Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver

References

• Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 2006; 160:1 - 40; http://dx.doi.org/10.1016/j.cbi.2005.12.009; PMID: 16430879
   PubMed Web of Science ®Google Scholar
• Rubino JT, Franz KJ. Coordination chemistry of copper proteins: how nature handles a toxic cargo for essential function. J Inorg Biochem 2012; 107:129 - 43; http://dx.doi.org/10.1016/j.jinorgbio.2011.11.024; PMID: 22204943
   PubMed Web of Science ®Google Scholar
• Kim BE, Nevitt T, Thiele DJ. Mechanisms for copper acquisition, distribution and regulation. Nat Chem Biol 2008; 4:176 - 85; http://dx.doi.org/10.1038/nchembio.72; PMID: 18277979
   PubMed Web of Science ®Google Scholar
• Wang Y, Hodgkinson V, Zhu S, Weisman GA, Petris MJ. Advances in the understanding of mammalian copper transporters. Adv Nutr 2011; 2:129 - 37; http://dx.doi.org/10.3945/an.110.000273; PMID: 22332042
   PubMed Web of Science ®Google Scholar
• Rae TD, Schmidt PJ, Pufahl RA, Culotta VC, O’Halloran TV. Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase. Science 1999; 284:805 - 8; http://dx.doi.org/10.1126/science.284.5415.805; PMID: 10221913
   PubMed Web of Science ®Google Scholar
• Polio J, Enriquez RE, Chow A, Wood WM, Atterbury CE. Hepatocellular carcinoma in Wilson’s disease. Case report and review of the literature. J Clin Gastroenterol 1989; 11:220 - 4; http://dx.doi.org/10.1097/00004836-198904000-00022; PMID: 2472436
   PubMed Web of Science ®Google Scholar
• Walshe JM, Waldenström E, Sams V, Nordlinder H, Westermark K. Abdominal malignancies in patients with Wilson’s disease. QJM 2003; 96:657 - 62; http://dx.doi.org/10.1093/qjmed/hcg114; PMID: 12925721
   PubMed Web of Science ®Google Scholar
• Iwadate H, Ohira H, Suzuki T, Abe K, Yokokawa J, Takiguchi J, et al. Hepatocellular carcinoma associated with Wilson’s disease. Intern Med 2004; 43:1042 - 5; http://dx.doi.org/10.2169/internalmedicine.43.1042; PMID: 15609699
   PubMed Web of Science ®Google Scholar
• Kumagi T, Horiike N, Abe M, Kurose K, Iuchi H, Masumoto T, et al. Small hepatocellular carcinoma associated with Wilson’s disease. Intern Med 2005; 44:439 - 43; http://dx.doi.org/10.2169/internalmedicine.44.439; PMID: 15942090
   PubMed Web of Science ®Google Scholar
• Masuda R, Yoshida MC, Sasaki M, Dempo K, Mori M. High susceptibility to hepatocellular carcinoma development in LEC rats with hereditary hepatitis. Jpn J Cancer Res 1988; 79:828 - 35; http://dx.doi.org/10.1111/j.1349-7006.1988.tb00044.x; PMID: 2459092
   PubMedGoogle Scholar
• Powell CJ. Copper-overload causes cancer? The LEC rat: a model for human hepatitis, liver cancer, and much more. Hum Exp Toxicol 1994; 13:910 - 2; PMID: 7718314
   PubMed Web of Science ®Google Scholar
• Huster D, Finegold MJ, Morgan CT, Burkhead JL, Nixon R, Vanderwerf SM, et al. Consequences of copper accumulation in the livers of the Atp7b-/- (Wilson disease gene) knockout mice. Am J Pathol 2006; 168:423 - 34; http://dx.doi.org/10.2353/ajpath.2006.050312; PMID: 16436657
   PubMed Web of Science ®Google Scholar
• Gupte A, Mumper RJ. Elevated copper and oxidative stress in cancer cells as a target for cancer treatment. Cancer Treat Rev 2009; 35:32 - 46; http://dx.doi.org/10.1016/j.ctrv.2008.07.004; PMID: 18774652
   PubMed Web of Science ®Google Scholar
• Tsubota A, Matsumoto K, Mogushi K, Nariai K, Namiki Y, Hoshina S, et al. IQGAP1 and vimentin are key regulator genes in naturally occurring hepatotumorigenesis induced by oxidative stress. Carcinogenesis 2010; 31:504 - 11; http://dx.doi.org/10.1093/carcin/bgp313; PMID: 20015863
