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Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα /gp130 hexameric signaling complex formation
Chun-Chi Choua Department of Obstetrics & Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, TaiwanView further author information
, Kuo-Tai Huab Graduate Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, TaiwanView further author information
, Min-Wei Chena Department of Obstetrics & Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, TaiwanView further author information
, Chin-Jui Wua Department of Obstetrics & Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, TaiwanView further author information
, Chun-Hua Hsuc Department of Agricultural Chemistry, National Taiwan University, Taipei, TaiwanView further author information
, Jann-Tay Wangd Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University, Hospital, Taipei, Taiwan
https://orcid.org/0000-0002-0924-3469View further author information
Michael Hsiaoe The Genomics Research Center, Academia Sinica, Taipei, TaiwanView further author information
& Lin-Hung Weia Department of Obstetrics & Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, TaiwanCorrespondence[email protected]
View further author information
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Article: 2029675
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Received 27 Jul 2021, Accepted 12 Jan 2022, Published online: 08 Feb 2022
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