Drug Development and Industrial Pharmacy, Volume 42, Issue 3 (2016)

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Drug Development and Industrial Pharmacy, Volume 42, Issue 3 (2016)

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Recent advances in solid dispersions and the formulation of poorly absorbed drugs.

Editorial

Editorial
Recent advances in solid dispersions and the formulation of poorly absorbed drugs
Hugh D. C. Smyth
Pages: 351-352
Published online: 29 Jan 2016
CitationforRecent advances in solid dispersions and the formulation of poorly absorbed drugs | Full Text | References | PDF (118.2 KB)
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Free Access

Research Article

Article
A pre-formulation study of a polymeric solid dispersion of paclitaxel prepared using a quasi-emulsion solvent diffusion method to improve the oral bioavailability in rats
Hongze Piao, Liang Yang, Hongyu Piao, Peixiang Wang, Huihui Shi, Liang Fang & Fude Cui
Pages: 353-363
Published online: 10 Jul 2015
AbstractforA pre-formulation study of a polymeric solid dispersion of paclitaxel prepared using a quasi-emulsion solvent diffusion method to improve the oral bioavailability in rats | Full Text | References | PDF (1.1 MB)
  • 375 Views
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Article
A study on the solid state characteristics of spray-congealed glyceryl dibehenate solid lipid microparticles containing ibuprofen
Priscilla Chui Hong Wong, Paul Wan Sia Heng & Lai Wah Chan
Pages: 364-377
Published online: 16 Jun 2015
AbstractforA study on the solid state characteristics of spray-congealed glyceryl dibehenate solid lipid microparticles containing ibuprofen | Full Text | References | PDF (2.7 MB) | Supplemental
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Article
Towards improved solubility of poorly water-soluble drugs: cryogenic co-grinding of piroxicam with carrier polymers
Anna Penkina, Kristian Semjonov, Maija Hakola, Sirpa Vuorinen, Timo Repo, Jouko Yliruusi, Jaan Aruväli, Karin Kogermann, Peep Veski & Jyrki Heinämäki
Pages: 378-388
Published online: 11 Jun 2015
AbstractforTowards improved solubility of poorly water-soluble drugs: cryogenic co-grinding of piroxicam with carrier polymers | Full Text | References | PDF (1.9 MB)
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Article
Combined application of mixture experimental design and artificial neural networks in the solid dispersion development
Djordje P. Medarević, Peter Kleinebudde, Jelena Djuriš, Zorica Djurić & Svetlana Ibrić
Pages: 389-402
Published online: 11 Jun 2015
AbstractforCombined application of mixture experimental design and artificial neural networks in the solid dispersion development | Full Text | References | PDF (5 MB)
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Article
Impact of HPMC on the physical properties of spray-congealed PEG microparticles and its swelling effect on rifampicin dissolution
Ching Mien Oh, Carin Ru Shan Siow, Paul Wan Sia Heng & Lai Wah Chan
Pages: 403-411
Published online: 13 Jul 2015
AbstractforImpact of HPMC on the physical properties of spray-congealed PEG microparticles and its swelling effect on rifampicin dissolution | Full Text | References | PDF (1.4 MB)
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Article
A silica-supported solid dispersion of bifendate using supercritical carbon dioxide method with enhanced dissolution rate and oral bioavailability
Cuifang Cai, Muhua Liu, Yun Li, Bei Guo, Hui Chang, Xiangrong Zhang, Xiaoxu Yang & Tianhong Zhang
Pages: 412-417
Published online: 29 Jul 2015
AbstractforA silica-supported solid dispersion of bifendate using supercritical carbon dioxide method with enhanced dissolution rate and oral bioavailability | Full Text | References | PDF (905 KB)
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Article
Potential interaction between zinc ions and a cyclodextrin-based diclofenac formulation
Imad I. Hamdan, Dina El-Sabawi & Mariam Abdel Jalil
Pages: 418-428
Published online: 07 Aug 2015
