Protein Predicts Poor Prognosis in Urothelial Carcinoma

References

• Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. May 2021;71(3):209–249. doi:10.3322/caac.21660
   Google Scholar
• Hung CF, Yang CK, Ou YC. Urologic cancer in Taiwan. Jpn J Clin Oncol. 2016;46(7):605–609. doi:10.1093/jjco/hyw038
   PubMed Web of Science ®Google Scholar
• Li CC, Chang TH, Wu WJ, et al. Significant predictive factors for prognosis of primary upper urinary tract cancer after radical nephroureterectomy in Taiwanese patients. Eur Urol. 2008;54(5):1127–1134. doi:10.1016/j.eururo.2008.01.054
   PubMed Web of Science ®Google Scholar
• Kirkali Z, Chan T, Manoharan M, et al. Bladder cancer: epidemiology, staging and grading, and diagnosis. Urology. 2005;66(6 Suppl 1):4–34. doi:10.1016/j.urology.2005.07.062
   PubMed Web of Science ®Google Scholar
• Ritch CR, Velasquez MC, Kwon D, et al. Use and validation of the AUA/SUO risk grouping for nonmuscle invasive bladder cancer in a contemporary cohort. J Urol. 2020;203(3):505–511. doi:10.1097/JU.0000000000000593
   PubMed Web of Science ®Google Scholar
• van den Bosch S, Alfred Witjes J. Long-term cancer-specific survival in patients with high-risk, non-muscle-invasive bladder cancer and tumour progression: a systematic review. Eur Urol. 2011;60(3):493–500. doi:10.1016/j.eururo.2011.05.045
   PubMed Web of Science ®Google Scholar
• Briggs MD, Hoffman SM, King LM, et al. Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene. Nat Genet. 1995;10(3):330–336. doi:10.1038/ng0795-330
   PubMed Web of Science ®Google Scholar
• Norman GL, Gatselis NK, Shums Z, et al. Cartilage oligomeric matrix protein: A novel non-invasive marker for assessing cirrhosis and risk of hepatocellular carcinoma. World J Hepatol. Jul 18 2015;7(14):1875–83. doi:10.4254/wjh.v7.i14.1875
   Google Scholar
• Englund E, Bartoschek M, Reitsma B, et al. Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer. Oncogene. 2016;35(43):5585–5596. doi:10.1038/onc.2016.98
   PubMed Web of Science ®Google Scholar
• Liu -T-T, Liu X-S, Zhang M, et al. Cartilage oligomeric matrix protein is a prognostic factor and biomarker of colon cancer and promotes cell proliferation by activating the Akt pathway. J Cancer Res Clin Oncol. 2018;144(6):1049–1063. doi:10.1007/s00432-018-2626-4
   PubMed Web of Science ®Google Scholar
• Nfonsam VN, Jecius HC, Janda J, et al. Cartilage oligomeric matrix protein (COMP) promotes cell proliferation in early-onset colon cancer tumorigenesis. Surg Endosc. 2020;34(9):3992–3998. doi:10.1007/s00464-019-07185-z
   PubMed Web of Science ®Google Scholar
• Oldberg A, Antonsson P, Lindblom K, Heinegard D. COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins. J Biol Chem. 1992;267(31):22346–22350. doi:10.1016/S0021-9258(18)41677-8
   PubMed Web of Science ®Google Scholar
• Farina G, Lemaire R, Korn JH, Widom RL. Cartilage oligomeric matrix protein is overexpressed by scleroderma dermal fibroblasts. Matrix Biol. 2006;25(4):213–222. doi:10.1016/j.matbio.2006.01.007
   PubMed Web of Science ®Google Scholar
• Zachou K, Gabeta S, Shums Z, et al. COMP serum levels: a new non-invasive biomarker of liver fibrosis in patients with chronic viral hepatitis. Eur J Intern Med. 2017;38:83–88. doi:10.1016/j.ejim.2017.01.007
   PubMed Web of Science ®Google Scholar
• Tseng S, Reddi AH, Di Cesare PE. Cartilage Oligomeric Matrix Protein (COMP): a biomarker of arthritis. Biomark Insights. 2009;4:33–44. doi:10.4137/bmi.s645
   PubMedGoogle Scholar
• Englund E, Canesin G, Papadakos KS, et al. Cartilage oligomeric matrix protein promotes prostate cancer progression by enhancing invasion and disrupting intracellular calcium homeostasis. Oncotarget. 2017;8(58):98298–98311. doi:10.18632/oncotarget.21176
   PubMedGoogle Scholar
• Li Q, Wang C, Wang Y, et al. HSCs-derived COMP drives hepatocellular carcinoma progression by activating MEK/ERK and PI3K/AKT signaling pathways. J Exp Clin Cancer Res. 2018;37(1):231. doi:10.1186/s13046-018-0908-y
