Drug Development and Industrial Pharmacy, Volume 43, Issue 3 (2017)

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Drug Development and Industrial Pharmacy, Volume 43, Issue 3 (2017)

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Review Article

Review Article
The long and winding road to inhaled TB therapy: not only the bug’s fault
Stefano Giovagnoli, Aurelie Schoubben & Maurizio Ricci
Pages: 347-363
Published online: 05 Jan 2017
AbstractforThe long and winding road to inhaled TB therapy: not only the bug’s fault | Full Text | References | PDF (2.5 MB)
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Research Articles

Article
Implementation of design of experiments approach for the micronization of a drug with a high brittle–ductile transition particle diameter
Ashkan K. Yazdi & Hugh D. C. Smyth
Pages: 364-371
Published online: 14 Nov 2016
AbstractforImplementation of design of experiments approach for the micronization of a drug with a high brittle–ductile transition particle diameter | Full Text | References | PDF (1.7 MB)
  • 219 Views
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Article
Solvents effects on crystallinity and dissolution of β-artemether
Jianghui Xu, Vikramjeet Singh, Xianzhen Yin, Parbeen Singh, Li Wu, Xiaonan Xu, Tao Guo, Lixin Sun, Shuangying Gui & Jiwen Zhang
Pages: 372-378
Published online: 14 Nov 2016
AbstractforSolvents effects on crystallinity and dissolution of β-artemether | Full Text | References | PDF (1.6 MB) | Supplemental
  • 246 Views
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Article
The interprocess NIR sampling as an alternative approach to multivariate statistical process control for identifying sources of product-quality variability
Snežana Marković, Janez Kerč & Matej Horvat
Pages: 379-389
Published online: 11 Nov 2016
AbstractforThe interprocess NIR sampling as an alternative approach to multivariate statistical process control for identifying sources of product-quality variability | Full Text | References | PDF (2.2 MB)
  • 207 Views
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Article
In vitro and in vivo evaluation of paclitaxel–lapatinib-loaded F127 pluronic micelles
Pouya Dehghankelishadi, Ebrahim Saadat, Fatemeh Ravar, Maliheh Safavi, Mahboobeh Pordeli, Mehdi Gholami & Farid Abedin Dorkoosh
Pages: 390-398
Published online: 14 Nov 2016
AbstractforIn vitro and in vivo evaluation of paclitaxel–lapatinib-loaded F127 pluronic micelles | Full Text | References | PDF (1.5 MB)
  • 312 Views
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Article
Thermosensitive bioadhesive gels for the vaginal delivery of sildenafil citrate: in vitro characterization and clinical evaluation in women using clomiphene citrate for induction of ovulation
Ghareb M. Soliman, Gihan Fetih & Ahmed M. Abbas
Pages: 399-408
Published online: 14 Nov 2016
AbstractforThermosensitive bioadhesive gels for the vaginal delivery of sildenafil citrate: in vitro characterization and clinical evaluation in women using clomiphene citrate for induction of ovulation | Full Text | References | PDF (1.1 MB)
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Article
Evaluation of superabsorbent linseed-polysaccharides as a novel stimuli-responsive oral sustained release drug delivery system
Muhammad Tahir Haseeb, Muhammad Ajaz Hussain, Sajid Bashir, Muhammad Umer Ashraf & Naveed Ahmad
Pages: 409-420
Published online: 28 Nov 2016
AbstractforEvaluation of superabsorbent linseed-polysaccharides as a novel stimuli-responsive oral sustained release drug delivery system | Full Text | References | PDF (2.7 MB) | Supplemental
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Article
The preparation and evaluation of salt forms of linogliride with reduced solubilities as candidates for extended release
Frank A. Chrzanowski & Kaleem Ahmad
Pages: 421-431
Published online: 21 Nov 2016
AbstractforThe preparation and evaluation of salt forms of linogliride with reduced solubilities as candidates for extended release | Full Text | References | PDF (1.1 MB)
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Article
Mucoadhesive nanostructured lipid carriers (NLCs) as potential carriers for improving oral delivery of curcumin
Sanipon Chanburee & Waree Tiyaboonchai
Pages: 432-440
Published online: 22 Nov 2016
AbstractforMucoadhesive nanostructured lipid carriers (NLCs) as potential carriers for improving oral delivery of curcumin | Full Text | References | PDF (1.4 MB)
  • 413 Views
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Article
