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Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1
Julie A DouthwaiteMedImmune Ltd.; Cambridge, UKCorrespondence[email protected]
, Sudharsan SridharanMedImmune Ltd.; Cambridge, UK
, Catherine HuntingtonMedImmune Ltd.; Cambridge, UK
, Jayne HammersleyMedImmune Ltd.; Cambridge, UK
, Rose MarwoodMedImmune Ltd.; Cambridge, UK
, Jonna K HakulinenDiscovery Sciences; Structure, Biophysics and Computational Sciences; AstraZeneca R&D; Mölndal, Sweden
, Margareta EkDiscovery Sciences; Structure, Biophysics and Computational Sciences; AstraZeneca R&D; Mölndal, Sweden
, Tove SjögrenDiscovery Sciences; Structure, Biophysics and Computational Sciences; AstraZeneca R&D; Mölndal, Sweden
, David RiderEmployees of MedImmune Ltd. at the time the work was undertaken
, Cyril PrivezentzevEmployees of MedImmune Ltd. at the time the work was undertaken
, Jonathan C SeamanMedImmune Ltd.; Cambridge, UK
, Peter CariukMedImmune Ltd.; Cambridge, UK
, Vikki KnightsEmployees of MedImmune Ltd. at the time the work was undertaken
, Joyce YoungEmployees of MedImmune Ltd. at the time the work was undertaken
, Trevor WilkinsonMedImmune Ltd.; Cambridge, UK
, Matthew SleemanMedImmune Ltd.; Cambridge, UK
, Donna K FinchMedImmune Ltd.; Cambridge, UK
, David C LoweMedImmune Ltd.; Cambridge, UK
& Tristan J VaughanMedImmune Ltd.; Cambridge, UK
show all
Pages 152-166
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Received 08 Aug 2014, Accepted 02 Nov 2014, Published online: 14 Jan 2015
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