   PubMed Web of Science ®Google Scholar
• Zhang J, Wang H, Lv C, et al. Cartilage oligomeric matrix protein affects the biological behavior of papillary thyroid carcinoma cells by activating the PI3K/AKT/Bcl-2 pathway. J Cancer. 2021;12(6):1623–1633. doi:10.7150/jca.49144
   PubMed Web of Science ®Google Scholar
• Nfonsam VN, Nfonsam LE, Chen D, et al. COMP gene coexpresses with EMT genes and is associated with poor survival in colon cancer patients. J Surg Res. 2019;233:297–303. doi:10.1016/j.jss.2018.08.021
   PubMed Web of Science ®Google Scholar
• Papadakos KS, Bartoschek M, Rodriguez C, et al. Cartilage oligomeric matrix protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling. Matrix Biol. 2019;81:107–121. doi:10.1016/j.matbio.2018.11.007
   PubMed Web of Science ®Google Scholar
• Verma P, Dalal K. Serum cartilage oligomeric matrix protein (COMP) in knee osteoarthritis: a novel diagnostic and prognostic biomarker. J Orthop Res. 2013;31(7):999–1006. doi:10.1002/jor.22324
   PubMed Web of Science ®Google Scholar
• Pastushenko I, Blanpain C. EMT transition states during tumor progression and metastasis. Trends Cell Biol. 2019;29(3):212–226. doi:10.1016/j.tcb.2018.12.001
   PubMed Web of Science ®Google Scholar
• Jandova J, Xu W, Nfonsam V. Sporadic early-onset colon cancer expresses unique molecular features. J Surg Res. 2016;204(1):251–260. doi:10.1016/j.jss.2016.04.068
   PubMed Web of Science ®Google Scholar
• Barrett T, Suzek TO, Troup DB, et al. NCBI GEO: mining millions of expression profiles–database and tools. Nucleic Acids Res. 2005;33(Database issue):D562–6. doi:10.1093/nar/gki022
   PubMedGoogle Scholar
• Tsai KS, Kao SY, Wang CY, Wang YJ, Wang JP, Hung SC. Type I collagen promotes proliferation and osteogenesis of human mesenchymal stem cells via activation of ERK and Akt pathways. J Biomed Mater Res A. 2010;94(3):673–682. doi:10.1002/jbm.a.32693
   PubMed Web of Science ®Google Scholar
• Halasz K, Kassner A, Morgelin M, Heinegard D. COMP acts as a catalyst in collagen fibrillogenesis. J Biol Chem. 2007;282(43):31166–31173. doi:10.1074/jbc.M705735200
   PubMed Web of Science ®Google Scholar
• Somaiah C, Kumar A, Mawrie D, et al. Collagen promotes higher adhesion, survival and proliferation of mesenchymal stem cells. PLoS One. 2015;10(12):e0145068. doi:10.1371/journal.pone.0145068
   PubMed Web of Science ®Google Scholar
• Senoo H, Hata R. Extracellular matrix regulates cell morphology, proliferation, and tissue formation. Kaibogaku Zasshi. 1994;69(6):719–733.
   PubMedGoogle Scholar
• Metharom P, Berndt MC. COMP: an endogenous thrombin inhibitor. Blood. 2015;126(7):831–832. doi:10.1182/blood-2015-06-650846
   PubMed Web of Science ®Google Scholar
• Liang Y, Fu Y, Qi R, et al. Cartilage oligomeric matrix protein is a natural inhibitor of thrombin. Blood. 2015;126(7):905–914. doi:10.1182/blood-2015-01-621292
   PubMed Web of Science ®Google Scholar
• Kurashina R, Ando K, Inoue M, et al. Platelet-to-lymphocyte ratio predicts the efficacy of pembrolizumab in patients with urothelial carcinoma. Anticancer Res. 2022;42(2):1131–1136. doi:10.21873/anticanres.15576
   PubMed Web of Science ®Google Scholar
• Bao Y, Wang Y, Li X, et al. Prognostic significance of platelet-to-lymphocyte ratio in urothelial carcinoma patients: a meta-analysis. Cancer Cell Int. 2019;19(1). doi:10.1186/s12935-019-1032-6.
   Web of Science ®Google Scholar
• Tanaka N, Kikuchi E, Matsumoto K, et al. Prognostic value of plasma fibrinogen levels in patients with localized upper tract urothelial carcinoma. BJU Int. 2013;111(6):857–864. doi:10.1111/j.1464-410X.2012.11353.x
   PubMed Web of Science ®Google Scholar
• Peir-In L, Hong-Yue L, Ti-Chun C, et al. Upregulation of dihydropyrimidinase-like 3 protein predicts poor prognosis in urothelial carcinoma. Onco Targets Ther. 2022;9:1059.
   Google Scholar