Outcome of Pediatric Acquired Aplastic Anemia: A Developing World Experience

REFERENCES

• Guinan EC. Acquired aplastic anemia in childhood. Hematol Oncol Clin North Am. 2009;23:171–191.
   PubMedGoogle Scholar
• Young NS. Acquired aplastic anemia. Annals Int Med. 2002;136:534–546.
   PubMed Web of Science ®Google Scholar
• Locasciulli A, Oneto R, Bacigalupo A, et al. Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplant Group. Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppressive treatment in the last decade: a report from the European Group for Blood and Marrow Transplantation (EBMT). Haematologica. 2007;92:11–18.
   PubMed Web of Science ®Google Scholar
• Fuhrer M, Rampf U, Baumann I, Immunosuppressive therapy for aplastic anemia in children: a more severe disease predicts better survival. Blood. 2005;106:2102–2104.
   PubMed Web of Science ®Google Scholar
• Kojima S, Horibe K, Inaba J, Long-term outcome of acquired aplastic anaemia in children: comparison between immunosuppressive therapy and bone marrow transplantation. Br J Haematol. 2000;111:321–328.
   PubMed Web of Science ®Google Scholar
• Feng YH, Yen CJ, Huang WT, Clinical response of antilymphocyte globulin-based treatment in patients in Taiwan with aplastic anemia: positive hepatitis C antibody may represent a response predictor. Int J Hematol. 2004;79:133–137.
   PubMedGoogle Scholar
• Kojima S, Hibi S, Kosaka Y, Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia. Blood. 2000;96:2049–2054.
   PubMed Web of Science ®Google Scholar
• de-Medeiros CR, Ribeiro RC, Bittencourt MA, Long-term outcome of 25 children and adolescents with severe aplastic anemia treated with antithymocyte globulin. Braz J Med Biol Res. 2000;33:553–558.
   PubMedGoogle Scholar
• Pongtanakul B, Das PK, Charpentier K, Dror Y. Outcome of children with aplastic anemia treated with immunosuppressive therapy. Pediatr Blood Cancer. 2008;50:52–57.
   PubMed Web of Science ®Google Scholar
• Young NS, Calado RT, Scheinberg P. Current concepts in the pathophysiology and treatment of aplastic anemia. Blood. 2006;108:2509–2519.
   PubMed Web of Science ®Google Scholar
• Nair V, Sondhi V, Sharma A, Survival after immunosuppressive therapy in children with aplastic anemia. Indian Pediatr. 2012:49(16);371–376.
   PubMedGoogle Scholar
• Sharma R, Chandra J, Sharma S, Antithymocyte globulin and cyclosporin in children with acquired aplastic anemia. A developing country experience. J Pediatr Hematol Oncol. 2012;34(2): 93–95.
   PubMedGoogle Scholar
• Gupta V, Kumar A, Tilak V, Immunosuppressive therapy in aplastic anemia. Indian J Pediatr. 2012;79(12):1587–1591. DOI 10.1007/s12098–012–0691–2.
   PubMed Web of Science ®Google Scholar
• George B, Mathews V, Viswabandya A, Allogeneic hematopoietic stem cell transplantation is superior to immunosuppressive therapy in Indian children with aplastic anemia—a single center analysis of 100 patients. Pediatr Hematol Oncol. 2010;27:122–131.
   PubMed Web of Science ®Google Scholar
• Kobayashi R, Yabe H, Hara J, Preceding immunosuppressive therapy with antithymocyte globulin and cyclosporin increases the incidence of graft rejection in children with aplastic anaemia who underwent allogeneic bone marrow transplantation from HLA-identical siblings. Br J Haematol. 2006;135:693–696.
   PubMed Web of Science ®Google Scholar
• Camitta BM, Thomas ED, Nathan DG, Severe aplastic anemia: a prospective study of the effect of early marrow transplantation on acute mortality. Blood. 1976;48:63–70.
   PubMed Web of Science ®Google Scholar
• Marsh JC, Ball SE, Cavenagh J, Guidelines for the diagnosis and management of aplastic anaemia. Br J Haematol. 2009;147:43–70.
   PubMed Web of Science ®Google Scholar
• Camitta BM. What is the definition of cure for aplastic anemia? Acta Haematol. 2000;103:16–18.
   PubMed Web of Science ®Google Scholar
• Kennedy-Nasser AA, Leung KS, Mahajan A, Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia. Biol Blood Marrow Transplant. 2006;12:1277–1284.
   PubMed Web of Science ®Google Scholar
• Munoz Villa A, Ortega Aramburu JJ, Bureo Dacal E, Allogeneic bone marrow transplantation in children with severe acquired aplastic anemia. The long-term results. The Spanish Group for Bone Marrow Transplantation in Children (GETMON). An Esp Pediatr. 1999;50:29–32.
