Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection

References

• Centers for Disease Control and Prevention (CDC). HIV surveillance--United States, 1981-2008. MMWR Morb Mortal Wkly Rep 2011; 60:689 - 93; PMID: 21637182
   PubMedGoogle Scholar
• Walensky RP, Paltiel AD, Losina E, Mercincavage LM, Schackman BR, Sax PE, et al. The survival benefits of AIDS treatment in the United States. J Infect Dis 2006; 194:11 - 9; http://dx.doi.org/10.1086/505147; PMID: 16741877
   PubMed Web of Science ®Google Scholar
• Phillips AN, Neaton J, Lundgren JD. The role of HIV in serious diseases other than AIDS. AIDS 2008; 22:2409 - 18; http://dx.doi.org/10.1097/QAD.0b013e3283174636; PMID: 19005264
   PubMed Web of Science ®Google Scholar
• Lifson AR, Belloso WH, Carey C, Davey RT, Duprez D, El-Sadr WM, et al, INSIGHT Cause of Death Writing Group. Determination of the underlying cause of death in three multicenter international HIV clinical trials. HIV Clin Trials 2008; 9:177 - 85; http://dx.doi.org/10.1310/hct0903-177; PMID: 18547904
   PubMed Web of Science ®Google Scholar
• Deeks SG, Phillips AN. HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity. BMJ 2009; 338:a3172; http://dx.doi.org/10.1136/bmj.a3172; PMID: 19171560
   PubMed Web of Science ®Google Scholar
• Hasse B, Ledergerber B, Furrer H, Battegay M, Hirschel B, Cavassini M, et al, Swiss HIV Cohort Study. Morbidity and aging in HIV-infected persons: the Swiss HIV cohort study. Clin Infect Dis 2011; 53:1130 - 9; http://dx.doi.org/10.1093/cid/cir626; PMID: 21998280
   PubMed Web of Science ®Google Scholar
• Nixon DE, Landay AL. Biomarkers of immune dysfunction in HIV. Curr Opin HIV AIDS 2010; 5:498 - 503; http://dx.doi.org/10.1097/COH.0b013e32833ed6f4; PMID: 20978393
   PubMed Web of Science ®Google Scholar
• Dubé MP, Sattler FR. Inflammation and complications of HIV disease. J Infect Dis 2010; 201:1783 - 5; http://dx.doi.org/10.1086/652751; PMID: 20446849
   PubMed Web of Science ®Google Scholar
• Wolf K, Tsakiris DA, Weber R, Erb P, Battegay M, Swiss HIV Cohort Study. Antiretroviral therapy reduces markers of endothelial and coagulation activation in patients infected with human immunodeficiency virus type 1. J Infect Dis 2002; 185:456 - 62; http://dx.doi.org/10.1086/338572; PMID: 11865397
   PubMed Web of Science ®Google Scholar
• Kuller LH, Tracy R, Belloso W, De Wit S, Drummond F, Lane HC, et al, INSIGHT SMART Study Group. Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med 2008; 5:e203; http://dx.doi.org/10.1371/journal.pmed.0050203; PMID: 18942885
   PubMed Web of Science ®Google Scholar
• Grunfeld C, Delaney JA, Wanke C, Currier JS, Scherzer R, Biggs ML, et al. Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study. AIDS 2009; 23:1841 - 9; http://dx.doi.org/10.1097/QAD.0b013e32832d3b85; PMID: 19455012
   PubMed Web of Science ®Google Scholar
• Law MG, Friis-Møller N, El-Sadr WM, Weber R, Reiss P, D’Arminio Monforte A, et al, D:A:D Study Group. The use of the Framingham equation to predict myocardial infarctions in HIV-infected patients: comparison with observed events in the D:A:D Study. HIV Med 2006; 7:218 - 30; http://dx.doi.org/10.1111/j.1468-1293.2006.00362.x; PMID: 16630034
   PubMed Web of Science ®Google Scholar
• Fourie C, van Rooyen J, Pieters M, Conradie K, Hoekstra T, Schutte A. Is HIV-1 infection associated with endothelial dysfunction in a population of African ancestry in South Africa?. Cardiovasc J Afr 2011; 22:134 - 40; http://dx.doi.org/10.5830/CVJA-2010-056; PMID: 21713302
   PubMed Web of Science ®Google Scholar
