32
Views
0
CrossRef citations to date
0
Altmetric
Priority Paper Evaluation

Trem2 Variants and Alzheimer‘s Disease

&
Pages 407-410 | Published online: 05 Jul 2013

References

  • Bouchon A , DietrichJ, ColonnaM. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J. Immunol.164(10), 4991–4995 (2000).
  • Takaki R , WatsonSR, LanierLL. DAP12: an adapter protein with dual functionality. Immunol. Rev.214(1), 118–129 (2006).
  • Braak H , BraakE. Evolution of the neuropathology of Alzheimer‘s disease. Acta Neurol. Scand. Suppl.165, 3–12 (1996).
  • Verloes A , MaquetP, SadzotB, VivarioM, ThiryA, FranckG. Nasu-Hakola syndrome: polycystic lipomembranous osteodysplasia with sclerosing leucoencephalopathy and presenile dementia. J. Med. Genet.34(9), 753–757 (1997).
  • Guerreiro RJ , LohmannE, BrásJMet al. Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement. Arch. Neurol.8, 1–7 (2012).
  • Guerreiro R , WojtasA, BrásJet al. TREM2 variants in Alzheimer‘s disease. N. Engl. J. Med.368(2), 117–127 (2013).
  • Jonsson T , StefanssonH, SteinbergSet al. Variant of TREM2 associated with the risk of Alzheimer‘s disease. N. Engl. J. Med.368(2), 107–116 (2013).
  • Benitez BA , CooperB, PastorPet al. TREM2 is associated with the risk of Alzheimer‘s disease in Spanish population. Neurobiol. Aging34(6), 1711 E15–E17 (2013).
  • Pottier C , WallonD, RousseauSet al. TREM2 R47H variant as a risk factor for early-onset Alzheimer‘s disease. J. Alzheimers Dis.35(1), 45–49 (2013).
  • Guerreiro R , WojtasA, BrasJet al. TREM2 variants in Alzheimer‘s disease. N. Engl. J. Med.368(2), 117–127 (2013).
  • N‘Diaye EN , BrandaCS, BrandaSSet al. TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria. J. Cell Biol.184(2), 215–223 (2009).
  • Hsieh CL , KoikeM, SpustaSCet al. A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J. Neurochem.109(4), 1144–1156 (2009).
  • Melchior B , GarciaAE, HsiungBKet al. Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer‘s disease. ASN Neuro.2(3), e00037 (2010).
  • Zhao Y , BhattacharjeeS, JonesBMet al. Regulation of TREM2 expression by an NF-κB-sensitive miRNA-34a. Neuroreport24(6), 318–323 (2013).
  • Jimenez S , Baglietto-VargasD, CaballeroCet al. Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer‘s disease: age-dependent switch in the microglial phenotype from alternative to classic. J. Neurosci.28(45), 11650–11661 (2008).
  • Bansal V , LibigerO, TorkamaniA, SchorkNJ. Statistical analysis strategies for association studies involving rare variants. Nat. Rev. Genet.11(11), 773–785 (2010).
  • Zheng HF , LadouceurM, GreenwoodCM, RichardsJB. Effect of genome-wide genotyping and reference panels on rare variants imputation. J. Genet. Genomics39(10), 545–550 (2012).
  • Tennessen JA , BighamAW, O‘Connoret al. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science337(6090), 64–69 (2012).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.