Escorting Ras

References

• Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989; 49:4682 - 9; PMID: 2547513
   PubMed Web of Science ®Google Scholar
• Swarthout JT, Lobo S, Farh L, Croke MR, Greentree WK, Deschenes RJ, et al. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. J Biol Chem 2005; 280:31141 - 8; http://dx.doi.org/10.1074/jbc.M504113200; PMID: 16000296
   PubMed Web of Science ®Google Scholar
• Apolloni A, Prior IA, Lindsay M, Parton RG, Hancock JF. H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. Mol Cell Biol 2000; 20:2475 - 87; http://dx.doi.org/10.1128/MCB.20.7.2475-2487.2000; PMID: 10713171
   PubMed Web of Science ®Google Scholar
• Misaki R, Morimatsu M, Uemura T, Waguri S, Miyoshi E, Taniguchi N, et al. Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis. J Cell Biol 2010; 191:23 - 9; http://dx.doi.org/10.1083/jcb.200911143; PMID: 20876282
   PubMed Web of Science ®Google Scholar
• Ahearn IM, Haigis K, Bar-Sagi D, Philips MR. Regulating the regulator: post-translational modification of RAS. Nat Rev Mol Cell Biol 2012; 13:39 - 51; http://dx.doi.org/10.1038/nrm3255; PMID: 22189424
   PubMed Web of Science ®Google Scholar
• Duncan JA, Gilman AG. A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS). J Biol Chem 1998; 273:15830 - 7; http://dx.doi.org/10.1074/jbc.273.25.15830; PMID: 9624183
   PubMed Web of Science ®Google Scholar
• Goodwin JS, Drake KR, Rogers C, Wright L, Lippincott-Schwartz J, Philips MR, et al. Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway. J Cell Biol 2005; 170:261 - 72; http://dx.doi.org/10.1083/jcb.200502063; PMID: 16027222
   PubMed Web of Science ®Google Scholar
• Rocks O, Peyker A, Kahms M, Verveer PJ, Koerner C, Lumbierres M, et al. An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science 2005; 307:1746 - 52; http://dx.doi.org/10.1126/science.1105654; PMID: 15705808
   PubMed Web of Science ®Google Scholar
• Gomez GA, Daniotti JL. H-Ras dynamically interacts with recycling endosomes in CHO-K1 cells: involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment. J Biol Chem 2005; 280:34997 - 5010; http://dx.doi.org/10.1074/jbc.M506256200; PMID: 16079139
   PubMed Web of Science ®Google Scholar
• Platta HW, Stenmark H. Endocytosis and signaling. Curr Opin Cell Biol 2011; 23:393 - 403; http://dx.doi.org/10.1016/j.ceb.2011.03.008; PMID: 21474295
   PubMed Web of Science ®Google Scholar
• Han L, Wong D, Dhaka A, Afar D, White M, Xie W, et al. Protein binding and signaling properties of RIN1 suggest a unique effector function. Proc Natl Acad Sci U S A 1997; 94:4954 - 9; http://dx.doi.org/10.1073/pnas.94.10.4954; PMID: 9144171
   PubMed Web of Science ®Google Scholar
• Tall GG, Barbieri MA, Stahl PD, Horazdovsky BF. Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. Dev Cell 2001; 1:73 - 82; http://dx.doi.org/10.1016/S1534-5807(01)00008-9; PMID: 11703925
   PubMed Web of Science ®Google Scholar
• Jura N, Scotto-Lavino E, Sobczyk A, Bar-Sagi D. Differential modification of Ras proteins by ubiquitination. Mol Cell 2006; 21:679 - 87; http://dx.doi.org/10.1016/j.molcel.2006.02.011; PMID: 16507365
   PubMed Web of Science ®Google Scholar
• Xu L, Lubkov V, Taylor LJ, Bar-Sagi D. Feedback regulation of Ras signaling by Rabex-5-mediated ubiquitination. Curr Biol 2010; 20:1372 - 7; http://dx.doi.org/10.1016/j.cub.2010.06.051; PMID: 20655225
   PubMed Web of Science ®Google Scholar
• Yan H, Jahanshahi M, Horvath EA, Liu HY, Pfleger CM. Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila. Curr Biol 2010; 20:1378 - 82; http://dx.doi.org/10.1016/j.cub.2010.06.058; PMID: 20655224
   PubMed Web of Science ®Google Scholar
• Burke P, Schooler K, Wiley HS. Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking. Mol Biol Cell 2001; 12:1897 - 910; PMID: 11408594
   PubMed Web of Science ®Google Scholar
• Tsutsumi K, Fujioka Y, Tsuda M, Kawaguchi H, Ohba Y. Visualization of Ras-PI3K interaction in the endosome using BiFC. Cell Signal 2009; 21:1672 - 9; http://dx.doi.org/10.1016/j.cellsig.2009.07.004; PMID: 19616621