• Armstrong EJ, Morrow DA, Sabatine MS. Inflammatory biomarkers in acute coronary syndromes: part I: introduction and cytokines. Circulation 2006; 113:e72 - 5; http://dx.doi.org/10.1161/CIRCULATIONAHA.105.595520; PMID: 16476853
   PubMed Web of Science ®Google Scholar
• Armstrong EJ, Morrow DA, Sabatine MS. Inflammatory biomarkers in acute coronary syndromes: part II: acute-phase reactants and biomarkers of endothelial cell activation. Circulation 2006; 113:e152 - 5; http://dx.doi.org/10.1161/CIRCULATIONAHA.105.595538; PMID: 16490825
   PubMedGoogle Scholar
• Armstrong EJ, Morrow DA, Sabatine MS. Inflammatory biomarkers in acute coronary syndromes: part III: biomarkers of oxidative stress and angiogenic growth factors. Circulation 2006; 113:e289 - 92; http://dx.doi.org/10.1161/CIRCULATIONAHA.105.595546; PMID: 16505179
   PubMedGoogle Scholar
• Calza L, Pocaterra D, Pavoni M, Colangeli V, Manfredi R, Verucchi G, et al. Plasma levels of VCAM-1, ICAM-1, E-Selectin, and P-Selectin in 99 HIV-positive patients versus 51 HIV-negative healthy controls. J Acquir Immune Defic Syndr 2009; 50:430 - 2; http://dx.doi.org/10.1097/QAI.0b013e31819a292c; PMID: 19322038
   PubMed Web of Science ®Google Scholar
• Gattegno L, Bentata-Peyssare M, Gronowski S, Chaouche K, Ferriere F. Elevated concentrations of circulating intercellular adhesion molecule 1 (ICAM-1) and of vascular cell adhesion molecule 1 (VCAM-1) in HIV-1 infection. Cell Adhes Commun 1995; 3:179 - 85; http://dx.doi.org/10.3109/15419069509081285; PMID: 8846020
   PubMed Web of Science ®Google Scholar
• Lichtner M, Cuomo MR, Rossi R, Strano S, Massetti AP, Mastroianni CM, et al. Increased carotid intima media thickness is associated with depletion of circulating myeloid dendritic cells in HIV-infected patients on suppressive antiretroviral treatment. Atherosclerosis 2009; 204:e1 - 3; http://dx.doi.org/10.1016/j.atherosclerosis.2008.12.025; PMID: 19185298
   PubMedGoogle Scholar
• Bernal E, Marín I, Muñoz A, Sabán J, Vicente-Vera T, Cano A. High prevalence of subclinical atherosclerotic disease in Spanish HIV-infected patients with low cardiovascular risk. AIDS Patient Care STDS 2011; 25:269 - 72; http://dx.doi.org/10.1089/apc.2011.0014; PMID: 21466379
   PubMed Web of Science ®Google Scholar
• Kline ER, Sutliff RL. The roles of HIV-1 proteins and antiretroviral drug therapy in HIV-1-associated endothelial dysfunction. J Investig Med 2008; 56:752 - 69; PMID: 18525451
   PubMed Web of Science ®Google Scholar
• Vlachopoulos C, Xaplanteris P, Sambatakou H, Mariolis E, Bratsas A, Christoforatou E, et al. Acute systemic inflammation induced by influenza A (H1N1) vaccination causes a deterioration in endothelial function in HIV-infected patients. HIV Med 2011; 12:594 - 601; http://dx.doi.org/10.1111/j.1468-1293.2011.00935.x; PMID: 21645196
   PubMed Web of Science ®Google Scholar
• Ucciferri C, Falasca K, Mancino P, Di Iorio A, Vecchiet J. Microalbuminuria and hypertension in HIV-infected patients: a preliminary study of telmisartan. Eur Rev Med Pharmacol Sci 2012; 16:491 - 8; PMID: 22696876
   PubMed Web of Science ®Google Scholar
• Hileman CO, Carman TL, Gripshover BM, O’Riordan M, Storer NJ, Harrill DE, et al. Salsalate is poorly tolerated and fails to improve endothelial function in virologically suppressed HIV-infected adults. AIDS 2010; 24:1958 - 61; http://dx.doi.org/10.1097/QAD.0b013e32833c3251; PMID: 20613460
   PubMed Web of Science ®Google Scholar