   PubMedGoogle Scholar
• Azuma E, Kojima S, Kato K, Conditioning with cyclophosphamide/antithymocyte globulin for allogeneic bone marrow transplantation from HLA-matched siblings in children with severe aplastic anemia. Bone Marrow Transplant. 1997;19:1085–1087.
   PubMedGoogle Scholar
• Kahl C, Leisenring W, Deeg HJ, Cyclophosphamide and antithymocyte globulin as a conditioning regimen for allogeneic marrow transplantation in patients with aplastic anaemia: a long term follow-up. Br J Haematol. 2005;130:747–751.
   PubMed Web of Science ®Google Scholar
• Schrezenmeier H, Passweg JR, Marsh JC, Worse outcome and more chronic GVHD with peripheral blood progenitor cells than bone marrow in HLA-matched sibling donor transplants for young patients with severe acquired aplastic anemia. Blood. 2007;110:1397–1400.
   PubMed Web of Science ®Google Scholar
• Lo Ten Foe JR, Kwee ML, Rooimans MA, Somatic mosaicism in Fanconi anemia: molecular basis and significance. Eur J Hum Genet. 1997;5:137–148.
   PubMedGoogle Scholar
• Federman N, Sakamoto KM. The genetic basis of bone marrow failure syndromes in children. Mol Genet Metab. 2005;86:100–109.
   PubMed Web of Science ®Google Scholar
• Calado RT, Graf SA, Wilkerson KL, Mutations in the SBDS gene in acquired aplastic anemia. Blood. 2007;110:1141–1146.
   PubMedGoogle Scholar
• Dokal I. Inherited aplastic anaemia. Hematology J. 2003;4: 3–9.
   Google Scholar
• Yamaguchi H, Calado RT, Ly H, Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. N Engl J Med. 2005;352:1413–1424.
   PubMed Web of Science ®Google Scholar
• Ortmann CA, Niemeyer CM, Wawer A, TERC mutations in children with refractory cytopenia. Haematologica. 2006;91:707–708.
   PubMedGoogle Scholar
• Solomou EE, Gibellini F, Stewart B, Perforin gene mutations in patients with acquired aplastic anemia. Blood. 2007;109:5234–5237.
   PubMed Web of Science ®Google Scholar
• Varma N, Varma S, Marwaha RK Multiple constitutional aetiological factors in bone marrow failure syndrome (BMFS) patients from north India. Indian J. Med. Res. 2006;124(1):51.
   PubMed Web of Science ®Google Scholar
• Jain D, Raina V, Fauzdar A, Chromosomal breakage study in aplastic anemia patients in India. Asian J Med Sci. 2010;2(5): 227–232.
   Google Scholar
• Gupta V, Tripathi S, Singh TB, A study of bone marrow failure syndrome in children. Indian J Med Sci. 2008;62:13–18.
   PubMedGoogle Scholar
• Gillio AP, Boulad F, Small TN, Comparison of long-term outcome of children with severe aplastic anemia treated with immunosuppression versus bone marrow transplantation. Biol Blood Marrow Transplant. 1997;3:18–24.
   PubMedGoogle Scholar
• Agarwal MB, Agarwal UM, Bhave AB, Antilymphocyteglobulin therapy in acquired aplastic anaemia. J Assoc Physicians India. 1993;41:371–373.
   PubMedGoogle Scholar
• Kulkarni S, Sastry S, Saikia TK Antilymphoglobulin (ALG) or antithymocyte globulin (ATG) with methylprednisone and oxymethalone in aplastic anemia. J Assoc Physicians India. 1997;45(4):263–266.
   PubMedGoogle Scholar
• Passweg JR, Perez WS, Eapen M, Bone marrow transplants from mismatched related and unrelated donors for severe aplastic anemia. Bone Marrow Transplant. 2006;37:641–649.
   PubMed Web of Science ®Google Scholar
• Gluckman E, Rocha V, Chastang C. European results of unrelated cord blood transplants. Eurocord group. Bone Marrow Transplant. 1998;21(Suppl 3):S87–S91.
   Google Scholar
• Tzeng CH, Chen PM, Fan S, CY/TBI-800 as a pretransplant regimen for allogeneic bone marrow transplantation for severe aplastic anemia using HLA-haploidentical family donors. Bone Marrow Transplant. 1996;18:273–277.
   PubMed Web of Science ®Google Scholar
• Yadav SP, Dua V, Sachdeva A. Sepsis is a major barrier to improving survival in childhood acute lymphoblastic leukemia in the developing World. J Pediatr Hematol Oncol. 2011;33:636.
   PubMed Web of Science ®Google Scholar