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Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities
Desislava Yanakievaa Institute for Organic Chemistry and Biochemistry, Technische Universität Darmstadt, Darmstadt, Germany;b Protein Engineering and Antibody Technologies, Protein Engineering and Antibody Technologies, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Lukas Pekarb Protein Engineering and Antibody Technologies, Protein Engineering and Antibody Technologies, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Andreas Eversb Protein Engineering and Antibody Technologies, Protein Engineering and Antibody Technologies, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Markus Fleischerc Protein and Cell Sciences, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Stephan Kellerc Protein and Cell Sciences, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Dirk Mueller-Pompallac Protein and Cell Sciences, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Lars Toleikisb Protein Engineering and Antibody Technologies, Protein Engineering and Antibody Technologies, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Harald Kolmara Institute for Organic Chemistry and Biochemistry, Technische Universität Darmstadt, Darmstadt, GermanyView further author information
, Stefan Zielonkab Protein Engineering and Antibody Technologies, Protein Engineering and Antibody Technologies, Merck Healthcare KGaA, Darmstadt, GermanyCorrespondence[email protected] [email protected]
View further author information
& View further author information
Simon Krahb Protein Engineering and Antibody Technologies, Protein Engineering and Antibody Technologies, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Article: 2018960
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Received 01 Oct 2021, Accepted 13 Dec 2021, Published online: 11 Jan 2022
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