Association of genetic variation in IKZF1, ARID5B, CDKN2A, and CEBPE with the risk of acute lymphoblastic leukemia in Tunisian children and their contribution to racial differences in leukemia incidence

References

• Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev. 2010;36:277–285
   PubMed Web of Science ®Google Scholar
• Pui CH, Relling MV, Downing JR. Acute lymphoblastic leukemia. N Engl J Med. 2004;350:1535–1548.
   PubMed Web of Science ®Google Scholar
• Mbanya DN, Minkoulou EM, Kaptue LN. HIV-1 infection in adults with haematological malignancies in Yaounde, Cameroon. West Afr J Med. 2002; 21:183–184.
   PubMedGoogle Scholar
• Urayama KY, Chokkalingam AP, Manabe A, Mizutani S. Current evidence for an inherited genetic basis of childhood acute lymphoblastic leukemia. Int J Hematol. 2013;97:3–19.
   PubMed Web of Science ®Google Scholar
• Vijayakrishnan J, Houlston RS. Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica. 2010;95:1405–14.
   PubMed Web of Science ®Google Scholar
• Sherborne AL, Hosking FJ, Prasad RB, et al. Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Nat Genet. 2010;42:492–494.
   PubMed Web of Science ®Google Scholar
• Trevino LR, Yang W, French D, et al. Germline genomic variants associated with childhood acute lymphoblastic leukemia. Nat Genet. 2009;41:1001–1005.
   PubMed Web of Science ®Google Scholar
• Harker N, Naito T, Cortes M, et al. The CD8alpha gene locus is regulated by the Ikaros family of proteins. Mol Cell. 2002;10:1403–1415.
   PubMed Web of Science ®Google Scholar
• Lahoud MH, Ristevski S, Venter DJ, et al. Gene targeting of Desrt, a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs. Genome Res. 2001;11:1327–1334.
   PubMed Web of Science ®Google Scholar
• Patsialou A, Wilsker D, Moran E. DNA-binding properties of ARID family proteins. Nucleic Acids Res. 2005;33:66–80.
   PubMed Web of Science ®Google Scholar
• Wilsker D, Patsialou A, Dallas PB, Moran E. ARID proteins: a diverse family of DNA binding proteins implicated in the control of cell growth, differentiation, and development. Cell Growth Differ. 2002;13:95–106.
   PubMedGoogle Scholar
• Akagi T, Thoennissen NH, George A, et al. In vivo deficiency of both C/EBPβ and C/EBPϵ results in highly defective myeloid differentiation and lack of cytokine response. PLoS ONE. 2010;5:e15419.
   Google Scholar
• Robertson KD, Jones PA. Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus. Oncogene. 1999;18:3810–3820.
   PubMed Web of Science ®Google Scholar
• Ye J, Coulouris G, Zaretskaya I, Cutcutache I, Rozen S, Madden TL. Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. BMC Bioinformatics. 2012;13:134.
   PubMedGoogle Scholar
• Team RC. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2012.
   Google Scholar
• Gutierrez-Camino A, Lopez-Lopez E, Martin-Guerrero I, et al. Intron 3 of the ARID5B gene: a hot spot for acute lymphoblastic leukemia susceptibility. J Cancer Res Clin Oncol. 2013;139:1879–1886.
   PubMed Web of Science ®Google Scholar
• Papaemmanuil E, Hosking FJ, Vijayakrishnan J, et al. Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet. 2009;41:1006–1010.
   PubMed Web of Science ®Google Scholar
• Lin CY, Li MJ, Chang JG, et al. High-resolution melting analyses for genetic variants in ARID5B and IKZF1 with childhood acute lymphoblastic leukemia susceptibility loci in Taiwan. Blood Cells Mol Dis. 2014;52:140–145.
   PubMed Web of Science ®Google Scholar
• Vijayakrishnan J, Sherborne AL, Sawangpanich R, Hongeng S, Houlston RS, Pakakasama S. Variation at 7p12.2 and 10q21.2 influences childhood acute lymphoblastic leukemia risk in the Thai population and may contribute to racial differences in leukemia incidence. Leuk Lymphoma. 2010; 51:1870–1874.
   PubMed Web of Science ®Google Scholar
• Georgopoulos K, Bigby M, Wang JH, et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell. 1994;79:143–156.
   PubMed Web of Science ®Google Scholar
• Pastorczak A, Gorniak P, Sherborne A, et al. Role of 657del5 NBN mutation and 7p12.2 (IKZF1), 9p21 (CDKN2A), 10q21.2 (ARID5B) and 14q11.2 (CEBPE) variation and risk of childhood ALL in the Polish population. Leuk Res. 2011;35:1534–1536.
   PubMed Web of Science ®Google Scholar
• Prasad RB, Hosking FJ, Vijayakrishnan J, et al. Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood. Blood. 2010;115:1765–1767.
   PubMed Web of Science ®Google Scholar
• Ross JA, Linabery AM, Blommer CN, et al. Genetic variants modify susceptibility to leukemia in infants: a Children's Oncology Group report. Pediatr Blood Cancer. 2013;60:31–34.
   PubMed Web of Science ®Google Scholar
• Lautner-Csorba O, Gezsi A, Semsei AF, et al. Candidate gene association study in pediatric acute lymphoblastic leukemia evaluated by Bayesian network based Bayesian multilevel analysis of relevance. BMC Med Genomics. 2012;5:42.
   PubMedGoogle Scholar
• Akasaka T, Balasas T, Russell LJ, et al. Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood. 2007;109:3451–3461.
   PubMed Web of Science ®Google Scholar
• Orsi L, Rudant J, Bonaventure A, et al. Genetic polymorphisms and childhood acute lymphoblastic leukemia: GWAS of the ESCALE study (SFCE). Leukemia. 2012;26:2561–2564.
   PubMed Web of Science ®Google Scholar
• Ellinghaus E, Stanulla M, Richter G, et al. Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia. Leukemia. 2012;26:902–909.
   PubMed Web of Science ®Google Scholar