• Gupta SK, Johnson RM, Mather KJ, Clauss M, Rehman J, Saha C, et al. Anti-inflammatory treatment with pentoxifylline improves HIV-related endothelial dysfunction: a pilot study. AIDS 2010; 24:1377 - 80; http://dx.doi.org/10.1097/QAD.0b013e3283396024; PMID: 20559042
   PubMed Web of Science ®Google Scholar
• Tungsiripat M, El-Bejjani D, Rizk N, Dogra V, O’Riordan MA, Ross AC, et al. Carotid intima media thickness, inflammatory markers, and endothelial activation markers in HIV Patients with lipoatrophy increased at 48 weeks regardless of use of rosiglitazone or placebo. AIDS Res Hum Retroviruses 2011; 27:295 - 302; http://dx.doi.org/10.1089/aid.2010.0187; PMID: 20969457
   PubMed Web of Science ®Google Scholar
• van Vonderen MG, Hassink EA, van Agtmael MA, Stehouwer CD, Danner SA, Reiss P, et al. Increase in carotid artery intima-media thickness and arterial stiffness but improvement in several markers of endothelial function after initiation of antiretroviral therapy. J Infect Dis 2009; 199:1186 - 94; http://dx.doi.org/10.1086/597475; PMID: 19275490
   PubMed Web of Science ®Google Scholar
• Rodger AJ, Fox Z, Lundgren JD, Kuller LH, Boesecke C, Gey D, et al, INSIGHT Strategies for Management of Antiretroviral Therapy (SMART) Study Group. Activation and coagulation biomarkers are independent predictors of the development of opportunistic disease in patients with HIV infection. J Infect Dis 2009; 200:973 - 83; http://dx.doi.org/10.1086/605447; PMID: 19678756
   PubMed Web of Science ®Google Scholar
• Ford ES, Greenwald JH, Richterman AG, Rupert A, Dutcher L, Badralmaa Y, et al. Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection. AIDS 2010; 24:1509 - 17; http://dx.doi.org/10.1097/QAD.0b013e32833ad914; PMID: 20505494
   PubMed Web of Science ®Google Scholar
• Musselwhite LW, Sheikh V, Norton TD, Rupert A, Porter BO, Penzak SR, et al. Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV. AIDS 2011; 25:787 - 95; http://dx.doi.org/10.1097/QAD.0b013e3283453fcb; PMID: 21412059
   PubMed Web of Science ®Google Scholar
• Sipsas NV, Sfikakis PP, Touloumi G, Pantazis N, Choremi H, Kordossis T. Elevated serum levels of soluble immune activation markers are associated with increased risk for death in HAART-naive HIV-1-infected patients. AIDS Patient Care STDS 2003; 17:147 - 53; http://dx.doi.org/10.1089/108729103321619755; PMID: 12737638
   PubMed Web of Science ®Google Scholar
• Francisci D, Falcinelli E, Belfiori B, Petito E, Fierro T, Baldelli F, et al. Impact of tenofovir versus abacavir on HIV-related endothelial dysfunction. AIDS Patient Care STDS 2011; 25:567 - 9; http://dx.doi.org/10.1089/apc.2011.0184; PMID: 21851265
   PubMed Web of Science ®Google Scholar
• Jong E, Louw S, van Gorp EC, Meijers JC, ten Cate H, Jacobson BF. The effect of initiating combined antiretroviral therapy on endothelial cell activation and coagulation markers in South African HIV-infected individuals. Thromb Haemost 2010; 104:1228 - 34; http://dx.doi.org/10.1160/TH10-04-0233; PMID: 20886182
   PubMed Web of Science ®Google Scholar
• Aukrust P, Bjørnsen S, Lunden B, Otterdal K, Ng EC, Ameln W, et al. Persistently elevated levels of von Willebrand factor antigen in HIV infection. Downregulation during highly active antiretroviral therapy. Thromb Haemost 2000; 84:183 - 7; PMID: 10959687
   PubMed Web of Science ®Google Scholar
• Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, et al, VACS Project Team. Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV?. Clin Infect Dis 2012; 54:984 - 94; http://dx.doi.org/10.1093/cid/cir989; PMID: 22337823
   PubMed Web of Science ®Google Scholar