   PubMed Web of Science ®Google Scholar
• Jomova K, Valko M. Advances in metal-induced oxidative stress and human disease. Toxicology 2011; 283:65 - 87; http://dx.doi.org/10.1016/j.tox.2011.03.001; PMID: 21414382
   PubMed Web of Science ®Google Scholar
• Tsai CY, Finley JC, Ali SS, Patel HH, Howell SB. Copper influx transporter 1 is required for FGF, PDGF and EGF-induced MAPK signaling. Biochem Pharmacol 2012; 84:1007 - 13; http://dx.doi.org/10.1016/j.bcp.2012.07.014; PMID: 22842628
   PubMed Web of Science ®Google Scholar
• Finney L, Mandava S, Ursos L, Zhang W, Rodi D, Vogt S, et al. X-ray fluorescence microscopy reveals large-scale relocalization and extracellular translocation of cellular copper during angiogenesis. Proc Natl Acad Sci U S A 2007; 104:2247 - 52; http://dx.doi.org/10.1073/pnas.0607238104; PMID: 17283338
   PubMed Web of Science ®Google Scholar
• Gérard C, Bordeleau LJ, Barralet J, Doillon CJ. The stimulation of angiogenesis and collagen deposition by copper. Biomaterials 2010; 31:824 - 31; http://dx.doi.org/10.1016/j.biomaterials.2009.10.009; PMID: 19854506
   PubMed Web of Science ®Google Scholar
• Easter RN, Qilin Chan, Lai B, Ritman EL, Caruso JA, Zhenyu Qin. Vascular metallomics: copper in the vasculature. Vasc Med 2010; 15:61 - 9; http://dx.doi.org/10.1177/1358863X09346656; PMID: 19808712
   PubMed Web of Science ®Google Scholar
• Fan F, Wey JS, McCarty MF, Belcheva A, Liu W, Bauer TW, et al. Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells. Oncogene 2005; 24:2647 - 53; http://dx.doi.org/10.1038/sj.onc.1208246; PMID: 15735759
   PubMed Web of Science ®Google Scholar
• Wey JS, Fan F, Gray MJ, Bauer TW, McCarty MF, Somcio R, et al. Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines. Cancer 2005; 104:427 - 38; http://dx.doi.org/10.1002/cncr.21145; PMID: 15952180
   PubMed Web of Science ®Google Scholar
• Yang AD, Camp ER, Fan F, Shen L, Gray MJ, Liu W, et al. Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells. Cancer Res 2006; 66:46 - 51; http://dx.doi.org/10.1158/0008-5472.CAN-05-3086; PMID: 16397214
   PubMed Web of Science ®Google Scholar
• Payne SL, Hendrix MJ, Kirschmann DA. Paradoxical roles for lysyl oxidases in cancer--a prospect. J Cell Biochem 2007; 101:1338 - 54; http://dx.doi.org/10.1002/jcb.21371; PMID: 17471532
   PubMed Web of Science ®Google Scholar
• Schietke R, Warnecke C, Wacker I, Schödel J, Mole DR, Campean V, et al. The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1. J Biol Chem 2010; 285:6658 - 69; http://dx.doi.org/10.1074/jbc.M109.042424; PMID: 20026874
   PubMed Web of Science ®Google Scholar
• Li W, Nellaiappan K, Strassmaier T, Graham L, Thomas KM, Kagan HM. Localization and activity of lysyl oxidase within nuclei of fibrogenic cells. Proc Natl Acad Sci U S A 1997; 94:12817 - 22; http://dx.doi.org/10.1073/pnas.94.24.12817; PMID: 9371758
   PubMed Web of Science ®Google Scholar
• Giampuzzi M, Oleggini R, Albanese C, Pestell R, Di Donato A. beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase. Biochim Biophys Acta 2005; 1745:370 - 81; http://dx.doi.org/10.1016/j.bbamcr.2005.04.012; PMID: 15946752
   PubMed Web of Science ®Google Scholar
• Mufti AR, Burstein E, Duckett CS. XIAP: cell death regulation meets copper homeostasis. Arch Biochem Biophys 2007; 463:168 - 74; http://dx.doi.org/10.1016/j.abb.2007.01.033; PMID: 17382285
   PubMed Web of Science ®Google Scholar