AbstractforPotential interaction between zinc ions and a cyclodextrin-based diclofenac formulation | Full Text | References | PDF (1.4 MB)
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Article
Effect of hydrophilic additives on the dissolution and pharmacokinetic properties of itraconazole-enteric polymer hot-melt extruded amorphous solid dispersions
Bo Lang, Sha Liu, James W. McGinity & Robert O. Williams III
Pages: 429-445
Published online: 10 Sep 2015
AbstractforEffect of hydrophilic additives on the dissolution and pharmacokinetic properties of itraconazole-enteric polymer hot-melt extruded amorphous solid dispersions | Full Text | References | PDF (1.9 MB)
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Article
Use of the Flory–Huggins theory to predict the solubility of nifedipine and sulfamethoxazole in the triblock, graft copolymer Soluplus
Mohammad A. Altamimi & Steven H. Neau
Pages: 446-455
Published online: 12 Aug 2015
AbstractforUse of the Flory–Huggins theory to predict the solubility of nifedipine and sulfamethoxazole in the triblock, graft copolymer Soluplus | Full Text | References | PDF (962.1 KB)
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Article
Development and evaluation of alginate-chitosan gastric floating beads loading with oxymatrine solid dispersion
Yanhua Liu, Lihong Chen, Chengming Zhou, Jianhong Yang, Yanhui Hou & Wenping Wang
Pages: 456-463
Published online: 30 Sep 2015
AbstractforDevelopment and evaluation of alginate-chitosan gastric floating beads loading with oxymatrine solid dispersion | Full Text | References | PDF (1.3 MB)
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Article
Effect of pore size of three-dimensionally ordered macroporous chitosan–silica matrix on solubility, drug release, and oral bioavailability of loaded-nimodipine
Yikun Gao, Yuling Xie, Hongrui Sun, Qinfu Zhao, Xin Zheng, Siling Wang & Tongying Jiang
Pages: 464-472
Published online: 27 Oct 2015
AbstractforEffect of pore size of three-dimensionally ordered macroporous chitosan–silica matrix on solubility, drug release, and oral bioavailability of loaded-nimodipine | Full Text | References | PDF (1.8 MB)
  • 219 Views
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Article
Development, optimization and in vivo characterization of domperidone-controlled release hot-melt-extruded films for buccal delivery
Chinna Reddy Palem, Narendar Reddy Dudhipala, Sunil Kumar Battu, Michael A. Repka & Madhusudan Rao Yamsani
Pages: 473-484
Published online: 04 Nov 2015
AbstractforDevelopment, optimization and in vivo characterization of domperidone-controlled release hot-melt-extruded films for buccal delivery | Full Text | References | PDF (1.6 MB)
  • 410 Views
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Article
Solid-state characterization of Felodipine–Soluplus amorphous solid dispersions
Jiannan Lu, Kristina Cuellar, Nathan I. Hammer, Seongbong Jo, Andreas Gryczke, Karl Kolter, Nigel Langley & Michael A. Repka
Pages: 485-496
Published online: 04 Nov 2015
AbstractforSolid-state characterization of Felodipine–Soluplus amorphous solid dispersions | Full Text | References | PDF (1.7 MB)
  • 873 Views
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Article
Formulation, physicochemical characterization and in-vivo evaluation of ion-sensitive metformin loaded-biopolymeric beads
Ahmed N. Allam & Mohammed M. Mehanna
Pages: 497-505
Published online: 26 Jun 2015
AbstractforFormulation, physicochemical characterization and in-vivo evaluation of ion-sensitive metformin loaded-biopolymeric beads | Full Text | References | PDF (1.1 MB)
  • 176 Views
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Article
Enhanced oral bioavailability of felodipine by novel solid self-microemulsifying tablets
Boyu Jing, Zhiyuan Wang, Rui Yang, Xia Zheng, Jia Zhao, Si Tang & Zhonggui He
Pages: 506-512
Published online: 15 Jul 2015
AbstractforEnhanced oral bioavailability of felodipine by novel solid self-microemulsifying tablets | Full Text | References | PDF (528 KB)
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