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Short Report

DNA damage: beta zero versus beta plus thalassemia

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Pages 585-588 | Received 26 Apr 2014, Accepted 29 Oct 2014, Published online: 26 Dec 2014

References

  • Amer J, Atlas D, Fibach E. 2008. N-acetylcysteine amide (AD4) attenuates oxidative stress in beta-thalassemia blood cells. Biochim Biophys Acta 1780:249–255
  • Amer J, Goldfarb A, Fibach E. 2004. Flow cytometric analysis of the oxidative status of normal and thalassemic red blood cells. Cytometry A 60:73–80
  • Bain BJ. 2004. A beginner’s guide to Blood cells. 2nd ed. USA: Blackwell Publishing. p 56
  • Chakraborty I, Mitra S, Gachhui R, Kar M. 2010. Non-haem iron-mediated oxidative stress in haemoglobin E beta-thalassaemia. Ann Acad Med Singapore 9:13–16
  • Dana M, Prus E, Fibach E. 2012. Thalassemic DNA-containing red blood cells are under oxidative stress. Anemia 2012:943–974
  • Elsayh KI, Zahran AM, El-Abaseri TB, Mohamed AO, El-Metwally TH. 2013. Hypoxia biomarkers, oxidative stress, and circulating microparticles in pediatric patients with thalassemia in upper Egypt. Clin Appl Thromb Hemost 20:536–545
  • Ferro E, Visalli G, Civa R, La Rosa MA, Randazzo Papa G, Baluce B, D'Ascola DG, et al. 2012. Oxidative damage and genotoxicity biomarkers in transfused and untransfused thalassemic subjects. Free Radic Biol Med 53:1829–1837
  • Fibach E, Rachmilewitz EA. 2010. The role of Antioxidants and Iron Chelators in the treatment of oxidative stress in thalassemia. Ann NY Acad Sci 1202:10–16
  • Kong Y, Zhou S, Kihm AJ, Katein AM, Yu X, Gell DA, Mackay JP, et al. 2004. Loss of α-hemoglobin–stabilizing protein impairs erythropoiesis and exacerbates β-thalassemia. J Clin Invest 114:1457–1466
  • Kósa Z, Nagy T, Nagy E, Fazakas F, Góth L. 2012. Decreased blood catalase activity is not related to specific beta-thalassemia mutations in Hungary. Int J Lab Hematol 34:172–178
  • Kumar R, Sharma DC, Kishor P. 2012. Hemoglobin E/beta thalassemia the second most common cause of transfusion dependent beta thalassemia in the Gwalior-Chambal region of central India. Hemoglobin 36:485–490
  • Naithani R, Chandra J, Bhattacharjee J, Verma P, Narayan S. 2006. Peroxidative stress and antioxidant enzymes in children with beta-thalassemia major. Pediatr Blood Cancer 46:780–785
  • Neufeld EJ. 2010. Update on Iron Chelators in Thalassemia. ASH Education Book 2010:451–455
  • Pavlova LE, Savov VM, Petkov HG, Charova IP. 2007. Oxidative stress in patients with beta-thalassemia major. Prilozi 28:145–154
  • Scott MD. 2006. H2O2 injury in beta thalassemic erythrocytes: protective role of catalase and the prooxidant effects of GSH. Free Radic Biol Med 40:1264–1272
  • Singh NP, McCoy MT, Tice RR, Schneider EL. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184–191
  • Waseem F, Khemomal KA, Sajid R. 2011. Antioxidant status in beta thalassemia major: a single-center study. Indian J Pathol Microbiol 54:761–763

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