751
Views
6
CrossRef citations to date
0
Altmetric
Research Paper

DNA and protein co-administration induces tolerogenic dendritic cells through DC-SIGN mediated negative signals

, , , , , & show all
Pages 2237-2245 | Received 27 Feb 2013, Accepted 11 May 2013, Published online: 04 Jun 2013

REFERENCE

  • Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004; 22:531 - 62; http://dx.doi.org/10.1146/annurev.immunol.21.120601.141122; PMID: 15032588
  • Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998; 188:287 - 96; http://dx.doi.org/10.1084/jem.188.2.287; PMID: 9670041
  • Gondek DC, Lu L-F, Quezada SA, Sakaguchi S, Noelle RJ. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol 2005; 174:1783 - 6; PMID: 15699103
  • Cao X, Cai SF, Fehniger TA, Song J, Collins LI, Piwnica-Worms DR, et al. Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance. Immunity 2007; 27:635 - 46; http://dx.doi.org/10.1016/j.immuni.2007.08.014; PMID: 17919943
  • Roncarolo M-G, Levings MK, Traversari C. Differentiation of T regulatory cells by immature dendritic cells. J Exp Med 2001; 193:F5 - 9; http://dx.doi.org/10.1084/jem.193.2.F5; PMID: 11208869
  • Cottrez F, Hurst SD, Coffman RL, Groux H. T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol 2000; 165:4848 - 53; PMID: 11046008
  • Jonuleit H, Schmitt E, Schuler G, Knop J, Enk AH. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 2000; 192:1213 - 22; http://dx.doi.org/10.1084/jem.192.9.1213; PMID: 11067871
  • Levings MK, Gregori S, Tresoldi E, Cazzaniga S, Bonini C, Roncarolo MG. Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood 2005; 105:1162 - 9; http://dx.doi.org/10.1182/blood-2004-03-1211; PMID: 15479730
  • Luo X, Tarbell KV, Yang H, Pothoven K, Bailey SL, Ding R, et al. Dendritic cells with TGF-β1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A 2007; 104:2821 - 6; http://dx.doi.org/10.1073/pnas.0611646104; PMID: 17307871
  • Ganesh BB, Cheatem DM, Sheng JR, Vasu C, Prabhakar BS. GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis. Int Immunol 2009; 21:269 - 82; http://dx.doi.org/10.1093/intimm/dxn147; PMID: 19174473
  • D’Ambrosio A, Colucci M, Pugliese O, Quintieri F, Boirivant M. Cholera toxin B subunit promotes the induction of regulatory T cells by preventing human dendritic cell maturation. J Leukoc Biol 2008; 84:661 - 8; http://dx.doi.org/10.1189/jlb.1207850; PMID: 18562485
  • Lavelle EC, McNeela E, Armstrong ME, Leavy O, Higgins SC, Mills KHG. Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation. J Immunol 2003; 171:2384 - 92; PMID: 12928385
  • Jin H, Kang Y, Zheng G, Xie Q, Xiao C, Zhang X, et al. Induction of active immune suppression by co-immunization with DNA- and protein-based vaccines. Virology 2005; 337:183 - 91; http://dx.doi.org/10.1016/j.virol.2005.03.029; PMID: 15914231
  • Kang Y, Jin H, Zheng G, Du X, Xiao C, Zhang X, et al. Co-inoculation of DNA and protein vaccines induces antigen-specific T cell suppression. Biochem Biophys Res Commun 2007; 353:1034 - 9; http://dx.doi.org/10.1016/j.bbrc.2006.12.124; PMID: 17204242
  • Li J, Jin H, Zhang F, Du X, Zhao G, Yu Y, et al. Treatment of autoimmune ovarian disease by co-administration with mouse zona pellucida protein 3 and DNA vaccine through induction of adaptive regulatory T cells. J Gene Med 2008; 10:810 - 20; http://dx.doi.org/10.1002/jgm.1200; PMID: 18452236
  • Jin H, Xiao C, Geng S, Hu Y, She R, Yu Y, et al. Protein/DNA vaccine-induced antigen-specific Treg confer protection against asthma. Eur J Immunol 2008; 38:2451 - 63; http://dx.doi.org/10.1002/eji.200737899; PMID: 18792401
  • Jin H, Kang Y, Zhao L, Xiao C, Hu Y, She R, et al. Induction of adaptive T regulatory cells that suppress the allergic response by coimmunization of DNA and protein vaccines. J Immunol 2008; 180:5360 - 72; PMID: 18390718
  • Li J, Geng S, Xie X, Liu H, Zheng G, Sun X, et al. Caveolin-1-mediated negative signaling plays a critical role in the induction of regulatory dendritic cells by DNA and protein coimmunization. J Immunol 2012; 189:2852 - 9; http://dx.doi.org/10.4049/jimmunol.1102828; PMID: 22904311
  • Smits HH, Engering A, van der Kleij D, de Jong EC, Schipper K, van Capel TM, et al. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immunol 2005; 115:1260 - 7; http://dx.doi.org/10.1016/j.jaci.2005.03.036; PMID: 15940144
  • Gringhuis SI, den Dunnen J, Litjens M, van Het Hof B, van Kooyk Y, Geijtenbeek TB. C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB. Immunity 2007; 26:605 - 16; http://dx.doi.org/10.1016/j.immuni.2007.03.012; PMID: 17462920
  • Peters PJ, Neefjes JJ, Oorschot V, Ploegh HL, Geuze HJ. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature 1991; 349:669 - 76; http://dx.doi.org/10.1038/349669a0; PMID: 1847504
  • Harding CV, Geuze HJ. Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells. J Cell Biol 1992; 119:531 - 42; http://dx.doi.org/10.1083/jcb.119.3.531; PMID: 1400590
  • Zimmer KP, Büning J, Weber P, Kaiserlian D, Strobel S. Modulation of antigen trafficking to MHC class II-positive late endosomes of enterocytes. Gastroenterology 2000; 118:128 - 37; http://dx.doi.org/10.1016/S0016-5085(00)70421-5; PMID: 10611161
  • Krug A, Rothenfusser S, Hornung V, Jahrsdörfer B, Blackwell S, Ballas ZK, et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur J Immunol 2001; 31:2154 - 63; http://dx.doi.org/10.1002/1521-4141(200107)31:7<2154::AID-IMMU2154>3.0.CO;2-U; PMID: 11449369
  • Levy DE, Marié I, Prakash A. Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity. Curr Opin Immunol 2003; 15:52 - 8; http://dx.doi.org/10.1016/S0952-7915(02)00011-0; PMID: 12495733
  • Geijtenbeek TB, Gringhuis SI. Signalling through C-type lectin receptors: shaping immune responses. Nat Rev Immunol 2009; 9:465 - 79; http://dx.doi.org/10.1038/nri2569; PMID: 19521399
  • McKenzie GJ, Khan M, Briend E, Stallwood Y, Champion BR. Notch: a unique therapeutic target for immunomodulation. Expert Opin Ther Targets 2005; 9:395 - 410; http://dx.doi.org/10.1517/14728222.9.2.395; PMID: 15934923
  • Knisz J, Banks A, McKeag L, Metcalfe DD, Rothman PB, Brown JM. Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation. Clin Immunol 2009; 132:277 - 84; http://dx.doi.org/10.1016/j.clim.2009.04.003; PMID: 19427817
  • Niedbala W, Cai B, Liew FY. Role of nitric oxide in the regulation of T cell functions. Ann Rheum Dis 2006; 65:Suppl 3 iii37 - 40; http://dx.doi.org/10.1136/ard.2006.058446; PMID: 17038470