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mAbs Volume 10, 2018 - Issue 1
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Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics

Nicole M. Piche-NicholasBioMedicine Design, Pfizer Inc., Cambridge, MA, USACorrespondence[email protected]
,
Lindsay B. AveryBioMedicine Design, Pfizer Inc., Andover, MA, USA
,
Amy C. KingBioMedicine Design, Pfizer Inc., Cambridge, MA, USA
,
Mania KavosiBioMedicine Design, Pfizer Inc., Andover, MA, USA
,
Mengmeng WangBioMedicine Design, Pfizer Inc., Andover, MA, USA
,
Denise M. O'HaraBioMedicine Design, Pfizer Inc., Andover, MA, USA
,
Lioudmila TchistiakovaBioMedicine Design, Pfizer Inc., Cambridge, MA, USA
&
Madan KatragaddaBioMedicine Design, Pfizer Inc., Cambridge, MA, USACorrespondence[email protected]
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Pages 81-94 | Received 16 Jan 2015, Accepted 02 Oct 2017, Published online: 03 Nov 2017

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The Neonatal Fc Receptor (FcRn): A Misnomer?
Source: Frontiers Media SA

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