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Research Article

Possible data-generating models of longitudinal continuous outcomes and intercurrent events to investigate estimands

Marian Mitroiua Methodology Working Group, Medicines Evaluation Board, The Netherlands;b Clinical Trial Methodology Department, Biostatistics and Research Support, Julius Center for Health Sciences and Primary Care, Biostatistics and Research Support, University Medical Center Utrecht, Utrecht University, The NetherlandsCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-6479-4757
ORCID Icon,
Steven Teerenstraa Methodology Working Group, Medicines Evaluation Board, The Netherlands;c Department for Health Evidence, section Biostatistics, Radboud University Medical Center, The Netherlands
,
Katrien Oude Rengerinka Methodology Working Group, Medicines Evaluation Board, The Netherlands;b Clinical Trial Methodology Department, Biostatistics and Research Support, Julius Center for Health Sciences and Primary Care, Biostatistics and Research Support, University Medical Center Utrecht, Utrecht University, The Netherlands
,
Frank Pétavyd Data Analytics and Methods Taskforce, European Medicines Agency, The Netherlands
&
Kit CB Roesa Methodology Working Group, Medicines Evaluation Board, The Netherlands;c Department for Health Evidence, section Biostatistics, Radboud University Medical Center, The Netherlands
Received 10 Oct 2023, Accepted 11 Jun 2024, Accepted author version posted online: 26 Jun 2024
Accepted author version

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