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Dissecting the molecular basis of high viscosity of monospecific and bispecific IgG antibodies
Cholpon Tilegenovaa Antibody Engineering, Genentech Inc., South San Francisco, CA, USA
https://orcid.org/0000-0002-8618-0270
Saeed Izadib Early Stage Pharmaceutical Development, Genentech Inc., South San Francisco, CA, USA
https://orcid.org/0000-0003-4206-8559
Jianping Yinc Structural Biology, Genentech Inc., South San Francisco, CA, USA
https://orcid.org/0000-0003-0425-5804
Christine S. Huangd Protein Chemistry, Genentech Inc., South San Francisco, CA, USA
https://orcid.org/0000-0003-4082-3880
Jiansheng Wud Protein Chemistry, Genentech Inc., South San Francisco, CA, USA
, Diego Ellermand Protein Chemistry, Genentech Inc., South San Francisco, CA, USA
, Sarah G. Hymowitzc Structural Biology, Genentech Inc., South San Francisco, CA, USA
https://orcid.org/0000-0003-4743-4386
Benjamin Walterse Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA, USA
https://orcid.org/0000-0001-5400-0696
Cleo Salisburyb Early Stage Pharmaceutical Development, Genentech Inc., South San Francisco, CA, USA
& Paul J. Cartera Antibody Engineering, Genentech Inc., South San Francisco, CA, USACorrespondence[email protected]
https://orcid.org/0000-0001-7854-062X
Article: 1692764
|
Received 05 Aug 2019, Accepted 11 Nov 2019, Published online: 28 Nov 2019
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