Species-dependent hepatic and intestinal metabolism of selective oestrogen receptor degrader LSZ102 by sulphation and glucuronidation

David Pearsona Novartis Institutes for Biomedical Research, Basel, Switzerland; Correspondence[email protected]

Yi Jina Novartis Institutes for Biomedical Research, Basel, Switzerland;

Andrea Romeoa Novartis Institutes for Biomedical Research, Basel, Switzerland;

Bertrand-Luc Birlingera Novartis Institutes for Biomedical Research, Basel, Switzerland;

Hilmar Schillera Novartis Institutes for Biomedical Research, Basel, Switzerland;

Yan Jib Novartis Institutes for Biomedical Research, East Hanover, NJ, USA;

Mithat Gunduzc Novartis Institutes for Biomedical Research, Cambridge, MA, USA

Daniela Baldonia Novartis Institutes for Biomedical Research, Basel, Switzerland;

Markus Wallesa Novartis Institutes for Biomedical Research, Basel, Switzerland;

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