Drug Development and Industrial Pharmacy, Volume 47, Issue 5 (2021)

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Drug Development and Industrial Pharmacy, Volume 47, Issue 5 (2021)

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Research Articles

Article
Physicochemical characterization of dapagliflozin and its solid-state behavior in stress stability test
Dong-Won Oh, Jinmann Chon, Ji-Hyun Kang, Chang-Soo Han, Dae Hwan Shin, Ju-Young Kim, Yun-Seok Rhee, Myung-Hee Chun, Dong-Wook Kim & Chun-Woong Park
Pages: 685-693
Published online: 03 May 2021
AbstractforPhysicochemical characterization of dapagliflozin and its solid-state behavior in stress stability test | Full Text | References | PDF (1.9 MB) | EPUB
  • 804 Views
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Article
Analytical approach for lubricant characterization of excipients using the surface replication method
Shinichi Saito, Takashi Osamura, Tadatsugu Tanino & Satomi Onoue
Pages: 694-698
Published online: 17 May 2021
AbstractforAnalytical approach for lubricant characterization of excipients using the surface replication method | Full Text | References | PDF (890 KB) | EPUB | Supplemental
  • 306 Views
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Article
Reckoning γ-Glutamyl-S-allylcysteine as a potential main protease (mpro) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation
Arun Parashar, Arpit Shukla, Ankush Sharma, Tapan Behl, Dweipayan Goswami & Vineet Mehta
Pages: 699-710
Published online: 07 Jun 2021
AbstractforReckoning γ-Glutamyl-S-allylcysteine as a potential main protease (mpro) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1767 Views
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Article
Effectual nanotherapy against oral squamous cell carcinoma
Rituraj Bharadwaj & Subhash Medhi
Pages: 711-724
Published online: 07 Jun 2021
AbstractforEffectual nanotherapy against oral squamous cell carcinoma | Full Text | References | PDF (3.7 MB) | EPUB
  • 324 Views
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Article
Characterization, in vitro dissolution, and pharmacokinetics of different batches of efavirenz raw materials
Danilo César Galindo Bedor, Noely Camila Tavares Cavalcanti Bedor, João Gomes Pontes Neto, Lucas José de Alencar Danda, Flávio Martins de Oliveira, Guilherme Henrique Onório de Oliveira, José Lamartine Soares Sobrinho, Eric Beyssac, Whocely Victor de Castro & Davi Pereira de Santana
Pages: 725-734
Published online: 09 Jun 2021
AbstractforCharacterization, in vitro dissolution, and pharmacokinetics of different batches of efavirenz raw materials | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 277 Views
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Article
Intranasal galantamine/chitosan complex nanoparticles elicit neuroprotection potentials in rat brains via antioxidant effect
Lamia Said Kandil, Ragwa M. Farid, Safaa S. ElGamal & Amira Sayed Hanafy
Pages: 735-740
Published online: 07 Jun 2021
AbstractforIntranasal galantamine/chitosan complex nanoparticles elicit neuroprotection potentials in rat brains via antioxidant effect | Full Text | References | PDF (839.5 KB) | EPUB
  • 310 Views
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Article
Establishment of quantitative methodology for sophoridine analysis and determination of its pharmacokinetics and bioavailability in rat
Mengchun Chen, Qi Jiang, Mingyao Zhang, Sailing Chen, Junsheng Lou, Yijie Chen, Fang Wang & Rongyue Wang
Pages: 741-747
Published online: 02 Jul 2021
AbstractforEstablishment of quantitative methodology for sophoridine analysis and determination of its pharmacokinetics and bioavailability in rat | Full Text | References | PDF (1,003.6 KB) | EPUB
  • 198 Views
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Article
Shellac- a natural carrier for colon targeting of indomethacin using hot melt extrusion
Dnyaneshwar N. Kapote & Karl G. Wagner
Pages: 748-757
Published online: 07 Jun 2021
AbstractforShellac- a natural carrier for colon targeting of indomethacin using hot melt extrusion | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 274 Views