   PubMed Web of Science ®Google Scholar
• Cheng CM, Li H, Gasman S, Huang J, Schiff R, Chang EC. Compartmentalized Ras proteins transform NIH 3T3 cells with different efficiencies. Mol Cell Biol 2011; 31:983 - 97; http://dx.doi.org/10.1128/MCB.00137-10; PMID: 21189290
   PubMed Web of Science ®Google Scholar
• Hancock JF, Magee AI, Childs JE, Marshall CJ. All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 1989; 57:1167 - 77; http://dx.doi.org/10.1016/0092-8674(89)90054-8; PMID: 2661017
   PubMed Web of Science ®Google Scholar
• Chiu VK, Bivona T, Hach A, Sajous JB, Silletti J, Wiener H, et al. Ras signalling on the endoplasmic reticulum and the Golgi. Nat Cell Biol 2002; 4:343 - 50; PMID: 11988737
   PubMed Web of Science ®Google Scholar
• Perez de Castro I, Bivona TG, Philips MR, Pellicer A. Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus. Mol Cell Biol 2004; 24:3485 - 96; http://dx.doi.org/10.1128/MCB.24.8.3485-3496.2004; PMID: 15060167
   PubMed Web of Science ®Google Scholar
• Bivona TG, Quatela SE, Bodemann BO, Ahearn IM, Soskis MJ, Mor A, et al. PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis. Mol Cell 2006; 21:481 - 93; http://dx.doi.org/10.1016/j.molcel.2006.01.012; PMID: 16483930
   PubMed Web of Science ®Google Scholar
• Hu Y, Lu W, Chen G, Wang P, Chen Z, Zhou Y, et al. K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis. Cell Res 2012; 22:399 - 412; http://dx.doi.org/10.1038/cr.2011.145; PMID: 21876558
   PubMed Web of Science ®Google Scholar
• Chang EC, Barr M, Wang Y, Jung V, Xu HP, Wigler MH. Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell 1994; 79:131 - 41; http://dx.doi.org/10.1016/0092-8674(94)90406-5; PMID: 7923372
   PubMed Web of Science ®Google Scholar
• Onken B, Wiener H, Philips MR, Chang EC. Compartmentalized signaling of Ras in fission yeast. Proc Natl Acad Sci U S A 2006; 103:9045 - 50; http://dx.doi.org/10.1073/pnas.0603318103; PMID: 16754851
   PubMed Web of Science ®Google Scholar
• Chang EC, Philips MR. Spatial segregation of Ras signaling: new evidence from fission yeast. Cell Cycle 2006; 5:1936 - 9; http://dx.doi.org/10.4161/cc.5.17.3187; PMID: 16931912
   PubMed Web of Science ®Google Scholar
• Cheng CM, Chang EC. Busy traveling Ras. Cell Cycle 2011; 10:1180 - 1; http://dx.doi.org/10.4161/cc.10.8.15259; PMID: 21436618
   PubMed Web of Science ®Google Scholar
• Zheng ZY, Cheng CM, Fu XR, Chen LY, Xu L, Terrillon S, et al. CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling. Oncogene 2012; In press http://dx.doi.org/10.1038/onc.2011.607; PMID: 22231449
   PubMed Web of Science ®Google Scholar
• Kerppola TK. Bimolecular fluorescence complementation: visualization of molecular interactions in living cells. Methods Cell Biol 2008; 85:431 - 70; http://dx.doi.org/10.1016/S0091-679X(08)85019-4; PMID: 18155474
   PubMed Web of Science ®Google Scholar
• Raiborg C, Stenmark H. The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature 2009; 458:445 - 52; http://dx.doi.org/10.1038/nature07961; PMID: 19325624
   PubMed Web of Science ®Google Scholar
• Baldys A, Raymond JR. Critical role of ESCRT machinery in EGFR recycling. Biochemistry 2009; 48:9321 - 3; http://dx.doi.org/10.1021/bi900865u; PMID: 19673488
   PubMed Web of Science ®Google Scholar
• Lu A, Tebar F, Alvarez-Moya B, López-Alcalá C, Calvo M, Enrich C, et al. A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes. J Cell Biol 2009; 184:863 - 79; http://dx.doi.org/10.1083/jcb.200807186; PMID: 19289794
   PubMed Web of Science ®Google Scholar
• Sasaki AT, Carracedo A, Locasale JW, Anastasiou D, Takeuchi K, Kahoud ER, et al. Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors. Sci Signal 2011; 4:ra13; http://dx.doi.org/10.1126/scisignal.2001518; PMID: 21386094
   PubMed Web of Science ®Google Scholar
• Pylayeva-Gupta Y, Grabocka E, Bar-Sagi D. RAS oncogenes: weaving a tumorigenic web. Nat Rev Cancer 2011; 11:761 - 74; http://dx.doi.org/10.1038/nrc3106; PMID: 21993244
   PubMed Web of Science ®Google Scholar