References
- Shirai H, Blundell TL, Mizuguchi K. A novel superfamily of enzymes that catalyze the modification of guanidino groups. Trends Biochem Sci 2001;26:465–8
- Wegner N, Lundberg K, Kinloch A, et al. Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis. Immunol Rev 2010;233:34–54
- Suzuki A, Yamada R, Yamamoto K. Citrullination by peptidylarginine deiminase in rheumatoid arthritis. Ann NY Acad Sci 2007;1108:323–39
- Wood DD, Bilbao JM, O’Connors P, Moscarello MA. Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein. Ann Neurolog 1996;40:18–24
- Ishigami A, Ohsawa T, Hiratsuka M, et al. Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. J Neurosci Res 2005;1:120–8
- Mohlake P, Whiteley CG. Arginine metabolising enzymes as therapeutic tools for Alzheimer's disease: peptidyl arginine deiminase catalyses fibrillogenesis of beta-amyloid peptides. Mol Neurobiol 2010;41:149–58
- Jang B, Jin JK, Jeong YC, et al. Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease. Annals Neuropathol 2009;119:199–210
- Knight JS, Zhao W, Luo W, et al. Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. J Clin Invest 2013;7:2981–93
- Rohrbach AS, Slade DJ, Thompson PR, Mowen KA. Activation of PAD4 in NET formation. Front Immunol 2012;3:360. doi: 10.3389/fimmu.2012.00360
- Sunish M, Cherrington BD, Horibata S, et al. Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis. Biochem Res Int 2012;2012:895343. doi: 10.1155/2012/895343
- Bicker KL, Thompson PR. The protein arginine deiminases: structure, function, inhibition, and disease. Biopolymers 2013;2:155–63
- Shirai H, Blundell TL, Mizuguchi K. A novel superfamily of enzymes that catalyze the modification of guanidino groups. Trends Biochem Sci 2001;26:465–8
- Shirai H, Mokrab Y, Mizuguchi, K. The guanidino-group modifying enzymes: structural basis for their diversity and commonality. Proteins 2006;4:1010–23
- Senshu T, Aliyama K, Ishigami A, Nomura K. Studies on specificity of peptidylarginine deiminase reactions using an immunochemical probe that recognizes an enzymatically deiminated partial sequence of mouse keratin K1. J Dermatol Sci 1999;21:113–26
- Yamamoto I, Senshu T, Eady RA, et al. Sequential reorganization of cornified cell keratin filaments involving filaggrin-mediated compaction and keratin 1 deimination. J Invest Dermatol 2002;118:282–7
- Moscarello MA, Pritzker LB, Mastronardi FG, Wood DD. Peptidylarginine deiminase: a candidate factor in demyelinating disease. J Neurochem 2002;81:335–43
- Kanno T, Kawada A, Yamanouchi J, et al. Human peptidylarginine deiminase type III: molecular cloning and nucleotide sequence of the cDNA, properties of the recombinant enzyme, and immunohistochemical localization in human skin. J Invest Dermatol 2000;115:813–23
- Rogers G, Winter B, McLaughlan C, et al. Peptidylarginine deiminase of the hair follicle: characterization, localization, and function in keratinizing tissues. J Invest Dermatol 1997;108:700–7
- Nakashima K, Hagiwara T, Ishigami A, et al. Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3). J Biol Chem 1999;274:27786–92
- Hagiwara T, Nakashima K, Hirano H, et al. Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes. Biochem Biophys Res Commun 2002;290:979–83
- Nakashima K, Hagiwara T, Yamada M. Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes. J Biol Chem 2002;277:49562–8
- Chavanas S, Méchin MC, Takahara H, et al. Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6. Gene 2004;330:19–27
- Wright PW, Bolling LC, Calvert ME, et al. ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets. Dev Biol 2003;256:73–88
- Arita K, Hashimoto H, Shimizu T, et al. Structural basis for Ca(2+)-induced activation of human PAD4. Nat Struct Biol 2004;11:777–83
- Wonhwa C. Membrane targeting by C1 and C2 domains. J Biol Chem 2001;276:32407–10
- Lewis RS. Calcium signaling mechanisms in T lymphocytes. Annu Rev Immunol 2001;19:497–521
- Takahara H, Tsuchida M, Kusubata M, et al. Peptidylarginine deiminase of the mouse. Distribution, properties, and immunocytochemical localization. J Biol Chem 1989;264:13361–8
- Thompson PR, Fast W. Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock? ACS Chem Biol 2006;7:433–41
- Slack JL, Causey CP, Thompson PR. Protein arginine deiminase 4: a target for an epigenetic cancer therapy. Cell Mol Life Sci 2011;68:709–20
- Lianhu W, Wasilewski E, Kumar Chakka S, et al. Novel inhibitors of protein arginine deiminase with potential activity in multiple sclerosis animal model. J Med Chem 2013;56:1715–22
- Kearney PL, Bhatia M, Jones NG, et al. Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis. Biochemistry 2005;44:10570–82
- Galkin A, Lu X, Dunaway-Mariano D, Herzberg O. Michaelis complex and the thiouronium reaction intermediate of Pseudomonas aeruginosa arginine deiminase. J Biol Chem 2005;280:34080–7
- Dreyton CJ, Anderson ED, Subramanian V, et al. Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation. Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation. Bioorg Med Chem 2014;22:1362–9
- Trabocchi A, Menchi G, Cini N, et al. Click-chemistry-derived triazole ligands of arginine-glycine-aspartate (RGD) integrins with a broad capacity to inhibit adhesion of melanoma cells and both in vitro and in vivo angiogenesis. J Med Chem 2010;53:7119–28
- Bozdag M, Dreker T, Henry C, et al. Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors. Bioorg Med Chem Lett 2013;23:715–19
- Yuki H, Ohmura T, Kawasaki H, et al. Clinical analysis of urea nitrogen: chemical structure of the colored reaction product of urea with diacetylmonoxime and thiosemicarbazide. Chem Pharm Bull 1981;29:1096–100
- Sugawara K, Oyama O. Fluorogenic reaction and specific microdetermination of ammonia. J Biochem 1981;89:771–4
- Sternson LA, Stobaugh JF, Repta A. Rational design and evaluation of improved o-phthalaldehyde-like fluorogenic reagents. J Anal Biochem 1985;144:233–46
- Mana H. Rapid and selective determination of ammonium by fluorimetric flow injection analysis. [PhD Thesis]. Martin-Luther-Universität Halle-Wittenberg; November 1998