• Schved JF, Gris JC, Arnaud A, Martinez P, Sanchez N, Wautier JL, et al. von Willebrand factor antigen, tissue-type plasminogen activator antigen, and risk of death in human immunodeficiency virus 1-related clinical disease: independent prognostic relevance of tissue-type plasminogen activator. J Lab Clin Med 1992; 120:411 - 9; PMID: 1517688
   PubMedGoogle Scholar
• Gresele P, Falcinelli E, Sebastiano M, Baldelli F. Endothelial and platelet function alterations in HIV-infected patients. Thromb Res 2012; 129:301 - 8; http://dx.doi.org/10.1016/j.thromres.2011.11.022; PMID: 22192157
   PubMed Web of Science ®Google Scholar
• Rectenwald JE, Myers DD Jr., Hawley AE, Longo C, Henke PK, Guire KE, et al. D-dimer, P-selectin, and microparticles: novel markers to predict deep venous thrombosis. A pilot study. Thromb Haemost 2005; 94:1312 - 7; PMID: 16411411
   PubMed Web of Science ®Google Scholar
• Suy A, Martínez E, Coll O, Lonca M, Palacio M, de Lazzari E, et al. Increased risk of pre-eclampsia and fetal death in HIV-infected pregnant women receiving highly active antiretroviral therapy. AIDS 2006; 20:59 - 66; http://dx.doi.org/10.1097/01.aids.0000198090.70325.bd; PMID: 16327320
   PubMed Web of Science ®Google Scholar
• Graham SM, Rajwans N, Jaoko W, et al. Endothelial activation biomarkers increase after HIV-1 acquisition: plasma VCAM-1 predicts disease progression. AIDS 2013; In press
   Web of Science ®Google Scholar
• Graham SM, Rajwans N, Tapia KA, Jaoko W, Estambale BB, McClelland RS. A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiviral therapy. BMC Infect Dis 2013; 13:263; http://dx.doi.org/10.1186/1471-2334-13-263; PMID: 23734875
   PubMed Web of Science ®Google Scholar
• Ozturk B, Tutuncu E, Kuscu F, Gurbuz Y, Sencan I, Tuzun H. Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions. Int J Infect Dis 2012; 16:e89 - 93; http://dx.doi.org/10.1016/j.ijid.2011.06.005; PMID: 22154082
   PubMed Web of Science ®Google Scholar
• Zangerle R, Fuchs D, Sarcletti M, Gallati H, Reibnegger G, Wachter H, et al. Increased concentrations of soluble tumor necrosis factor receptor 75 but not of soluble intercellular adhesion molecule-1 are associated with the decline of CD4+ lymphocytes in HIV infection. Clin Immunol Immunopathol 1994; 72:328 - 34; http://dx.doi.org/10.1006/clin.1994.1149; PMID: 7914841
   PubMedGoogle Scholar
• Greenwood AJ, Hughes J, Wallace G, Seed P, Stanford MR, Graham EM. Soluble intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) in patients with HIV/AIDS does not appear to correlate with cytomegalovirus retinitis. Int J STD AIDS 1998; 9:713 - 4; PMID: 9863589
   PubMed Web of Science ®Google Scholar
• Renwick N, Weverling GJ, Brouwer J, Bakker M, Schulz TF, Goudsmit J. Vascular endothelial growth factor levels in serum do not increase following HIV type 1 and HHV8 seroconversion and lack correlation with AIDS-related Kaposi’s sarcoma. AIDS Res Hum Retroviruses 2002; 18:695 - 8; http://dx.doi.org/10.1089/088922202760072302; PMID: 12167275
   PubMed Web of Science ®Google Scholar
• Hsue PY, Lo JC, Franklin A, Bolger AF, Martin JN, Deeks SG, et al. Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection. Circulation 2004; 109:1603 - 8; http://dx.doi.org/10.1161/01.CIR.0000124480.32233.8A; PMID: 15023877
   PubMed Web of Science ®Google Scholar
• El-Sadr WM, Lundgren J, Neaton JD, Gordin F, Abrams D, Arduino RC, et al, Strategies for Management of Antiretroviral Therapy (SMART) Study Group. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med 2006; 355:2283 - 96; http://dx.doi.org/10.1056/NEJMoa062360; PMID: 17135583
   PubMed Web of Science ®Google Scholar