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Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX
Joey G. Sheffa Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, CanadaCorrespondence[email protected]
https://orcid.org/0000-0002-9269-6863View further author information
, https://orcid.org/0000-0002-9269-6863View further author information
John F. Kellya Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, CanadaView further author information
, Anna Robothama Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, CanadaView further author information
, Traian Suleab Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canadahttps://orcid.org/0000-0001-5301-8261View further author information
, Félix Malenfantb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Denis L’Abbéb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Mélanie Duchesneb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Alex Pelletierb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Jean Lefebvreb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Andrea Acelb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Marie Paratb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canadahttps://orcid.org/0000-0003-4835-4345View further author information
, Mylene Gosselinb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Cunle Wub Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Yves Fortinb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, CanadaView further author information
, Jason Baardsnesb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canadahttps://orcid.org/0000-0001-5587-3034View further author information
, Henk Van Faassena Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, CanadaView further author information
, Shannon Awreyc Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canadahttps://orcid.org/0000-0001-9905-6853View further author information
, Shawn C. Chafec Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canadahttps://orcid.org/0000-0001-8802-651XView further author information
, Paul C. McDonaldc Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canadahttps://orcid.org/0000-0002-7238-2912View further author information
, Shoukat Dedharc Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canada;d Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canadahttps://orcid.org/0000-0003-4355-1657View further author information
& Anne E.G. Lenferinkb Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canadahttps://orcid.org/0000-0001-9825-281XView further author information
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Article: 1997072
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Received 05 Jul 2021, Accepted 20 Oct 2021, Published online: 23 Nov 2021
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