Comparative in vitro release and clinical pharmacokinetics of leuprolide from Luphere 3M Depot, a 3-month release formulation of leuprolide acetate
Sunghoon Park, Dong-Hwan Kim, Yoon Kim, Jeong Hwa Park, MinSeok Lee, Im-Sook Song & Chang-Koo Shim
Pages: 441-447
Published online: 22 Nov 2016
AbstractforComparative in vitro release and clinical pharmacokinetics of leuprolide from Luphere 3M Depot, a 3-month release formulation of leuprolide acetate | Full Text | References | PDF (1,000.3 KB)
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Article
Improvement of side-effects and treatment on the experimental colitis in mice of a resin microcapsule-loading hydrocortisone sodium succinate
Kai Dong, Hefeng Zhang, Yan Yan, Jinyao Sun, Yalin Dong, Ke Wang, Lu Zhang, Xianpeng Shi & Jianfeng Xing
Pages: 448-457
Published online: 21 Nov 2016
AbstractforImprovement of side-effects and treatment on the experimental colitis in mice of a resin microcapsule-loading hydrocortisone sodium succinate | Full Text | References | PDF (1.7 MB)
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Article
Preparation and physicochemical characterization of matrix pellets containing APIs with different solubility via extrusion process
Diána Hegyesi, Markus Thommes, Peter Kleinebudde, Tamás Sovány, Péter Kása Jr, András Kelemen, Klára Pintye-Hódi & Géza Regdon Jr
Pages: 458-464
Published online: 28 Nov 2016
AbstractforPreparation and physicochemical characterization of matrix pellets containing APIs with different solubility via extrusion process | Full Text | References | PDF (2.3 MB)
  • 191 Views
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Article
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones?
Francesca Sacchetti, Domenico D'Arca, Filippo Genovese, Salvatore Pacifico, Eleonora Maretti, Miriam Hanuskova, Valentina Iannuccelli, Maria Paola Costi & Eliana Leo
Pages: 465-473
Published online: 26 Dec 2016
AbstractforConveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? | Full Text | References | PDF (2.2 MB) | Supplemental
  • 125 Views
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Article
Efficacy, safety and mechanism of HP-β-CD-PEI polymers as absorption enhancers on the intestinal absorption of poorly absorbable drugs in rats
Hailong Zhang, Xiaoyan Huang, Yongjing Zhang & Yang Gao
Pages: 474-482
Published online: 05 Dec 2016
AbstractforEfficacy, safety and mechanism of HP-β-CD-PEI polymers as absorption enhancers on the intestinal absorption of poorly absorbable drugs in rats | Full Text | References | PDF (1.8 MB)
  • 164 Views
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Article
Improved stability of solid dispersions of manidipine with polyethylene glycol 4000/copovidone blends: application of ternary phase diagram
Benchawan Chamsai, Sontaya Limmatvapirat, Srisagul Sungthongjeen & Pornsak Sriamornsak
Pages: 483-491
Published online: 07 Dec 2016
AbstractforImproved stability of solid dispersions of manidipine with polyethylene glycol 4000/copovidone blends: application of ternary phase diagram | Full Text | References | PDF (1.8 MB)
  • 200 Views
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Article
Modification of gellan gum films by halloysite: physicochemical evaluation and drug permeation properties
Duangkamon Sakloetsakun & Thaned Pongjanyakul
Pages: 492-501
Published online: 14 Dec 2016
AbstractforModification of gellan gum films by halloysite: physicochemical evaluation and drug permeation properties | Full Text | References | PDF (1.5 MB)
  • 140 Views
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Article
SN-38 loading capacity of hydrophobic polymer blend nanoparticles: formulation, optimization and efficacy evaluation
Simona Dimchevska, Nikola Geskovski, Gjorgji Petruševski, Marina Chacorovska, Riste Popeski-Dimovski, Sonja Ugarkovic & Katerina Goracinova
Pages: 502-510
Published online: 20 Dec 2016
AbstractforSN-38 loading capacity of hydrophobic polymer blend nanoparticles: formulation, optimization and efficacy evaluation | Full Text | References | PDF (1.1 MB) | Supplemental
  • 355 Views
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Research Article

Article
Solid dispersions enhance solubility, dissolution, and permeability of thalidomide
Silvana A. Barea, Cristiane B. Mattos, Ariadne C. C. Cruz, Vitor C. Chaves, Rafael N. Pereira, Claudia M. O. Simões, Jadel M. Kratz & Letícia S. Koester
Pages: 511-518
Published online: 20 Dec 2016
AbstractforSolid dispersions enhance solubility, dissolution, and permeability of thalidomide | Full Text | References | PDF (1.8 MB) | Supplemental
  • 330 Views
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