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Original Articles

Fatal overdose from synthetic cannabinoids and cathinones in Japan: demographics and autopsy findings

, MD, , MD, PhD, , MT & , MD
Pages 520-529 | Received 25 Jan 2016, Accepted 25 Mar 2016, Published online: 09 Jun 2016

References

  • Kamijo Y, Takai M, Fujita Y, Hirose Y, Iwasaki Y, Ishihara S, Yokoyama T, et al. A multicenter retrospective survey of poisoning after consumption of products containing synthetic chemicals in Japan. Int Med 2014;53:2439–2445.
  • Kesha K, Boggs CL, Ripple MG, Allan CH, Levine B, Jufer-Phipps R, Doyon S, et al. Methylenedioxypyrovalerone (“bath salts”), related death: case report and review of the literature. J Forensic Sci 2013;58:1654–1659.
  • Kaye S, Darke S, Duflou J, McKetin R. Methamphetamine-related fatalities in Australia: demographics, circumstances, toxicology and major organ pathology. Addiction 2008;103:1353–1360.
  • Zhu BL, Oritani S, Shimotouge K, Ishida K, Quan L, Fujita MQ, Ogawa M, Maeda H. Methamphetamine-related fatalities in forensic autopsy during 5 years in the southern half of Osaka city and surrounding areas. Forensic Sci Int 2000;113:443–447.
  • Logan BK, Fligner CL, Haddix T. Cause and manner of death in fatalities involving methamphetamine. J Forensic Sci 1998;43:28–34.
  • Nakao K, Shimada R, Hara K, Kibayashi K. Experimental study on age estimation of bloodstains based on biological and toxicological analysis. Open Forensic Sci J 2013; 6, 6–11.
  • Marinetti LJ, Antonides HM. Analysis of synthetic cathinones commonly found in bath salts in human performance and postmortem toxicology: method development, drug distribution and interpretation of results. J Anal Toxicol 2013;37:135–146.
  • Suarez-Mier MP, Aguilera B, Mosquera RM, Sanchez-de-Leon MS. Pathology of sudden death during recreational sports in Spain. Forensic Sci Int 2013;226:188–196.
  • DiMaio VJ. Excited delirium syndrome: cause of death and prevention. Boca Raton, FL: CRC/Taylor & Francis; 2006.
  • Penders TM, Gestring RE, Vilensky DA. Excited delirium following use of synthetic cathinones (bath salts). Gen Hosp Psychiatry 2012;34:647–650.
  • Shanks KG, Winston D, Heidingsfelder J, Behonick G. Case reports of synthetic cannabinoid XLR-11 associated fatalities. Forensic Sci Int 2015;252:e6–9.
  • Behonick G, Shanks KG, Firchau DJ, Mathur G, Lynch CF, Nashelsky M, Jaskierny DJ, Meroueh C. Four postmortem case reports with quantitative detection of the synthetic cannabinoid, 5F-PB-22. J Anal Toxicol 2014;38:559–562.
  • Cosbey SH, Peters KL, Quinn A, Bentley A. Mephedrone (methylmethcathinone) in toxicology casework: a Northern Ireland perspective. J Anal Toxicol 2013;37:74–82.
  • Wyman JF, Lavins ES, Engelhart D, Armstrong EJ, Snell KD, Boggs PD, Taylor SM, et al. Postmortem tissue distribution of MDPV following lethal intoxication by “bath salts”. J Anal Toxicol 2013;37:182–185.
  • Wikstrom M, Thelander G, Dahlgren M, Kronstrand R. An accidental fatal intoxication with methoxetamine. J Anal Toxicol 2013;37:43–46.
  • Aromatario M, Bottoni E, Santoni M, Ciallella C. New “lethal highs”: a case of a deadly cocktail of GHB and Mephedrone. Forensic Sci Int 2012;223:e38–41.
  • Cawrse BM, Levine B, Jufer RA, Fowler DR, Vorce SP, Dickson AJ, Holler JM. Distribution of methylone in four postmortem cases. J Anal Toxicol 2012;36:434–439.
  • Pearson JM, Hargraves TL, Hair LS, Massucci CJ, Frazee CC, 3rd, Garg U, Pietak BR. Three fatal intoxications due to methylone. J Anal Toxicol 2012;36:444–451.
  • Murray BL, Murphy CM, Beuhler MC. Death following recreational use of designer drug “bath salts” containing 3,4-Methylenedioxypyrovalerone (MDPV). J Med Toxicol Off J Am Coll Med Toxicol 2012;8:69–75.
  • Maskell PD, De Paoli G, Seneviratne C, Pounder DJ. Mephedrone (4-methylmethcathinone)-related deaths. J Anal Toxicol 2011;35:188–191.
  • Dickson AJ, Vorce SP, Levine B, Past MR. Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin. J Anal Toxicol 2010;34:162–168.
  • Torrance H, Cooper G. The detection of mephedrone (4-methylmethcathinone) in 4 fatalities in Scotland. Forensic Sci Int 2010;202:e62–63.
  • Karila L, Megarbane B, Cottencin O, Lejoyeux M. Synthetic Cathinones: a new public health problem. Curr Neuropharmacol 2015;13:12–20.
  • Al-Motarreb A, Briancon S, Al-Jaber N, Al-Adhi B, Al-Jailani F, Salek MS, Broadley KJ. Khat chewing is a risk factor for acute myocardial infarction: a case-control study. Br J Clin Pharmacol 2005;59:574–581.
  • Baker KE, Herbert AA, Broadley KJ. Vasoconstriction of porcine left anterior descending coronary artery by ecstasy and cathinone is not an indirect sympathomimetic effect. Vasc Pharmacol 2007;47:10–17.
  • Suzuki H, Kawai S, Aizawa T, Kato K, Sunayama S, Okada R, Yamaguchi H. Histological evaluation of coronary plaque in patients with variant angina: relationship between vasospasm and neointimal hyperplasia in primary coronary lesions. J Am Coll Cardiol 1999;33:198–205.
  • Packe GE, Garton MJ, Jennings K. Acute myocardial infarction caused by intravenous amphetamine abuse. Br Heart J 1990;64:23–24.
  • Haft JI, Kranz PD, Albert FJ, Fani K. Intravascular platelet aggregation in the heart induced by norepinephrine. Microscopic studies. Circulation 1972;46:698–708.
  • Lusthof KJ, Oosting R, Maes A, Verschraagen M, Dijkhuizen A, Sprong AG. A case of extreme agitation and death after the use of mephedrone in The Netherlands. Forensic Sci Int 2011;206:e93–95.
  • Vilke GM, Bozeman WP, Dawes DM, Demers G, Wilson MP. Excited delirium syndrome (ExDS): treatment options and considerations. J Forensic Leg Med 2012;19:117–121.
  • Marshall BD, Galea S, Wood E, Kerr T. Injection methamphetamine use is associated with an increased risk of attempted suicide: a prospective cohort study. Drug Alcohol Depend 2011;119:134–137.
  • The White Paper on Poice (in Japanese). 2014;133

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