Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 3
209
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Regulation profile of phosphatidylcholines (PCs) and lysophosphatidylcholines (LPCs) components towards UDP-glucuronosyltransferases (UGTs) isoforms

, , , , , , , , , , & show all
Pages 197-206 | Received 07 Aug 2014, Accepted 12 Sep 2014, Published online: 26 Sep 2014

References

  • Bock KW, Kohle C. (2005). UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects. Methods Enzymol 400:57–75
  • Diatlovitskaia EV, Lemenovskaia AF, Archakov AI, et al. (1977). Alteration of the lipid composition of rat liver microsomes on reconstitution of the cytochrom P-450 system. Inactivation of the enzyme by lysolecithin. Biokhimiia 42:139–43
  • Diatlovitskaia EV, Petkova DKH, Bergel'son LD. (1982). Lipid dependence of the activity of cytochrome P-450 from microsomes of rat liver by the phosphatidylcholine transfer protein from bovine liver. Biokhimiia 47:1366–9
  • Dragacci S, Thomassin J, Magdalou J, et al. (1987). Properties of human hepatic UDP-glucuronosyltransferases. Relationship to other inducible enzymes in patients with cholestasis. Eur J Clin Pharmacol 32:485–91
  • Dura P, Salomon J, Te Morsche RH, et al. (2012). High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk. Int J Oncol 40:1789–96
  • Fang ZZ, Cao YF, Hu CM, et al. (2013a). Structure-inhibition relationship of ginsenosides towards UDP-glucuronosyltransferases (UGTs). Toxicol Appl Pharmacol 267:149–54
  • Fang ZZ, He RR, Cao YF, et al. (2013b). A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders. J Lipid Res 54:3334–44
  • Fang ZZ, Krausz KW, Tanaka N, et al. (2013c). Metabolomics reveals trichloroacetate as a major contributor to trichloroethylene-induced metabolic alterations in mouse urine and serum. Arch Toxicol 87:1975–87
  • Han MS, Lim YM, Quan W, et al. (2011). Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance. J Lipid Res 52:1234–46
  • Ishii Y, An K, Nishimura Y, Yamada H. (2012). ATP serves as an endogenous inhibitor of UDP-glucuronosyltransferase (UGT): a new insight into the latency of UGT. Drug Metab Dispos 40:2081–9
  • Kokawa Y, Kishi N, Jinno H, et al. (2013). Effect of UDP-glucuronosyltransferase 1A8 polymorphism on raloxifene glucuronidation. Eur J Pharm Sci 49:199–205
  • Lagace TA, Ridgway ND. (2013). The role of phospholipids in the biological activity and structure of the endoplasmic reticulum. Biochim Biophys Acta 1833:2499–510
  • Mackenzie PI. (2000). Identification of uridine diphosphate glucuronosyl transferases involved in the metabolism and clearance of mycophenolic acid. Ther Drug Monit 22:10–3
  • Matsumoto T, Kobayashi T, Kamata K. (2007). Role of lysophosphatidylcholine (LPC) in atherosclerosis. Curr Med Chem 14:3209–20
  • Meza-Junco J, Chu QS, Christensen O, et al. (2009). UGT1A1 polymorphism and hyperbilirubinemia in a patient who received sorafenib. Cancer Chemother Pharmacol 65:1–4
  • Tsoutsikos P, Miners JO, Stapleton A, et al. (2004). Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7. Biochem Pharmacol 67:191–9
  • Uchaipichat V, Mackenzie PI, Elliot DJ, Miners JO. (2006). Selectivity of substrate (trifl uoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfi npyrazone) “probes” for human UDP-glucuronosyltransferases. Drug Metab Dispos 34:449–56
  • Wenk MR. (2005). The emerging field of lipidomics. Nat Rev Drug Discov 4:594–610
  • Xiao Y, Guengerich FP. (2012). Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipids. J Lipid Res 53:1610–7
  • Zakim D, Eibl H. (1992). The influence of charge and the distribution of charge in the polar region of phospholipids on the activity of UDP-glucuronosyltransferase. J Biol Chem 267:13166–70
  • Zucker SD, Qin X, Rouster SD, et al. (2001). Mechanism of indinavir-induced hyperbilirubinemia. Proc Natl Acad Sci USA 98:12671–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.