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Gimap3

A foot-in-the-door to tissue-specific regulation of mitochondrial DNA genetics

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Pages 31-35 | Received 06 Dec 2010, Accepted 23 Jan 2011, Published online: 01 Jan 2011

References

  • Taylor RW, Turnbull DM. Mitochondrial DNA mutations in human disease. Nat Rev Genet 2005; 6:389 - 402
  • Wai T, Teoli D, Shoubridge EA. The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes. Nat Genet 2008; 40:1484 - 1488
  • Chinnery PF, Samuels DC. Relaxed replication of mtDNA: A model with implications for the expression of disease. Am J Hum Genet 1999; 64:1158 - 1165
  • Rahman S, Poulton J, Marchington D, Suomalainen A. Decrease of 3243 A→G mtDNA mutation from blood in MELAS syndrome: a longitudinal study. Am J Hum Genet 2001; 68:238 - 240
  • Rajasimha HK, Chinnery PF, Samuels DC. Selection against pathogenic mtDNA mutations in a stem cell population leads to the loss of the 3243A→G mutation in blood. Am J Hum Genet 2008; 82:333 - 343
  • Jenuth JP, Peterson AC, Shoubridge EA. Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice. Nat Genet 1997; 16:93 - 95
  • Battersby BJ, Loredo-Osti JC, Shoubridge EA. Nuclear genetic control of mitochondrial DNA segregation. Nat Genet 2003; 33:183 - 186
  • Jokinen R, Marttinen P, Sandell HK, Manninen T, Teerenhovi H, Wai T, et al. Gimap3 regulates tissue-specific mitochondrial DNA segregation. PLoS Genet 2010; 6:1001161
  • Krucken J, Schroetel RM, Muller IU, Saidani N, Marinovski P, Benten WP, et al. Comparative analysis of the human gimap gene cluster encoding a novel GTPase family. Gene 2004; 341:291 - 304
  • Nitta T, Nasreen M, Seike T, Goji A, Ohigashi I, Miyazaki T, et al. IAN family critically regulates survival and development of T lymphocytes. PLoS Biol 2006; 4:103
  • Hornum L, Romer J, Markholst H. The diabetesprone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1. Diabetes 2002; 51:1972 - 1979
  • Schulteis RD, Chu H, Dai X, Chen Y, Edwards B, Haribhai D, et al. Impaired survival of peripheral T cells, disrupted NK/NKT cell development and liver failure in mice lacking Gimap5. Blood 2008; 112:4905 - 4914
  • Barnes MJ, Aksoylar H, Krebs P, Bourdeau T, Arnold CN, Xia Y, et al. Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice. J Immunol 2010; 184:3743 - 3754
  • Veis DJ, Sentman CL, Bach EA, Korsmeyer SJ. Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes. J Immunol 1993; 151:2546 - 2554
  • Sandal T, Aumo L, Hedin L, Gjertsen BT, Doskeland SO. Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis. Mol Biol Cell 2003; 14:3292 - 3304
  • Wong VWYSA, Hutchings A, Pascall JC, Carter C, Bright N, Walker SA, et al. The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein. Self/Nonself 2010; 1:259 - 268
  • Schwefel D, Frohlich C, Eichhorst J, Wiesner B, Behlke J, Aravind L, et al. Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2). Proc Natl Acad Sci USA 2010; 107:20299 - 20304
  • Battersby BJ, Shoubridge EA. Selection of a mtDNA sequence variant in hepatocytes of heteroplasmic mice is not due to differences in respiratory chain function or efficiency of replication. Hum Mol Genet 2001; 10:2469 - 2479
  • Battersby BJ, Redpath ME, Shoubridge EA. Mitochondrial DNA segregation in hematopoietic lineages does not depend on MHC presentation of mitochondrially encoded peptides. Hum Mol Genet 2005; 14:2587 - 2594
  • Loveland B, Wang CR, Yonekawa H, Hermel E, Lindahl KF. Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein. Cell 1990; 60:971 - 980
  • Young L, Leonhard K, Tatsuta T, Trowsdale J, Langer T. Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science 2001; 291:2135 - 2138
  • Haynes CM, Yang Y, Blais SP, Neubert TA, Ron D. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Mol Cell 2010; 37:529 - 540
  • Ishikawa K, Toyama-Sorimachi N, Nakada K, Morimoto M, Imanishi H, Yoshizaki M, et al. The innate immune system in host mice targets cells with allogenic mitochondrial DNA. J Exp Med 2010; 207:2297 - 2305
  • Hoppins S, Lackner L, Nunnari J. The machines that divide and fuse mitochondria. Annu Rev Biochem 2007; 76:751 - 780
  • Campello S, Lacalle RA, Bettella M, Manes S, Scorrano L, Viola A. Orchestration of lymphocyte chemotaxis by mitochondrial dynamics. J Exp Med 2006; 203:2879 - 2886
  • Quintana A, Schwindling C, Wenning AS, Becherer U, Rettig J, Schwarz EC, et al. T cell activation requires mitochondrial translocation to the immunological synapse. Proc Natl Acad Sci USA 2007; 104:14418 - 14423
  • de Brito OM, Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008; 456:605 - 610
  • Wasiak S, Zunino R, McBride HM. Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death. J Cell Biol 2007; 177:439 - 450
  • Neuspiel M, Schauss AC, Braschi E, Zunino R, Rippstein P, Rachubinski RA, et al. Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Curr Biol 2008; 18:102 - 108
  • Renelli M, Matias V, Lo RY, Beveridge TJ. DNA-containing membrane vesicles of Pseudomonas aeruginosa PAO1 and their genetic transformation potential. Microbiology 2004; 150:2161 - 2169