• Burstein E, Ganesh L, Dick RD, van De Sluis B, Wilkinson JC, Klomp LW, et al. A novel role for XIAP in copper homeostasis through regulation of MURR1. EMBO J 2004; 23:244 - 54; http://dx.doi.org/10.1038/sj.emboj.7600031; PMID: 14685266
   PubMed Web of Science ®Google Scholar
• Wenger RH. Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. FASEB J 2002; 16:1151 - 62; http://dx.doi.org/10.1096/fj.01-0944rev; PMID: 12153983
   PubMed Web of Science ®Google Scholar
• Martin F, Linden T, Katschinski DM, Oehme F, Flamme I, Mukhopadhyay CK, et al. Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation. Blood 2005; 105:4613 - 9; http://dx.doi.org/10.1182/blood-2004-10-3980; PMID: 15741220
   PubMed Web of Science ®Google Scholar
• Gogvadze V, Zhivotovsky B, Orrenius S. The Warburg effect and mitochondrial stability in cancer cells. Mol Aspects Med 2010; 31:60 - 74; http://dx.doi.org/10.1016/j.mam.2009.12.004; PMID: 19995572
   PubMed Web of Science ®Google Scholar
• Prohaska JR. Impact of copper limitation on expression and function of multicopper oxidases (ferroxidases). Adv Nutr 2011; 2:89 - 95; http://dx.doi.org/10.3945/an.110.000208; PMID: 22332037
   PubMed Web of Science ®Google Scholar
• Zaitsev VN, Zaitseva I, Papiz M, Lindley PF. An X-ray crystallographic study of the binding sites of the azide inhibitor and organic substrates to ceruloplasmin, a multi-copper oxidase in the plasma. J Biol Inorg Chem 1999; 4:579 - 87; http://dx.doi.org/10.1007/s007750050380; PMID: 10550686
   PubMed Web of Science ®Google Scholar
• Harvey LJ, Ashton K, Hooper L, Casgrain A, Fairweather-Tait SJ. Methods of assessment of copper status in humans: a systematic review. Am J Clin Nutr 2009; 89:2009S - 24S; http://dx.doi.org/10.3945/ajcn.2009.27230E; PMID: 19420093
   PubMed Web of Science ®Google Scholar
• Cooper EH. [Plasma protein profile in neoplastic diseases]. Ric Clin Lab 1983; 13:Suppl 1 57 - 69; PMID: 6344180
   PubMedGoogle Scholar
• Vavilova TP, Gusarova IuN, Koroleva OV, Medvedev AE. [The role of ceruloplasmin in neoplastic processes]. Biomed Khim 2005; 51:263 - 75; PMID: 16104389
   PubMedGoogle Scholar
• Brewer GJ, Merajver SD. Cancer therapy with tetrathiomolybdate: antiangiogenesis by lowering body copper--a review. Integr Cancer Ther 2002; 1:327 - 37; http://dx.doi.org/10.1177/1534735402238185; PMID: 14664727
   PubMedGoogle Scholar
• Goodman VL, Brewer GJ, Merajver SD. Copper deficiency as an anti-cancer strategy. Endocr Relat Cancer 2004; 11:255 - 63; http://dx.doi.org/10.1677/erc.0.0110255; PMID: 15163301
   PubMed Web of Science ®Google Scholar
• Lowndes SA, Harris AL. Copper chelation as an antiangiogenic therapy. Oncol Res 2004; 14:529 - 39; PMID: 15666995
   PubMed Web of Science ®Google Scholar
• Fu S, Naing A, Fu C, Kuo MT, Kurzrock R. Overcoming platinum resistance through the use of a copper-lowering agent. Mol Cancer Ther 2012; 11:1221 - 5; http://dx.doi.org/10.1158/1535-7163.MCT-11-0864; PMID: 22491798
   PubMed Web of Science ®Google Scholar
• Trivedy CR, Warnakulasuriya KA, Peters TJ, Senkus R, Hazarey VK, Johnson NW. Raised tissue copper levels in oral submucous fibrosis. J Oral Pathol Med 2000; 29:241 - 8; http://dx.doi.org/10.1034/j.1600-0714.2000.290601.x; PMID: 10890553
   PubMed Web of Science ®Google Scholar
• Mondorf AW, Mackenrodt G, Halberstadt E. [Ceruloplasmin. I. Biochemistry of ceruloplasmin. II. Influence of estrogens on the ceruloplasmin content of the serum]. Klin Wochenschr 1971; 49:61 - 70; http://dx.doi.org/10.1007/BF01497302; PMID: 5543067
   PubMedGoogle Scholar