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Article
Applicability of Raman and near-infrared spectroscopy in the monitoring of freeze-drying injectable ibuprofen
Maja Preskar, Klemen Korasa, Tomislav Vrbanec, Dejan Klement, Franc Vrečer & Mirjana Gašperlin
Pages: 758-769
Published online: 07 Jun 2021
AbstractforApplicability of Raman and near-infrared spectroscopy in the monitoring of freeze-drying injectable ibuprofen | Full Text | References | PDF (2.4 MB) | EPUB
  • 297 Views
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Article
Intra-articular formulation of colchicine loaded nanoemulsion systems for enhanced locoregional drug delivery: in vitro characterization, 99mTc coupling and in vivo biodistribution studies
Mohamed H. Aboumanei & Hend Fayez
Pages: 770-777
Published online: 07 Jun 2021
AbstractforIntra-articular formulation of colchicine loaded nanoemulsion systems for enhanced locoregional drug delivery: in vitro characterization, 99mTc coupling and in vivo biodistribution studies | Full Text | References | PDF (1.4 MB) | EPUB
  • 348 Views
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Article
Development, validation and application of physiologically based biopharmaceutics model to justify the change in dissolution specifications for DRL ABC extended release tablets
Swati Jaiswal, Tausif Ahmed, Sivacharan Kollipara, Mohit Bhargava & Siddharth Chachad
Pages: 778-789
Published online: 08 Jun 2021
AbstractforDevelopment, validation and application of physiologically based biopharmaceutics model to justify the change in dissolution specifications for DRL ABC extended release tablets | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 396 Views
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Article
Residence time and mixing capacity of a rotary tablet press feed frame
Maren Zimmermann & Markus Thommes
Pages: 790-798
Published online: 14 Jun 2021
AbstractforResidence time and mixing capacity of a rotary tablet press feed frame | Full Text | References | PDF (1.4 MB) | EPUB
  • 455 Views
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Article
Solid state characterization, solubility, intrinsic dissolution and stability behavior of allopurinol hydrochloride salt
Thúlio Wliandon Lemos Barbosa, Rafaela M. S. Talmeli, Homero de O. Junior, Antônio C. Doriguetto, Magali B. de Araújo & Rudy Bonfilio
Pages: 799-808
Published online: 09 Jun 2021
AbstractforSolid state characterization, solubility, intrinsic dissolution and stability behavior of allopurinol hydrochloride salt | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 250 Views
  • 1 CrossRef citations
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Article
Electrostatic deposition assisted preparation, characterization and evaluation of chrysin liposomes for breast cancer treatment
Prashant K. Deshmukh, Rakesh E. Mutha & Sanjay J. Surana
Pages: 809-819
Published online: 07 Jun 2021
AbstractforElectrostatic deposition assisted preparation, characterization and evaluation of chrysin liposomes for breast cancer treatment | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 247 Views
  • 3 CrossRef citations
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Article
Incentives to promote the US pharmaceutical innovation: empirical research based on the case of Epogen
Lin Zhang & Ji Wang
Pages: 820-824
Published online: 07 Jun 2021
AbstractforIncentives to promote the US pharmaceutical innovation: empirical research based on the case of Epogen | Full Text | References | PDF (561.6 KB) | EPUB
  • 321 Views
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Article
Development of purified cashew gum mucoadhesive buccal tablets containing nystatin for treatment of oral candidiasis
Ana Paula de Sá Pinto Abrahão Magalhães, Helena Keiko Toma, Flávia Almada do Carmo & Claudia Regina Elias Mansur
Pages: 825-837
Published online: 07 Jun 2021
AbstractforDevelopment of purified cashew gum mucoadhesive buccal tablets containing nystatin for treatment of oral candidiasis | Full Text | References | PDF (2.2 MB) | EPUB
  • 275 Views
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