Drug Metabolism Reviews, Volume 36, Issue 2 (2004)

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Drug Metabolism Reviews, Volume 36, Issue 2 (2004)

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Research Article

Article
Cytochrome P450: What Have We Learned and What Are the Future Issues?
F. Peter Guengerich
Pages: 159-197
Published online: 24 May 2004
First Page PreviewforCytochrome P450: What Have We Learned and What Are the Future Issues? | Full Text | References | PDF (310.1 KB)
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Article
Genotoxic Mechanism of Tamoxifen in Developing Endometrial Cancer
Sung Yeon Kim, Naomi Suzuki, Y. R. Santosh Laxmi & Shinya Shibutani
Pages: 199-218
Published online: 24 May 2004
AbstractforGenotoxic Mechanism of Tamoxifen in Developing Endometrial Cancer | Full Text | References | PDF (297.7 KB)
  • 259 Views
  • 39 CrossRef citations
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Article
“Allosterism” in the Elementary Steps of the Cytochrome P450 Reaction Cycle
Moon‐Young Yoon, A. Patricia Campbell & William M. Atkins
Pages: 219-230
Published online: 24 May 2004
Abstractfor“Allosterism” in the Elementary Steps of the Cytochrome P450 Reaction Cycle | Full Text | References | PDF (151.9 KB)
  • 155 Views
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Article
Modeling Kinetic Data from In Vitro Drug Metabolism Enzyme Experiments
Timothy S. Tracy Ph.D. & Matthew A. Hummel M.S.
Pages: 231-242
Published online: 24 May 2004
AbstractforModeling Kinetic Data from In Vitro Drug Metabolism Enzyme Experiments | Full Text | References | PDF (224.6 KB)
  • 645 Views
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Article
Polymorphic Cytochrome P450 2D6: Humanized Mouse Model and Endogenous Substrates
Ai‐Ming Yu, Jeffrey R. Idle & Frank J. Gonzalez
Pages: 243-277
Published online: 24 May 2004
AbstractforPolymorphic Cytochrome P450 2D6: Humanized Mouse Model and Endogenous Substrates | Full Text | References | PDF (516.9 KB)
  • 400 Views
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Article
Role of Human Aldehyde Dehydrogenases in Endobiotic and Xenobiotic Metabolism
Vasilis Vasiliou Ph.D., Aglaia Pappa & Tia Estey
Pages: 279-299
Published online: 24 May 2004
AbstractforRole of Human Aldehyde Dehydrogenases in Endobiotic and Xenobiotic Metabolism | Full Text | References | PDF (524.4 KB)
  • 1132 Views
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Article
Clinical Perspectives on Xenobiotic‐Induced Hepatotoxicity
Basuki Gunawan M.D. & Neil Kaplowitz M.D.
Pages: 301-312
Published online: 24 May 2004
AbstractforClinical Perspectives on Xenobiotic‐Induced Hepatotoxicity | Full Text | References | PDF (244.4 KB)
  • 361 Views
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Article
The Unique Regulation of Brain Cytochrome P450 2 (CYP2) Family Enzymes by Drugs and Genetics
Sharon Miksys Ph.D.B.Sc.M.Sc. & Rachel F. Tyndale
Pages: 313-333
Published online: 24 May 2004
AbstractforThe Unique Regulation of Brain Cytochrome P450 2 (CYP2) Family Enzymes by Drugs and Genetics | Full Text | References | PDF (638.5 KB)
  • 624 Views
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Article
Human Carbonyl Reduction Pathways and a Strategy for Their Study In Vitro
M. Jane Cox Rosemond & John S. Walsh
Pages: 335-361
Published online: 24 May 2004
AbstractforHuman Carbonyl Reduction Pathways and a Strategy for Their Study In Vitro | Full Text | References | PDF (236.4 KB)
  • 511 Views
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Article
Physiological Roles of Xanthine Oxidoreductase
Roger Harrison
Pages: 363-375
Published online: 24 May 2004
AbstractforPhysiological Roles of Xanthine Oxidoreductase | Full Text | References | PDF (212 KB)
  • 750 Views
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Article
Practical Aspects of Transporter Model Systems: A Case Study Involving SQV
Yaming Su, Sung‐hack Lee & Patrick J. Sinko R.Ph.Ph.D.
Pages: 377-389
Published online: 24 May 2004
AbstractforPractical Aspects of Transporter Model Systems: A Case Study Involving SQV | Full Text | References | PDF (174 KB)
  • 73 Views
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Article
Stress‐ (and Diet‐) Related Regulation of Hepatic Nuclear Receptors and Its Relevance for ABC‐Transporter Functions
Rinke Stienstra, Elgin Lichtenauer‐Kaligis Ph.D. & Michael Müller Ph.D.
Pages: 391-406
Published online: 24 May 2004
AbstractforStress‐ (and Diet‐) Related Regulation of Hepatic Nuclear Receptors and Its Relevance for ABC‐Transporter Functions | Full Text | References | PDF (190.7 KB)
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