• Kluft C, Leuven JA, Helmerhorst FM, Krans HM. Pro-inflammatory effects of oestrogens during use of oral contraceptives and hormone replacement treatment. Vascul Pharmacol 2002; 39:149 - 54; http://dx.doi.org/10.1016/S1537-1891(02)00304-X; PMID: 12616983
   PubMed Web of Science ®Google Scholar
• Zatulovskiy EA, Skvortsov AN, Rusconi P, Ilyechova EY, Babich PS, Tsymbalenko NV, et al. Serum depletion of holo-ceruloplasmin induced by silver ions in vivo reduces uptake of cisplatin. J Inorg Biochem 2012; 116:88 - 96; http://dx.doi.org/10.1016/j.jinorgbio.2012.07.003; PMID: 23018271
   PubMed Web of Science ®Google Scholar
• Cabrera A, Alonzo E, Sauble E, Chu YL, Nguyen D, Linder MC, et al. Copper binding components of blood plasma and organs, and their responses to influx of large doses of (65)Cu, in the mouse. Biometals 2008; 21:525 - 43; http://dx.doi.org/10.1007/s10534-008-9139-6; PMID: 18357416
   PubMed Web of Science ®Google Scholar
• Yoshimura S, Tamaoki N, Ueyama Y, Hata J. Plasma protein production by human tumors xenotransplanted in nude mice. Cancer Res 1978; 38:3474 - 8; PMID: 688232
   PubMed Web of Science ®Google Scholar
• Patel BN, Dunn RJ, David S. Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain. J Biol Chem 2000; 275:4305 - 10; http://dx.doi.org/10.1074/jbc.275.6.4305; PMID: 10660599
   PubMed Web of Science ®Google Scholar
• Ilyechova E, Skvortsov A, Zatulovsky E, Tsymbalenko N, Shavlovsky M, Broggini M, et al. Experimental switching of copper status in laboratory rodents. J Trace Elem Med Biol 2011; 25:27 - 35; http://dx.doi.org/10.1016/j.jtemb.2010.08.002; PMID: 20965708
   PubMed Web of Science ®Google Scholar
• Kim BE, Turski ML, Nose Y, Casad M, Rockman HA, Thiele DJ. Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs. Cell Metab 2010; 11:353 - 63; http://dx.doi.org/10.1016/j.cmet.2010.04.003; PMID: 20444417
   PubMed Web of Science ®Google Scholar
• Holzer AK, Varki NM, Le QT, Gibson MA, Naredi P, Howell SB. Expression of the human copper influx transporter 1 in normal and malignant human tissues. J Histochem Cytochem 2006; 54:1041 - 9; http://dx.doi.org/10.1369/jhc.6A6970.2006; PMID: 16709730
   PubMed Web of Science ®Google Scholar
• Lee J, Petris MJ, Thiele DJ. Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system. J Biol Chem 2002; 277:40253 - 9; http://dx.doi.org/10.1074/jbc.M208002200; PMID: 12177073
   PubMed Web of Science ®Google Scholar
• Chandra RK. Nutrition and immunoregulation. Significance for host resistance to tumors and infectious diseases in humans and rodents. J Nutr 1992; 122:Suppl 754 - 7; PMID: 1542043
   PubMedGoogle Scholar
• Cursiefen C, Chen L, Borges LP, Jackson D, Cao J, Radziejewski C, et al. VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest 2004; 113:1040 - 50; PMID: 15057311
   PubMed Web of Science ®Google Scholar
• Dietrich WF, Lander ES, Smith JS, Moser AR, Gould KA, Luongo C, et al. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 1993; 75:631 - 9; http://dx.doi.org/10.1016/0092-8674(93)90484-8; PMID: 8242739
   PubMed Web of Science ®Google Scholar
• Oridate N, Lotan D, Xu X-C, Hong WK, Lotan R. Differential induction of apoptosis by all-trans-retinoic acid and N-(4-hydroxyphenyl)retinamide in human head and neck squamous cell carcinoma cell lines. Clin Cancer Res 1996; 2:855 - 63; PMID: 9816241
   PubMed Web of Science ®Google Scholar
• Hooper L, Ashton K, Harvey LJ, Decsi T, Fairweather-Tait SJ. Assessing potential biomarkers of micronutrient status by using a systematic review methodology: methods. Am J Clin Nutr 2009; 89:1953S - 9S; http://dx.doi.org/10.3945/ajcn.2009.27230A; PMID: 19403633
   PubMed Web of Science ®Google Scholar